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OALib Journal期刊
ISSN: 2333-9721
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主页: https://journals.plos.org/plosgenetics/

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Break-Induced Replication Requires DNA Damage-Induced Phosphorylation of Pif1 and Leads to Telomere Lengthening

Lea A. Harrington,Svetlana Makovets,Yulia Vasianovich

Caudal Regulates the Spatiotemporal Dynamics of Pair-Rule Waves in Tribolium

Ezzat El-Sherif,Jinping Fu,Susan J. Brown,Xin Zhu

HAM-5 Functions As a MAP Kinase Scaffold during Cell Fusion in Neurospora crassa

Abigail C. Leeder,Charles Ansong,David G. Camp II,Feng Yang,N. Louise Glass,Richard D. Smith,Trevor L. Starr,Wilfried Jonkers,Yuexi Wang

Quantitative Genetics of CTCF Binding Reveal Local Sequence Effects and Different Modes of X-Chromosome Association

Anna Battenhouse,Bum-Kyu Lee,Ewan Birney,Fengtang Yang,Gregory E. Crawford,Ian Dunham,Jason D. Lieb,Richard Durbin,Sander W. Timmer,Sandra Louzada,Vishwanath R. Iyer,Yunyun Ni,Zhihao Ding

Out of Balance: R-loops in Human Disease

Matthias Groh,Natalia Gromak

Let's Face It—Complex Traits Are Just Not That Simple

Benedikt Hallgrimsson,Ralph S. Marcucio,Richard Spritz,Washington Mio

Scribble Modulates the MAPK/Fra1 Pathway to Disrupt Luminal and Ductal Integrity and Suppress Tumour Formation in the Mammary Gland

Helen B. Pearson,Jane E. Visvader,Julie M. Sheridan,Kara L. Britt,Laura L. Yates,Lorey K. Smith,Nathan J. Godde,Patrick O. Humbert,Ryan C. Galea

Activating Transcription Factor 6 Is Necessary and Sufficient for Alcoholic Fatty Liver Disease in Zebrafish

Ana M. Vacaru,Christoph Buettner,Claudia Lindtner,Deanna L. Howarth,Kirsten C. Sadler,Orkhontuya Tsedensodnom,Ravi Sachidanandam,Taisa Vasilkova

A Genome-Wide Assessment of the Role of Untagged Copy Number Variants in Type 1 Diabetes

Chris Wallace,Corina Shtir,Daniel Gallo,Deborah Smyth,John A. Todd,Manuela Zanda,Matthew E. Hurles,Neil Walker,Stephen S. Rich,Suna Onengut-Gumuscu,Vincent Plagnol

Basement Membrane and Cell Integrity of Self-Tissues in Maintaining Drosophila Immunological Tolerance

Kwang-Min Choe,Moon Jong Kim

A Mouse Model Uncovers LKB1 as an UVB-Induced DNA Damage Sensor Mediating CDKN1A (p21WAF1/CIP1) Degradation

Ana Vivancos,Berta Ferrer,Boris Bastian,Elena González-Sánchez,Francesc Canals,Javier Cortés,Javier Hernández-Losa,Joan Josep Bech-Serra,Juan Martín-Caballero,Juan ángel Recio,Juana Maria Flores,Judit Grueso,Rosa Gil,Rosaura Esteve-Puig,Santiago Ramón y Cajal,Teresa Moliné,Vicen？ García-Patos

An AGEF-1/Arf GTPase/AP-1 Ensemble Antagonizes LET-23 EGFR Basolateral Localization and Signaling during C. elegans Vulva Induction

Christian E. Rocheleau,Juan M. Escobar-Restrepo,Olga Skorobogata

BMPs Regulate msx Gene Expression in the Dorsal Neuroectoderm of Drosophila and Vertebrates by Distinct Mechanisms

Alexander Springhorn,Erika Kague,Erika Taylor,Ethan Bier,Francisco F. Esteves,George Pyrowolakis,Shannon Fisher

Hsp40s Specify Functions of Hsp104 and Hsp90 Protein Chaperone Machines

Brittany-Lee Roberts,Daniel C. Masison,Ivan Albino-Flores,Michael Reidy,Ruchika Sharma,Shankar Shastry,Sue Wickner

Oligoasthenoteratozoospermia and Infertility in Mice Deficient for miR-34b/c and miR-449 Loci

Chiara Azzi,Christian Much,Dónal O'Carroll,Emerald Perlas,Kasper Dindler Rasmussen,Marcos Morgan,Monica Di Giacomo,Stefano Comazzetto

Tissue-Specific RNA Expression Marks Distant-Acting Developmental Enhancers

Alex S. Nord,Axel Visel,Edward M. Rubin,Han Wu,Jennifer A. Akiyama,Len A. Pennacchio,Malak Shoukry,Veena Afzal

Hydroxymethylated Cytosines Are Associated with Elevated C to G Transversion Rates

Ben Lehner,Fran Supek,Petra Hajkova,Tobias Warnecke

Arabidopsis RRP6L1 and RRP6L2 Function in FLOWERING LOCUS C Silencing via Regulation of Antisense RNA Synthesis

Julia A. Chekanova,Jun-Hye Shin

A HECT Ubiquitin-Protein Ligase as a Novel Candidate Gene for Altered Quinine and Quinidine Responses in Plasmodium falciparum

Astutiati Nurhasanah,Cecilia P. Sanchez,Chia-Hao Liu,Jianbing Mu,Marek Cyrklaff,Michael Lanzer,Michael T. Ferdig,Sybille Mayer,Wilfred D. Stein

Fine Tuning of the UPR by the Ubiquitin Ligases Siah1/2

David Bowtell,Eric Lau,Gabriel Haddad,Hang Yao,Hyungsoo Kim,Jaeseok Han,Jian-Liang Li,Laurence M. Brill,Marzia Scortegagna,Randal J. Kaufman,Ze'ev A. Ronai

Salt-Induced Stabilization of EIN3/EIL1 Confers Salinity Tolerance by Deterring ROS Accumulation in Arabidopsis

Hongwei Guo,Huaiqiu Zhu,Hui Shi,Jinying Peng,Longshu Yang,Wenyang Li,Xing Wen,Zhonghai Li

Genes That Bias Mendelian Segregation

Fabienne Malagnac,Hervé Lalucque,Philippe Silar,Pierre Grognet

Netrins and Wnts Function Redundantly to Regulate Antero-Posterior and Dorso-Ventral Guidance in C. elegans

Joseph G. Culotti,Naomi Levy-Strumpf

Deep Evolutionary Comparison of Gene Expression Identifies Parallel Recruitment of Trans-Factors in Two Independent Origins of C4 Photosynthesis

Britta M. C. Kümpers,Julian M. Hibberd,Richard D. Smith-Unna,Steven Kelly,Sylvain Aubry

Rosa26-GFP Direct Repeat (RaDR-GFP) Mice Reveal Tissue- and Age-Dependence of Homologous Recombination in Mammals In Vivo

Bevin P. Engelward,Danielle N. Chow,Dushan N. Wadduwage,Elizabeth A. Rowland,Jagath Rajapakse,Jennifer E. Kay,Kelly E. Winther,Lara S. Collier,Li Na,Michelle R. Sukup-Jackson,Orsolya Kiraly,Peter T. C. So,Takafumi Kimoto,Tetsuya Matsuguchi,Vidya S. Jonnalagadda,Vijay R. Singh,Vilena I. Maklakova

Ribosome Rescue and Translation Termination at Non-Standard Stop Codons by ICT1 in Mammalian Mitochondria

Knud H. Nierhaus,Nono Takeuchi,Shiori Akabane,Takuya Ueda

Translational Regulation of the DOUBLETIME/CKIδ/ε Kinase by LARK Contributes to Circadian Period Modulation

F. Rob Jackson,Gerard P. McNeil,Yanmei Huang

Muscular Dystrophy-Associated SUN1 and SUN2 Variants Disrupt Nuclear-Cytoskeletal Connections and Myonuclear Organization

Elisabetta Mattioli,Farhana Haque,Giovanna Lattanzi,Gregg G. Gundersen,Howard J. Worman,Kees R. Straatman,Manfred Wehnert,Marta Columbaro,Peter Meinke,Sue Shackleton,Susumu Antoku

A Complex Genetic Switch Involving Overlapping Divergent Promoters and DNA Looping Regulates Expression of Conjugation Genes of a Gram-positive Plasmid

Carlos Alfonso,Fernando Rojo,Gayetri Ramachandran,Juan Roman Luque-Ortega,Ling J. Wu,Luis Yuste,Praveen K. Singh,Wilfried J. J. Meijer

Juvenile Hormone-Receptor Complex Acts on Mcm4 and Mcm7 to Promote Polyploidy and Vitellogenesis in the Migratory Locust

Feng Jiang,Jiasheng Song,Shun Deng,Shutang Zhou,Virginia K. Walker,Wei Guo,Zhiming Wang,Zhongxia Wu

Systematic Dissection of Coding Exons at Single Nucleotide Resolution Supports an Additional Role in Cell-Specific Transcriptional Regulation

Angel A. Ku,Beth Martin,Gregory M. Findlay,Jay Shendure,Jingjing Zhao,Mee J. Kim,Nadav Ahituv,Ramon Y. Birnbaum,Robert J. A. Bell,Robin P. Smith,Rupali P. Patwardhan

Co-regulated Transcripts Associated to Cooperating eSNPs Define Bi-fan Motifs in Human Gene Networks

Anat Kreimer,Itsik Pe'er

Regulation of Arabidopsis Flowering by the Histone Mark Readers MRG1/2 via Interaction with CONSTANS to Modulate FT Expression

Ai-Wu Dong,Wen Jiang,Yanchao Liu,Ying Huang,Yu Yu,Zepeng Li,Zhongyuan Bu

Rejuvenation of Meiotic Cohesion in Oocytes during Prophase I Is Required for Chiasma Maintenance and Accurate Chromosome Segregation

Charlotte A. Jeffreys,Katherine A. Weng,Sharon E. Bickel

Positive Selection and Multiple Losses of the LINE-1-Derived L1TD1 Gene in Mammals Suggest a Dual Role in Genome Defense and Pluripotency

Harmit S. Malik,Holly A. Wichman,Janet M. Young,Lei Yang,Rafik Neme,Richard N. McLaughlin Jr.

Nephronophthisis-Associated CEP164 Regulates Cell Cycle Progression, Apoptosis and Epithelial-to-Mesenchymal Transition

Amiya K. Ghosh,Friedhelm Hildebrandt,Gisela G. Slaats,Glenn van de Hoek,Iain A. Drummond,Indra A. Shaltiel,Ive Logister,Lucas L. Falke,Marianne C. Verhaar,Marijn F. Stokman,Rachel H. Giles,Roel Goldschmeding,Stéphanie Le Corre,Timothy D. Klasson,Tri Q. Nguyen

Targeted H3R26 Deimination Specifically Facilitates Estrogen Receptor Binding by Modifying Nucleosome Structure

Gordon L. Hager,John T. Lis,Lynne Anguish,Lyuba Varticovski,Michael J. Guertin,Scott A. Coonrod,Sohyoung Kim,Xuesen Zhang

The Kinesin AtPSS1 Promotes Synapsis and is Required for Proper Crossover Distribution in Meiosis

Afef Lemhemdi,Aurélie Hurel,Christine Horlow,Cécile Larchevêque,Laurence Cromer,Liudmila Chelysheva,Maria Cuacos,Raphael Mercier,Susan J. Armstrong,Yann Duroc

Genetic Modifiers of Neurofibromatosis Type 1-Associated Café-au-Lait Macule Count Identified Using Multi-platform Analysis

Alexander F. Wilson,Alexander Pemov,Andrea M. Baldwin,Brigitte C. Widemann,Douglas R. Stewart,Heejong Sung,Hyo Jung Lee,James C. Mullikin,Jennifer L. Sloan,Joseph F. Boland,Kristine M. Jones,NISC Comparative Sequencing Program,Paula L. Hyland,Sara E. Bass,Sarah L. Ruppert,Xijun Zhang

The Proper Splicing of RNAi Factors Is Critical for Pericentric Heterochromatin Assembly in Fission Yeast

Haitong Hou,James J. Moresco,John R. Yates III,Patricia G. Tu,Peter L. Nagy,Scott P. Kallgren,Songtao Jia,Stuart Andrews,Xavier Tadeo

Distinct Genealogies for Plasmids and Chromosome

Mark Achtman,Zhemin Zhou

Echoes of the Past: Hereditarianism and A Troublesome Inheritance

Marcus Feldman

Keep on Laying Eggs Mama, RNAi My Reproductive Aging Blues Away

Kerry Kornfeld,Sandeep Kumar,Zuzana Kocsisova

Recovery from an Acute Infection in C. elegans Requires the GATA Transcription Factor ELT-2

Alejandro Aballay,Brian Head

Tetraspanin (TSP-17) Protects Dopaminergic Neurons against 6-OHDA-Induced Neurodegeneration in C. elegans

Alexander Holmes,Anton Gartner,Neda Masoudi,Pablo Ibanez-Cruceyra,Sarah-Lena Offenburger

PRL1, an RNA-Binding Protein, Positively Regulates the Accumulation of miRNAs and siRNAs in Arabidopsis

Bin Yu,Shuxin Zhang,Yuhui Liu

Defining NELF-E RNA Binding in HIV-1 and Promoter-Proximal Pause Regions

Abdullah Ozer,Brian S. White,Colin T. Waters,David Shalloway,Harold G. Craighead,Hojoong Kwak,John M. Pagano,John T. Lis,Kylan Szeto,Rebekka O. Sprouse

Genetic Determinants of Long-Term Changes in Blood Lipid Concentrations: 10-Year Follow-Up of the GLACIER Study

Dmitry Shungin,Emily Sonestedt,Frida Renstr？m,G？ran Hallmans,Inês Barroso,Marju Orho-Melander,Olle Melander,Paul W. Franks,Peter Nilsson,Robert W. Koivula,Stefan A. Escher,Tibor V. Varga

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