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Archive of "AAPS PharmSciTech".

ISSN Print: 1530-9932

ISSN Online:

Website: https://www.ncbi.nlm.nih.gov/pmc/journals/793/

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Small-Scale Assays for Studying Dissolution of Pharmaceutical Cocrystals for Oral Administration

John Comer,Karl J. Box,Nikoletta Fotaki,Rebeca Ruiz,Robert Price,Robert Taylor,Shyam Karki

Ilex paraguariensis Pellets from a Spray-Dried Extract: Development, Characterization, and Stability

Eloir Paulo Schenkel,Fagner Magalh？es,Francini K. J. Yatsu,Greice S. Borghetti,Humberto G. Ferraz,Valquiria L. Bassani

Nanostructured Cubosomes in a Thermoresponsive Depot System: An Alternative Approach for the Controlled Delivery of Docetaxel

Jayashree B. Taksande,Nilesh R. Rarokar,Nishikant A. Raut,Pramod B. Khedekar,Suprit D. Saoji,Vivek S. Dave

Encapsulation of Mentha Oil in Chitosan Polymer Matrix Alleviates Skin Irritation

Apurva Jakhmola,Archana Kanaujia,Debabrata Chanda,Dharmendra Saikia,Kuldeep Singh Yadav,Nidhi Mishra,Priyam Sinha,Vineet Kumar Rai

Process and Method Variability Modeling to Achieve QbD Targets

Mark Alasandro

Pharmaceutical Thermal Processing

Feng Zhang,Michael A. Repka

Challenges and Strategies in Thermal Processing of Amorphous Solid Dispersions: A Review

James W. McGinity,Justin S. LaFountaine,Robert O. Williams, III

Conjugation of Hot-Melt Extrusion with High-Pressure Homogenization: a Novel Method of Continuously Preparing Nanocrystal Solid Dispersions

Andreas Gryczke,Dipesh Neupane,Hemlata Patil,Jiannan Lu,Karl Kolter,Michael A. Repka,Nigel Langley,Roshan V. Tiwari,Sanjay R. Mishra,Soumyajit Majumdar,Xin Feng,Xingyou Ye

Development of an Ointment Formulation Using Hot-Melt Extrusion Technology

Abhijeet Maurya,Ajinkya M. Bhagurkar,Hemlata Patil,Michael A. Repka,Muralikrishnan Angamuthu,Roshan V. Tiwari,S. Narasimha Murthy,Santanu Kundu,Seyed Meysam Hashemnejad

Novel Controlled Release Polymer-Lipid Formulations Processed by Hot Melt Extrusion

Dennis Douroumis,Devyani Amin,Mohammed Maniruzzaman,Muhammad T. Islam,Sheelagh Halsey

Improved Skin Penetration Using In Situ Nanoparticulate Diclofenac Diethylamine in Hydrogel Systems: In Vitro and In Vivo Studies

Biswadip Sinha,Biswajit Mukherjee,Sarita Banerjee,Soma Sengupta

Nanosuspensions Containing Oridonin/HP-β-Cyclodextrin Inclusion Complexes for Oral Bioavailability Enhancement via Improved Dissolution and Permeability

Baojian Wu,Tianpeng Zhang,Xingwang Zhang,Yali Lan

pH-Dependent Solubility and Dissolution Behavior of Carvedilol—Case Example of a Weakly Basic BCS Class II Drug

Aiman Abbas,Areeg Awadallah,Jihan Al Sayyad,Ola Tarawneh,Rania Hamed,Sami Nazzal,Suhair Sunoqrot,Tamadur AlBaraghthi

Preparation and In Vitro–In Vivo Evaluation of Sustained-Release Matrix Pellets of Capsaicin to Enhance the Oral Bioavailability

Dongmei Jiang,E. Omari-Siaw,Jiangnan Yu,Miaomiao Wang,Shuang Lu,Weiming Zhang,Ximing Xu,Ya Zhang,Zhimin Huang

Development and Optimization of a Novel Prolonged Release Formulation to Resist Alcohol-Induced Dose Dumping

Balaramesha Chary Rallabandi,Chaitanya Yogananda Gujjar,Ramesh Gannu,Vallabh Subashrao Deulkar

Use of Polyvinyl Alcohol as a Solubility Enhancing Polymer for Poorly Water-Soluble Drug Delivery (Part 2)

Chris Brough,Daniel Ellenberger,Dave A. Miller,Dieter Lubda,Robert O. Williams, III

Hot Melt Extrusion: Development of an Amorphous Solid Dispersion for an Insoluble Drug from Mini-scale to Clinical Scale

Anjali M. Agrawal,Ewa Zimny,Mayur S. Dudhedia

Twin Screw Extruders as Continuous Mixers for Thermal Processing: a Technical and Historical Perspective

Charlie Martin

Acceptance Probability (Pa) Analysis for Process Validation Lifecycle Stages

Daniel Alsmeyer,Francesco Munaretto,Maksuda Hye,Pradeep Sanghvi,Shu Chen

A New Extrudable Form of Hypromellose: AFFINISOL？ HPMC HME

James W. McGinity,Justin M. Keen,Kevin P. O’Donnell,Mark A. Rickard,Robert O. Williams, III,Siyuan Huang

Melt-Extruded Eudragit？ FS-Based Granules for Colonic Drug Delivery

Feng Zhang

QbD-Enabled Development of Novel Stimuli-Responsive Gastroretentive Systems of Acyclovir for Improved Patient Compliance and Biopharmaceutical Performance

Anterpreet Kaur,Babita Garg,Rajneet Kaur Khurana,Sarwar Beg,Shashi Dhiman

Assessment of the Dissociation Energetics of Some Selected Ligand Drugs Bound on Human Serum Albumin by Differential Scanning Calorimetry

Damrongsak Faroongsarng

Development of Solid Self-Emulsifying Formulation for Improving the Oral Bioavailability of Erlotinib

Cheol Moon,Chul Soon Yong,Duy Hieu Truong,Han-Gon Choi,Hee Hyun Lee,Ju Yeon Choi,Thiruganesh Ramasamy,Tuan Hiep Tran

Investigation of Thermal and Viscoelastic Properties of Polymers Relevant to Hot Melt Extrusion, IV: Affinisol？ HPMC HME Polymers

Abu T. M. Serajuddin,Nayan Solanki,Simerdeep Singh Gupta

Optimising Drug Solubilisation in Amorphous Polymer Dispersions: Rational Selection of Hot-melt Extrusion Processing Parameters

David S. Jones,Gavin P. Andrews,Shu Li,Yiwei Tian

Taste Masking of Griseofulvin and Caffeine Anhydrous Using Kleptose Linecaps DE17 by Hot Melt Extrusion

Abhishek Juluri,Carmen Popescu,Chetan Kumar P,Leon Zhou,Manjeet B. Pimparade,Michael A. Repka,Reena N. Murthy,S. Narasimha Murthy,Vanaja K. Gowda

Development of an Abuse- and Alcohol-Resistant Formulation Based on Hot-Melt Extrusion and Film Coating

Eva Roblegg,Johannes Khinast,Johannes M. Fischer,Karlheinz Breinh？lter,Nicole Jedinger,Simone Schrank

Glutamine-Loaded Liposomes: Preliminary Investigation, Characterization, and Evaluation of Neutrophil Viability

Bárbara Nayane Rosário Fernandes Souza,Cláudia Jacques Lagranha,Fábio Fidélis Almeida,Larissa Chaves Costa,Mariane Cajubá de Britto Lira-Nogueira,Nereide Stela Santos-Magalh？es,Pabyton Gon？alves Cadena

Solid-State Characterization and Interconversion of Recrystallized Amodiaquine Dihydrochloride in Aliphatic Monohydric Alcohols

Jittima Chatchawalsaisin,Wiriyaporn Sirikun

Microparticles Containing Curcumin Solid Dispersion: Stability, Bioavailability and Anti-Inflammatory Activity

C. C. C. Teixeira,G. E. P. Souza,L. A. P. Freitas,L. M. G. Antunes,L. M. Mendon？a,M. M. Bergamaschi,R. H. C. Queiroz

Design and Evaluation of a Novel Felbinac Transdermal Patch: Combining Ion-Pair and Chemical Enhancer Strategy

Liang Fang,Nannan Liu,Tian Song,Wenting Song

A Quality by Experimental Design Approach to Assess the Effect of Formulation and Process Variables on the Extrusion and Spheronization of Drug-Loaded Pellets Containing Polyplasdone？ XL-10

Anuja M. Rane,Kalyan K. Saripella,Nikhil C. Loka,Rama Mallipeddi,Steven H. Neau

Development, Optimization, and Characterization of PEGylated Nanoemulsion of Prostaglandin E1 for Long Circulation

Daozhou Liu,Huijing Hu,Miao Liu,Siyuan Zhou,Ying Cheng

Improved Aqueous Solubility and Antihypercholesterolemic Activity of Ezetimibe on Formulating with Hydroxypropyl-β-Cyclodextrin and Hydrophilic Auxiliary Substances

Kale Mohana Raghava Srivalli

Drop-on-Demand System for Manufacturing of Melt-based Solid Oral Dosage: Effect of Critical Process Parameters on Product Quality

Arun Giridhar,El？in I？ten,Gintaras V. Reklaitis,Zoltan K. Nagy

Thermal Processing of PVP- and HPMC-Based Amorphous Solid Dispersions

Chris Brough,Dave A. Miller,James W. McGinity,Justin S. LaFountaine,Leena Kumari Prasad,Robert O. Williams, III

Use of Polyvinyl Alcohol as a Solubility-Enhancing Polymer for Poorly Water Soluble Drug Delivery (Part 1)

Chris Brough,Dave A. Miller,Dieter Lubda,Justin M. Keen,Robert O. Williams, III,Shawn A. Kucera

Development of Tablet Formulation of Amorphous Solid Dispersions Prepared by Hot Melt Extrusion Using Quality by Design Approach

Anjali Agrawal,Edward Povilaitis,Ewa Zimny,Kevin Shepard,Li Zhong,Mayur Dudhedia,Weibin Deng

Gastroretentive Matrix Tablets of Boswellia Oleogum Resin: Preparation, Optimization, In Vitro Evaluation, and Cytoprotective Effect on Indomethacin-Induced Gastric Ulcer in Rabbits

Elham Abdelmonem Mohamed,Farid Abd-Elreheim Badria,Irhan Ibrahim Abu Hashim,Rehab Mohammad Yusif

Construction and Validation of Binary Phase Diagram for Amorphous Solid Dispersion Using Flory–Huggins Theory

Krishna Bansal,Seema Thakral,Uttam Singh Baghel

An Intensified Vibratory Milling Process for Enhancing the Breakage Kinetics during the Preparation of Drug Nanosuspensions

Ecevit Bilgili,Lu Zhang,Meng Li,Rajesh N. Davé

Effects of Temperature and Humidity on Laser Diffraction Measurements to Jet Nebulizer and Comparison with NGI

Junhua Hu,Rui Zhang,Shuyao Zhan,Wen Tan,Xinghan Song

Compression-Coated Tablet for Colon Targeting: Impact of Coating and Core Materials on Drug Release

Biswanath Sa,Siddhartha Maity

Coatings of Eudragit？ RL and L-55 Blends: Investigations on the Drug Release Mechanism

Claudia S. Leopold,Robert Wulff

Assessing Mixing Quality of a Copovidone-TPGS Hot Melt Extrusion Process with Atomic Force Microscopy and Differential Scanning Calorimetry

Anthony Pecora,James DiNunzio,Louis S. Crocker,Matthew S. Lamm,Nazia N. Khawaja

Hot-Melt Extrusion: from Theory to Application in Pharmaceutical Formulation

Hemlata Patil,Michael A. Repka,Roshan V. Tiwari

Nanoparticle-Based Topical Ophthalmic Gel Formulation for Sustained Release of Hydrocortisone Butyrate

Ashim K. Mitra,Dhananjay Pal,Hoang M. Trinh,Vibhuti Agrahari,Xiaoyan Yang,Ye Sheng

Quality-by-Design II: Application of Quantitative Risk Analysis to the Formulation of Ciprofloxacin Tablets

H. Gregg Claycamp,Raafat Fahmy,Ravikanth Kona,Stephen W. Hoag

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