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OALib Journal期刊
ISSN: 2333-9721
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主页: https://journals.plos.org/plosgenetics/

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Hypersensitivity of Primordial Germ Cells to Compromised Replication-Associated DNA Repair Involves ATM-p53-p21 Signaling

John C. Schimenti,Naoko Shima,Ruizhu Zeng,Suzanne A. Hartford,Teresa L. Southard,Yunhai Luo

R-loops Associated with Triplet Repeat Expansions Promote Gene Silencing in Friedreich Ataxia and Fragile X Syndrome

Matthias Groh,Michele M. P. Lufino,Natalia Gromak,Richard Wade-Martins

Copy Number Variation Is a Fundamental Aspect of the Placental Genome

Anton Valouev,David M. Gilbert,Edward B. Chuong,Juan Carlos Rivera-Mulia,Julie C. Baker,Roberta L. Hannibal

Activation of the Arabidopsis thaliana Immune System by Combinations of Common ACD6 Alleles

Detlef Weigel,Eunyoung Chae,Kirsten Bomblies,Lisa M. Smith,Marco Todesco,Maricris Zaidem,Roosa A. E. Laitinen,Sang-Tae Kim

The Nesprin Family Member ANC-1 Regulates Synapse Formation and Axon Termination by Functioning in a Pathway with RPM-1 and β-Catenin

Brock Grill,Erik D. Tulgren,Karla J. Opperman,Shane M. Turgeon

UVB Induces a Genome-Wide Acting Negative Regulatory Mechanism That Operates at the Level of Transcription Initiation in Human Cells

David Umlauf,Imre Boros,Làszlò Tora,Tao Ye,Zsuzsanna újfaludi,ákos Gyenis

Functional Diversification of Hsp40: Distinct J-Protein Functional Requirements for Two Prions Allow for Chaperone-Dependent Prion Selection

Julia M. Harris,Justin K. Hines,Milan J. Patel,Phil P. Nguyen,Zachary A. Sporn

Predicting the Minimal Translation Apparatus: Lessons from the Reductive Evolution of Mollicutes

Alain Blanchard,Aurélien Barré,Christine Citti,Dominique Fourmy,Florence Tardy,Fran？ois Thiaucourt,Henri Grosjean,Marc Breton,Pascal Sirand-Pugnet,Satoko Yoshizawa,Valérie de Crécy-Lagard

Determinative Developmental Cell Lineages Are Robust to Cell Deaths

Jian-Rong Yang,Jianzhi Zhang,Shuxiang Ruan

Meiotic Drive Impacts Expression and Evolution of X-Linked Genes in Stalk-Eyed Flies

Cara L. Brand,Gerald S. Wilkinson,Josephine A. Reinhardt,Kimberly A. Paczolt,Philip M. Johns,Richard H. Baker

Paternal Poly (ADP-ribose) Metabolism Modulates Retention of Inheritable Sperm Histones and Early Embryonic Gene Expression

Brian D. Gregory,Fan Li,Irina A. Zalenskaya,Mirella L. Meyer-Ficca,Motomasa Ihara,N. Adrian Leu,Ralph G. Meyer,Richard M. Schultz,Shilpa Rao

Genome-Wide Analysis of SREBP1 Activity around the Clock Reveals Its Combined Dependency on Nutrient and Circadian Signals

Aurélien Naldi,Béatrice Desvergne,Donatella Canella,Eugenia Migliavacca,Federica Gilardi,Gwendal Le Martelot,Micha？l Baruchet,Nicolas Guex,the CycliX Consortium

Noise Genetics: Inferring Protein Function by Correlating Phenotype with Protein Levels and Localization in Individual Human Cells

Alex Sigal,Anat Zimmer,Ariel Cohen,Eran Eden,Lydia Cohen,Naama Geva-Zatorsky,Ron Milo,Shlomit Farkash-Amar,Tamar Danon,Uri Alon

Crossover Patterning by the Beam-Film Model: Analysis and Implications

John Hutchinson,Liangran Zhang,Nancy Kleckner,Zhangyi Liang

Wnt Signaling Interacts with Bmp and Edn1 to Regulate Dorsal-Ventral Patterning and Growth of the Craniofacial Skeleton

Courtney Alexander,Pierre Le Pabic,Sarah Piloto,Thomas F. Schilling

Relationship Estimation from Whole-Genome Sequence Data

Chad D. Huff,David Witherspoon,Denise E. Mauldin,Gustavo Glusman,Hao Hu,Hong Li,Jared C. Roach,Juan Caballero,Leroy Hood,Lynn B. Jorde,Robert Hubley,Shankaracharya,Stephen L. Guthery

WNT7B Promotes Bone Formation in part through mTORC1

Congxin Lin,Emel Esen,Fanxin Long,Jeffrey M. Arbeit,Jianquan Chen,Kyu Sang Joeng,Liang Ma,Markus A. Rüegg,Michael N. Hall,Xiaolin Tu

Mlh2 Is an Accessory Factor for DNA Mismatch Repair in Saccharomyces cerevisiae

Anjana Srivatsan,Arshad Desai,Christopher D. Putnam,Christopher S. Campbell,Hans Hombauer,Kerstin Gries,Nikki Bowen,Richard D. Kolodner

A Chaperone-Assisted Degradation Pathway Targets Kinetochore Proteins to Ensure Genome Stability

Assen Roguev,Colin Gordon,Esben G. Poulsen,Franziska Kriegenburg,Nevan Krogan,Rasmus Hartmann-Petersen,Sofie Vincents Nielsen,Ursula Fleig,Visnja Jakopec

Extensive Diversity of Prion Strains Is Defined by Differential Chaperone Interactions and Distinct Amyloidogenic Regions

Heather L. True,Kevin C. Stein

Genetic Dissection of the Drosophila melanogaster Female Head Transcriptome Reveals Widespread Allelic Heterogeneity

Anthony D. Long,Brian J. Sanderson,Casey L. McNeil,Elizabeth G. King,Stuart J. Macdonald

An ARID Domain-Containing Protein within Nuclear Bodies Is Required for Sperm Cell Formation in Arabidopsis thaliana

Binglian Zheng,Hui He,Sheila McCormick,Wenye Wu,Yanhua Zheng

Arabidopsis thaliana WAPL Is Essential for the Prophase Removal of Cohesin during Meiosis

Christopher A. Makaroff,Kuntal De,Laura Krueger,Lauren Sterle,Xiaohui Yang

A Novel MMP12 Locus Is Associated with Large Artery Atherosclerotic Stroke Using a Genome-Wide Age-at-Onset Informed Approach

Agnieszka Slowik,Ale Algra,Arne Lindgren,Braxton D. Mitchell,Cathie Sudlow,Cathryn M. Lewis,Christopher Levi,Danish Saleheen,Elizabeth G. Holliday,Emma Raitoharju,Giorgio B. Boncoraglio,Hugh S. Markus,James F. Meschia,Jane M. Maguire,John R. Attia,Jonathan Rosand,Joshua C. Bis,Kari-Matti M？kel？,Kerri L. Wiggins,Laura L. Kilarski,METASTROKE, International Stroke Genetics Consortium, Wellcome Trust Case Consortium 2 (WTCCC2),Martin Dichgans,Matthew Traylor,Matthew Walters,Mike A. Nalls,Niku Oksala,Pankaj Sharma,Paul I. W. de Bakker,Peter M. Rothwell,Rainer Malik,Robin Lemmens,Sefanja Achterberg,Steve Bevan,Steven J. Kittner,Terho Lehtim？ki,Vincent Thijs,Wei Zhao,William J. Devan,Yu-Ching Cheng

G×G×E for Lifespan in Drosophila: Mitochondrial, Nuclear, and Dietary Interactions that Modify Longevity

Chen-Tseh Zhu,David M. Rand,Paul Ingelmo

MDRL lncRNA Regulates the Processing of miR-484 Primary Transcript by Targeting miR-361

Bo Long,Cui-Yun Liu,Fang Liu,Jian-Xun Wang,Kun Wang,Lu-Yu Zhou,Na Li,Pei-Feng Li,Teng Sun,Yin Wang

Intrapopulation Genome Size Variation in D. melanogaster Reflects Life History Variation and Plasticity

Aaron M. Tarone,Andrew M. Quinn,Astha Ahuja,Ben Alfrejd,Carl E. Hjelmen,Francisco E. Gomez,J. Spencer Johnston,Kristi L. Moore,Lisa L. Ellis,Trudy F. C. Mackay,Wen Huang

The ABI4-Induced Arabidopsis ANAC060 Transcription Factor Attenuates ABA Signaling and Renders Seedlings Sugar Insensitive when Present in the Nucleus

Bo Yu,Hua Zhou,Ping Li,Rhonda C. Meyer,Sheng Teng,Sjef C. Smeekens,Suli Chen,Xiaoliang Shi,Yan Zhou,Yu Peng,Yufeng Wang

CYP6 P450 Enzymes and ACE-1 Duplication Produce Extreme and Multiple Insecticide Resistance in the Malaria Mosquito Anopheles gambiae

Adam M. Jenkins,Benjamin G. Koudou,Christopher M. Jones,Constant V. Edi,David Weetman,Guillaume K. Kétoh,Hilary Ranson,John Essandoh,Kimberly Regna,Luc Djogbénou,Marc A. T. Muskavitch,Mark J. I. Paine,Martin J. Donnelly,Rodolphe Poupardin

Intron Retention in the 5′UTR of the Novel ZIF2 Transporter Enhances Translation to Promote Zinc Tolerance in Arabidopsis

Alekos Athanasiadis,Estelle Remy,Isabel Sá-Correia,Miguel C. Teixeira,Mohamed A. M. Hussein,Paula Duque,Rita A. Batista,Tania R. Cabrito

Sugar and Chromosome Stability: Clastogenic Effects of Sugars in Vitamin B6-Deficient Cells

Antonio Marzio,Chiara Merigliano,Fiammetta Vernì,Maurizio Gatti

Sex Chromosome Turnover Contributes to Genomic Divergence between Incipient Stickleback Species

Asao Fujiyama,Atsushi Toyoda,Catherine L. Peichel,Jun Kitano,Katsushi Yamaguchi,Kohta Yoshida,Manabu Kume,Masakado Kawata,Mitsuyasu Hasebe,Seiichi Mori,Shuji Shigenobu,Takashi Makino

DUF1220 Dosage Is Linearly Associated with Increasing Severity of the Three Primary Symptoms of Autism

James M. Sikela,Jonathan M. Davis,Jonathon Keeney,Laura Dumas,Nathan Anderson,Veronica B. Searles

Evidence for Divisome Localization Mechanisms Independent of the Min System and SlmA in Escherichia coli

Boyd T. Warren,David J. Sherratt,Jaan M？nnik,Matthew W. Bailey,Paola Bisicchia

Demography and the Age of Rare Variants

Gil McVean,Iain Mathieson

A Mutation in the FAM83G Gene in Dogs with Hereditary Footpad Hyperkeratosis (HFH)

Anne Thomas,Caroline Dufaure de Citres,Claude Schelling,Cord Dr？gemüller,Cécile Kaerle,Doreen Becker,Eliane J. Müller,Jocelyn Plassais,Michaela Dr？gemüller,Monika M. Welle,Petra Roosje,Tosso Leeb,Vidhya Jagannathan

Playing RNase P Evolution: Swapping the RNA Catalyst for a Protein Reveals Functional Uniformity of Highly Divergent Enzyme Forms

Andreas Hartig,Christoph Weber,Roland K. Hartmann,Walter Rossmanith

Rgs6 is Required for Adult Maintenance of Dopaminergic Neurons in the Ventral Substantia Nigra

Jacques Drouin,Jianqi Yang,Panojot Bifsha,Rory A. Fisher

Recurrent Loss of Specific Introns during Angiosperm Evolution

Hao Wang,Jeffrey L. Bennetzen,Katrien M. Devos

Increased and Imbalanced dNTP Pools Symmetrically Promote Both Leading and Lagging Strand Replication Infidelity

Andrei Chabes,Anna Karin Nilsson,Balasubramanyam Chittoor,Danielle L. Watt,Robert J. Buckland,Thomas A. Kunkel

Insights into the Dekkera bruxellensis Genomic Landscape: Comparative Genomics Reveals Variations in Ploidy and Nutrient Utilisation Potential amongst Wine Isolates

Anthony R. Borneman,Chris D. Curtin,Paul J. Chambers,Ryan Zeppel

Oxidative Stress Is Not a Major Contributor to Somatic Mitochondrial DNA Mutations

Edward J. Fox,Fernando Cardozo-Pelaez,Joshua J. Hewitt,Leo J. Pallanck,Leslie S. Itsara,Monica Sanchez-Contreras,Scott R. Kennedy,Selina Yu

Microbial Succession in the Gut: Directional Trends of Taxonomic and Functional Change in a Birth Cohort of Spanish Infants

Alberto Pascual-García,Alejandro Artacho,Juan José Abellán,M. Pilar Francino,Maria Loreto Ferrús,María José Gosalbes,Yvonne Vallès

Discovery and Functional Annotation of SIX6 Variants in Primary Open-Angle Glaucoma

Allison Ashley-Koch,Benjamin T. Whigham,Chunyan Qiao,Edwin C. Oh,Janey L. Wiggs,Louis R. Pasquale,Megan Ulmer Carnes,Melanie E. Garrett,Michael A. Hauser,NEIGHBORHOOD Consortium Investigators,Nicholas Katsanis,R. Rand Allingham,Shane Havens,Yangfan P. Liu

The Groucho Co-repressor Is Primarily Recruited to Local Target Sites in Active Chromatin to Attenuate Transcription

Aamna Kaul,Barbara H. Jennings,Eugene Schuster

Glycogen Synthase Kinase (GSK) 3β Phosphorylates and Protects Nuclear Myosin 1c from Proteasome-Mediated Degradation to Activate rDNA Transcription in Early G1 Cells

Aishe A. Sarshad,Anne Von Euler,Bader Al-Muzzaini,Douglas Lamont,Laura Borgonovo-Brandter,Martin Corcoran,Neus Visa,Piergiorgio Percipalle

A Conserved Dopamine-Cholecystokinin Signaling Pathway Shapes Context–Dependent Caenorhabditis elegans Behavior

Belinda Barbagallo,Christopher M. Clark,Christopher M. Lambert,Denis Touroutine,Jason Climer,Mark J. Alkema,Michael M. Francis,Raja Bhattacharya

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