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International Journal of Biological Sciences

ISSN Print: 1449-2288

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主页: http://www.ijbs.com

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Astemizole Inhibits mTOR Signaling and Angiogenesis by Blocking Cholesterol Trafficking

Baoyuan Zhang,Changjie Wu,Eun Ju Yang,Harapriya Chakravarty,Ho Jeong Kwon,Joong Sup Shim,Jun O. Liu,Junfang Lyu,Kin Yip Tam,Nana Ai,Ruo-Jing Li,Sarah A. Head,Shaolin Zhang,Wei Ge,Yifan Liu,Yongjun Dang

miR-487b-3p Suppresses the Proliferation and Differentiation of Myoblasts by Targeting IRS1 in Skeletal Muscle Myogenesis

Chunlei Zhang,Hong Chen,Jian Wang,Jiaoyan Tan,Lingzhi Yang,Linyong Hu,Qi Qi,Xingtang Fang,Yanhong Wang

Eaf1 and Eaf2 mediate zebrafish dorsal-ventral axis patterning via suppressing Wnt/β-Catenin activity

Gang Ouyang,Jing-Xia Liu,Qin-Han Xu,Ting Zhang,XueDong Yu,XunWei Xie

Dentinal mineralization is not limited in the mineralization front but occurs along with the entire odontoblast process

C. Li,H. Zhao,J.Q. Feng,K. Wang,X. Liu,X. Wang,Y. Jing,Y. Ren,Z. Wang

Phosphorylation of SMC1A promotes hepatocellular carcinoma cell proliferation and migration

Fei Yi,Liang Wang,Liu Cao,Naijin Zhang,Shi Wei,Xiaoyu Song,Ying Zhang,Zhijun Wang,Zhuo Wang,Ziwei Li

Overexpression of Toll-like Receptor 4-linked Mitogen-activated Protein Kinase Signaling Contributes to Internalization of Escherichia coli in Sheep

Guoshi Liu,Jiahao Wang,Jinlong Zhang,Shoulong Deng,Sutian Wang,Xiaojing Jiang,Xiaosheng Zhang,Yang Cao,Zhengxing Lian

Zika Virus Envelope Protein induces G2/M Cell Cycle Arrest and Apoptosis via an Intrinsic Cell Death Signaling Pathway in Neuroendocrine PC12 Cells

Andrew Li,Hongwei Li,Huangyao Chen,Huiying Chen,Jingjing Li,Jinlong Li,Jun Liu,Mingyu Xu,Qingqing Li,Wangsheng Wu,Weiwang Gu,Wenhan Liang,Xiangsheng Cai,Xiaoxin Li,Xinglu Chen,Xinyue Duan,Yingying Mao,Zhenzhen Qiu

Non-coding RNA-linked epigenetic regulation in cardiac hypertrophy

Jing Liu,Kun Wang,Murugavel Ponnusamy,Peifeng Li,Qi Wang,Sheng Xu,Yanfang Zhao,Yanhan Dong,Yanhui Zhang

KDM5B demethylates H3K4 to recruit XRCC1 and promote chemoresistance

Bingluo Zhou,Dingwei Chen,Hongchuan Jin,Jianwei Zhou,Jinye Xu,Lifeng Feng,Liyuan Zhu,Mengjiao Han,Qi Wei,Shouyu Wang,Wenxia Xu,Xian Wang,Xiaoya Zhao,Zhinong Jiang

Exosomal Metastasis？Associated Lung Adenocarcinoma Transcript 1 Promotes Angiogenesis and Predicts Poor Prognosis in Epithelial Ovarian Cancer

Jun-Jun Qiu,Ke-Qin Hua,Ting-Ting Zheng,Xiao-Jing Lin,Xiao-Yan Tang,Ying-Ying Lin

Comparison of Prognostic Indices in NSCLC Patients with Brain Metastases after Radiosurgery

Hong Xiang Gao,Jian Fei Du,Jian Mao,Nan Jiang,Qi Zhao,Shi Gao Huang,Wen Xing Kang,Xue Cheng Zhang

The roles of Wnt/β-catenin signaling pathway related lncRNAs in cancer

Hao-Yu Quan,Jin Bai,Jin-Jin Liu,Jun-Nian Zheng,Min-Le Li,Ping-Fu Hou,Teng-Teng Li,Tian Lin,Xiao-Yi Hu

A chemosensory protein MsepCSP5 involved in chemoreception of oriental armyworm Mythimna separata

Aneela Younas,Hazem Abdelnabby,Man-Qun Wang,Muhammad Irfan Waris,Muhammad Shaaban,Muhammad Tahir ul Qamar,Xiang-Qian Chang

Hepatoprotective effects of limb ischemic post-conditioning in hepatic ischemic rat model and liver cancer patients via PI3K/ERK pathways

Dan Qi,Erxi Wu,Fengfei Wang,Jason H. Huang,Sen Sheng,Shuang Zhou,Xiongwei Huo,Yanfeng Gao,Yi Lv,Yue Zhou

Exosomes Derived from Hypoxic Colorectal Cancer Cells Transfer Wnt4 to Normoxic Cells to Elicit a Prometastatic Phenotype

Fan Yang,Mingli Yang,Yong Feng,Yunze Li,Zhe Huang

MiR-21-mediated Metabolic Alteration of Cancer-associated Fibroblasts and Its Effect on Pancreatic Cancer Cell Behavior

Jiancang Ma,Shuo Chen,Tao Shan,Wanrun Lin,Wei Li,Xi Chen,Ya'an Kang

Aryl Hydrocarbon Receptor Activation Modulates Intestinal Epithelial Barrier Function by Maintaining Tight Junction Integrity

Guoqing Chen,Hua Yang,Kun Yu,Liangzi Li,Min Yu,Pengyuan Xu,Qimeng Wang,Weidong Xiao,Xiangsheng Li,Yuanhang Ma,Zhicao Zhang

Angiotensin 1-7 Overexpression Mediated by a Capsid-optimized AAV8 Vector Leads to Significant Growth Inhibition of Hepatocellular Carcinoma In vivo

Andrew Li,Baihong Chen,Colin Sumners,Hongwei Li,Hongyan Du,Huiying Chen,Jinlong Li,Na Bai,Nana Pei,Renhe Yan,Shengqi Wang,Xinglu Chen,Xuejun Wang,Yanling Zhang,Yingying Mao

Trichosanthin enhances sensitivity of non-small cell lung cancer (NSCLC) TRAIL-resistance cells

Chengcheng You,Chunyang Li,Conghua Xie,Feng Wang,Guiliang Tang,Junhong Zhang,Nannan Zhang,Shijing Ma,Shiyu Zhang,Wenjie Sun,Xiaoli Tian,Xuefeng Liu,Yan Gong,Yingming Sun,Yu Xiao,Yuan Luo

Fam60al as a novel factor involved in reprogramming of somatic cell nuclear transfer in zebrafish (Danio rerio)

Binbin Tao,Hongling Hu,Ji Chen,Wei Hu,Zuoyan Zhu

Vital Roles of β-catenin in Trans-differentiation of Chondrocytes to Bone Cells

Jian Q. Feng,Junjun Jing,Ke Wang,Kevin Chan,Robert J. Hinton,Stephen E. Harris,Yan Jing

Glaucocalyxin A induces G2/M cell cycle arrest and apoptosis through the PI3K/Akt pathway in human bladder cancer cells

Abai Xu,Chaoming Li,Chunxiao Liu,Hulin Li,Jinlin Xie,Linglong Huang,Masami Watanabe,Naijin Xu,Peng Huang,Wenfeng Lin,Yubo Gao

Bmi1 Deficient Mice Exhibit Male Infertility

Dengshun Miao,Qian Zhang,Rong Wang,Weiwei Sun,Xiuliang Dai,Zhenzhen Yu

Molecular Networks of Postia placenta Involved in Degradation of Lignocellulosic Biomass Revealed from Metadata Analysis of Open Access Gene Expression Data

Ayyappa Kumar Sista Kameshwar,Wensheng Qin

Environmental adaptation of Acanthamoeba castellanii and Entamoeba histolytica at genome level as seen by comparative genomic analysis

Hanna Kmita,Tabea Kischka,Victoria Shabardina,Wojciech Maka？owski,Yutaka Suzuki

Elongator promotes the migration and invasion of hepatocellular carcinoma cell by the phosphorylation of AKT

Huijun Yu,Jian Shen,Jingchun Guo,Wei Zhou,Wenxiang Wei,Xiaxia Zhu,Yi Xu,Yuan Ji,Zhi Pang

The Suppression of Medium Acidosis Improves the Maintenance and Differentiation of Human Pluripotent Stem Cells at High Density in Defined Cell Culture Medium

Chengcheng Song,Edwin Chong Wing Cheung,Guokai Chen,Kai Lu,Weiwei Liu,Zhili Ren,Zhou Zhou

Role of Plant Derived Alkaloids and Their Mechanism in Neurodegenerative Disorders

Aroona Razzaq,Azhar Rasul,Ghulam Hussain,Haseeb Anwar,Jiang Li,Muhammad Ali,Nimra Aziz,Wei Wei,Xiaomeng Li

Effect of IL-18 on the Expansion and Phenotype of Human Natural Killer Cells: Application to Cancer Immunotherapy

Asuka Kumagai,Haruki Okamura,Hiroaki Senju,Hiroshi Mukae,Hiroyuki Yamaguchi,Katsumi Nakatomi,Kengo Shiraishi,Mitsuhiro Nakamura,Shota Fukami,Yoichi Nakamura,Yoshimasa Tanaka,Yuka Harada

Recalling Cohnheim's Theory: Papillary Renal Cell Tumor as a Model of Tumorigenesis from Impaired Embryonal Differentiation to Malignant Tumors in Adults

Anetta Nagy,Daniel Banyai,Donat P. Sarlos,Gyula Kovacs

Frizzled7 Promotes Epithelial-to-mesenchymal Transition and Stemness Via Activating Canonical Wnt/β-catenin Pathway in Gastric Cancer

Changhua Zhang,Dong Wang,Guanman Li,Haibo Liu,Jiong Bi,Li Fu,Qiao Su,Wen Li,Wenhui Zhang,Xiaohui Huang,Yu Chen,Yulong He,Zhenhai Lu

A dual-specific IGF-I/II human engineered antibody domain inhibits IGF signaling in breast cancer cells

Chuxia Deng,Dafeng Chu,Dimiter S. Dimitrov,Guixing Ma,Hongmin Zhang,Jie Liu,Pu Wang,Qi Zhao,Qiang Chen,Weizao Chen,Xiaohua Douglas Zhang,Yaming Shan,Zhizhen Chen

Berberine suppresses apoptosis and extracellular matrix (ECM) degradation in nucleus pulposus cells and ameliorates disc degeneration in a rodent model

Chenggui Wang,Chengxuan Tang,Jian Chen,Jian Xiao,Jianle Wang,Qian Tang,Sinan Khor,Xiangyang Wang,Xibang Chen,Yiting Lou,Yu Chen,Zengjie Zhang,Zengming Zheng,Zhouguang Wang

Incorporation of DDR2 clusters into collagen matrix via integrin-dependent posterior remnant tethering

Baomei Wang,Hao Cai,Jin'e Liu,Jun Liu,Tingting Li,Yunfeng Feng

FGF23 and Fetuin-A Interaction in the Liver and in the Circulation

Aldamaria Puliti,Carlo M Alfieri,Deborah Mattinzoli,Elena Trombetta,Koji Tsugawa,Lorenza Lazzari,Luca Valenti,Masami Ikehata,Paola Dongiovanni,Piergiorgio Messa

Instillation of particulate matter 2.5 induced acute lung injury and attenuated the injury recovery in ACE2 knockout mice

Cheng-Yi Chen,Chih-Sheng Lin,Chin-Hung Tsai,Chung-I Lin,Wen-Yeh Hsieh,Yi-Chang Lin,Yu-Ling Sun

Identification of key genes and pathways in human clear cell renal cell carcinoma (ccRCC) by co-expression analysis

Gang Wang,Guang Zeng,Guofeng Qian,Liang Chen,Lushun Yuan,Mengxin Lu,Xiaolong Wang,Xinghuan Wang,Xinyue Cao,Xuefeng Liu,Yu Xiao

Activation of Central Alpha 7 Nicotinic Acetylcholine Receptor Reverses Suppressed Immune Function of T Lymphocytes and Protects Against Sepsis Lethality

Chao Ren,Li-xue Wang,Ning Dong,Shi-bin Wang,Xiu-hua Li,Yao Wu,Yong-ming Yao

Improvement of Animal Feed Additives of Ginkgo Leaves through Solid-state Fermentation using Aspergillus niger

Erzheng Su,Fuliang Cao,Jiahong Wang,Linguo Zhao,Wensheng Qin

Health risks associated with genetic alterations in internal clock system by external factors

Ghulam Nabi,Hongwei Hou,Lunguang Yao,Pengfei Duan,Rabeea Siddique,Suliman Khan,Sunjeet Kumar,Wasim Sajjad

The prevalence of autism spectrum disorders in China: a comprehensive meta-analysis

Cai-Lan Hou,Chee H. Ng,Fei Wang,Fu-Jun Jia,Gabor S. Ungvari,Jian-Ping Lu,Li Lu,Ling Zhang,Shi-Bin Wang,Xiao-Lan Cao,Yu-Tao Xiang

Atg7 inhibits Warburg effect by suppressing PKM2 phosphorylation resulting reduced epithelial-mesenchymal transition

Brian P. O'Rourke,Fei Yi,Hongde Xu,Jingwei Liu,Liu Cao,Longyue L. Cao,Qiqiang Guo,Ting Liu,Wendong Guo,Wenyu Zhang,Xiang Dong,Xiaoyu Song,Yanling Feng,Yi Guan

Comparison of microRNA Profiles between Bovine Mammary Glands Infected with Staphylococcus aureus and Escherichia coli

Chu-Gang Mei,Lin-Sen Zan,Xing-Ping Wang,Zhuo-Ma Luoreng

Human Papillomavirus Types 16 and 18 Early-expressed Proteins Differentially Modulate the Cellular Redox State and DNA Damage

Alfredo Cruz-Gregorio,Claudia María García-Cuellar,Emilio Rojas,Joaquín Manzo-Merino,José Pedraza-Chaverri,Mahara Valverde,Marcela Lizano,María Alexandra Rodríguez-Sastre,María Cecilia Gonzaléz-García,Omar Noel Medina-Campos

Dioscin overcome TKI resistance in EGFR-mutated lung adenocarcinoma cells via down-regulation of tyrosine phosphatase SHP2 expression

Chih-Yi Chen,De-Wei Wu,Huei Lee,Lee Wang,Tzu-Chin Wu,Yao-Chen Wang

The metabonomics study of P-selectin glycoprotein ligand-1 (PSGL-1) deficiency inhibiting the progression of atherosclerosis in LDLR-/- mice

Binglin Li,Jia Wang,Lijing Wang,Quliang Gu,Xiaodong He,Xin Lu,Yongxia Yang

Disruption of Gen1 Causes Congenital Anomalies of the Kidney and Urinary Tract in Mice

Bin Guo,Chi Zhang,Herui Wang,Hong Xu,Jiaojiao Liu,Miao Han,Qian Shen,Sixian Xu,Ting Ni,Xiang Wang,Xiaoe Zhang,Xiaohui Wu,Xiaoting Zhu,Xiaowen Wang,Yaru Lian,Yuan Zhuang,Yunli Bi,Zengli Guo

Mycotoxin zearalenone exposure impairs genomic stability of swine follicular granulosa cells in vitro

Lan Li,Rui-Qian Zhang,Rui-Ying Wu,Shun-Feng Cheng,Tian-Yu Zhang,Wei Shen,Xi-Feng Zhang,Xiao-Feng Sun,Xue-Lian Liu,Yong Zhao

Tumor Necrosis Factor-α Induced Protein 8: Pathophysiology, Clinical Significance, and Regulatory Mechanism

Lei Zhang,Ran Liu,Ying-yi Luan,Yong-ming Yao

Generation of Cashmere Goats Carrying an EDAR Gene Mutant Using CRISPR-Cas9-Mediated Genome Editing

Dongjun Liu,Fei Hao,Hao Liang,Hui Wang,Wei Yan,Xiao Hu,Xiaocong Li,Xu Liu,Yingmin Wang

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