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Archive of "Acta Pharmaceutica Sinica. B".

ISSN Print: 2211-3835

ISSN Online:

Website: https://www.ncbi.nlm.nih.gov/pmc/journals/2814/

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Matrine attenuates oxidative stress and cardiomyocyte apoptosis in doxorubicin-induced cardiotoxicity via maintaining AMPKα/UCP2 pathway

Can Hu,Haiming Wu,Lingli Li,Ning Zhang,Wei Deng,Wenying Wei,Xin Zhang,Zhenguo Ma

Up-regulation of glycolipid transfer protein by bicyclol causes spontaneous restriction of hepatitis C virus replication

Hu Li,Jianrui Li,Jinhua Chen,Junjun Cheng,Lihua Wang,Limin Zhao,Meng-Hao Huang,Pei Lan,Qiang Li,Rong Xue,Wenjing Li,Xiaoqin Lv,Yongfeng Yang,Zhouyi Wu,Zonggen Peng

Cardamonin from a medicinal herb protects against LPS-induced septic shock by suppressing NLRP3 inflammasome

Guang Xu,Jiabo Wang,Ming Niu,Nan Qin,Ruisheng Li,Xiaohe Xiao,Xiaoyan Zhan,Youping Liu,Yuan Gao,Zhaofang Bai,Zhilei Wang

Multifunctional polymeric micelle-based chemo-immunotherapy with immune checkpoint blockade for efficient treatment of orthotopic and metastatic breast cancer

Jiaojie Wei,Jingdong Rao,Qin He,Rong Guo,Sheng Yin,Xian Tang,Xinlei Liu,Yang Long,Zhirong Zhang

Cholesterol-tuned liposomal membrane rigidity directs tumor penetration and anti-tumor effect

Dongkai Wang,Ejaj Ahmad,Hangyi Wu,Miaorong Yu,Sha Song,Shufang He,Wenyi Song,Yuan Liu,Yunqiu Miao,Zhuo Dai

Menthol-modified casein nanoparticles loading 10-hydroxycamptothecin for glioma targeting therapy

Caifang Gao,Chengli Ling,Jianming Liang,Jing Qin,Ruixiang Li,Weigen Lu,Ying Zhu,Zhekang Cheng

Marine sponges of the genus Stelletta as promising drug sources: chemical and biological aspects

Bastien Nay,Hong Wang,Ligong Yao,Min Yang,Qihao Wu,Yeke Ni

LSD1 inhibition suppresses the growth of clear cell renal cell carcinoma via upregulating P21 signaling

Baijun Dong,Jianfeng Wang,Jiwei Huang,Liangsong Zhu,Wei Xue,Wen Kong,Yiran Huang

Redox-sensitive prodrug nanoassemblies based on linoleic acid-modified docetaxel to resist breast cancers

Dan Liu,Liwen Zhao,Meng Li,Tao Zhang,Yongjun Wang,Yue Shu,Zhonggui He

Transformative hyaluronic acid-based active targeting supramolecular nanoplatform improves long circulation and enhances cellular uptake in cancer therapy

Dongyang Zhao,Haotian Zhang,Huicong Zhang,Jin Sun,Lu Xu,Lu Zhong,Qiming Kan,Qingsong Li,Yanying Liu,Yongjun Wang,Zhenbao Li

The effects of pH, surfactant, ion concentration, coformer, and molecular arrangement on the solubility behavior of myricetin cocrystals

Chao Hong,Guowen Li,Jiabin Sun,Jianying Wang,Lei Zhang,Mingyu Liu,Shuzhen Ren

Intestinal uptake of barley protein-based nanoparticles for β-carotene delivery

Guangyu Liu,Ying Zhou

Novel fluorescent probes of 10-hydroxyevodiamine: autophagy and apoptosis-inducing anticancer mechanisms

Chunquan Sheng,Guoqiang Dong,Na Liu,Shanchao Wu,Wannian Zhang

Overcoming chemotherapy resistance via simultaneous drug-efflux circumvention and mitochondrial targeting

Fengling Wang,Lian Li,Lijia Li,Minglu Zhou,Qiuyi Li,Xi Lin

Aurone derivatives as Vps34 inhibitors that modulate autophagy

Chung-Nga Ko,Dik-Lung Ma,Guodong Li,Jian-Bo Wan,Joshua William Boyle,Philip Wai Hong Chan,Vincent Kam Wai Wong,Wu Zeng

Inhibition of FOXO3a/BIM signaling pathway contributes to the protective effect of salvianolic acid A against cerebral ischemia/reperfusion injury

Guanhua Du,Haigang Wang,Haiguang Yang,Jinhua Wang,Li Li,Qimeng Zhou,Wen Zhang

Combinatorial mutation on the β-glycosidase specific to 7-β-xylosyltaxanes and increasing the mutated enzyme production by engineering the recombinant yeast

Fen Wang,Jin-Ling Yang,Jing-Jing Chen,Tian-Jiao Chen,Ting Gong,Wan-Cang Liu,Xiao Liang,Yan-Hua Wen

GLUT1-mediated effective anti-miRNA21 pompon for cancer therapy

Chao Li,Chen Jiang,Donghui Liang,Qin Guo,Qinjun Chen,Tao Sun,Wenxi Zhou,Yifei Lu,Yu Zhang,Yujie Zhang

Ablation of gut microbiota alleviates obesity-induced hepatic steatosis and glucose intolerance by modulating bile acid metabolism in hamsters

Bo Liu,George Liu,Huiying Liu,Lulu Sun,Min Ye,Qing Wu,Wei Kong,Xuemei Wang,Yuanyuan Pang

Small molecules for fat combustion: targeting obesity

Jingxin Liu,Yitao Wang

Hypocrellin A-based photodynamic action induces apoptosis in A549 cells through ROS-mediated mitochondrial signaling pathway

Lingyuan Guo,Robert J. Lee,Shanshan Qi,Shuqin Yu,Shuzhen Yan

Glycyrrhetinic acid binds to the conserved P-loop region and interferes with the interaction of RAS-effector proteins

Jin Tao,Shengnan Yang,Xiaoyao Ma,Xueyan Hu,Yuan Zhang,Yuanyuan Hou,Zhihua Wang

The epigallocatechin gallate derivative Y6 reverses drug resistance mediated by the ABCB1 transporter both in vitro and in vivo

Donghua Yang,Lijuan Liao,Pranav Gupta,Ruiqiang Zhao,Xiaohui Li,Yan Wen,Yingfang Fan,Yu-An Xie,Yuangang Su,Yunkai Zhang,Zhe-Sheng Chen,Zhenguang Huang

Discovery of a series of dimethoxybenzene FGFR inhibitors with 5H-pyrrolo[2,3-b]pyrazine scaffold: structure–activity relationship, crystal structural characterization and in vivo study

Bo Liu,Dongmei Zhao,Jing Ai,Jingkang Shen,Lanlan Li,Maosheng Cheng,Meiyu Geng,Peng Wei,Ruifeng Wang,Yinglei Gao,Yuchi Ma,Yuelei Chen,Zhiwei Qian

Biosynthesis of clinically used antibiotic fusidic acid and identification of two short-chain dehydrogenase/reductases with converse stereoselectivity

Guodong Chen,Hao Gao,Ikuro Abe,Jianming Lv,Shaoyang Li,Takayoshi Awakawa,Xinsheng Yao,Zhiqin Cao

Application of flash nanoprecipitation to fabricate poorly water-soluble drug nanoparticles

Jinsong Tao,Shing Fung Chow

Supersaturated polymeric micelles for oral silybin delivery: the role of the Soluplus–PVPVA complex

Chunliu Zhu,Ejaj Ahmad,Jinsong Ding,Miaorong Yu,Shuang Gong,Yi Feng

Drug nanoclusters formed in confined nano-cages of CD-MOF: dramatic enhancement of solubility and bioavailability of azilsartan

Caifen Wang,Guoqing Zhang,Jiwen Zhang,Li Wu,Liu Zhang,Ming Yang,Ruxandra Gref,Vikramjeet Singh,Wei Qin,Wei Zhang,Weifeng Zhu,Xiaoxiao Hu,Yuanzhi He

Editor Profiles: Guest Editors of Special Issue on Enhancement of Dissolution and Oral Bioavailability of Poorly Water-soluble Drugs

Jianping Qi,Wei Wu,Yi Lu

Development of carrier-free nanocrystals of poorly water-soluble drugs by exploring metastable zone of nucleation

Jianping Qi,Wei Wu,Xiaoting Ren,Yi Lu,Zongning Yin

Emerging transporter-targeted nanoparticulate drug delivery systems

Guangxuan Liu,Hongyan Su,Qian Liu,Shuo Liu,Yan Wang,Yue Wang

Recent advances of microneedles for biomedical applications: drug delivery and beyond

Jian Yang,Xinli Liu,Yunzhi Fu

Exploring the utility of the Chasing Principle: influence of drug-free SNEDDS composition on solubilization of carvedilol, cinnarizine and R3040 in aqueous suspension

Huiling Mu,Kirsten Graeser,ScheylaDaniela Siqueira J？rgensen,Thomas Rades

Cordycepin promotes browning of white adipose tissue through an AMP-activated protein kinase (AMPK)-dependent pathway

Chongming Wu,Guihong Qi,Jiaqi Yu,Xiaopo Zhang,Xiaoxue Cao,Xin Li,Yue Zhou

Efficient lung cancer-targeted drug delivery via a nanoparticle/MSC system

Haiyan Chen,Jimin Han,Ling Guo,Ruiyun Tian,Shan Wang,Wenpeng Guo,Xiaowei Zeng,Xusheng Wang,Yanjiang Han,Yaojiong Wu,Yu Jin

Bioactive A-ring rearranged limonoids from the root barks of Walsura robusta

Faliang An,Jun Luo,Minghua Yang,Xiaobing Wang

Secalonic acid D induces cell apoptosis in both sensitive and ABCG2-overexpressing multidrug resistant cancer cells through upregulating c-Jun expression

Fang Wang,Hong Zhang,Jianye Zhang,Liyan Huang,Liyang Tao,Xu Zhang

Small interfering RNA delivery to the neurons near the amyloid plaques for improved treatment of Alzheimer？s disease

Dongyu Sheng,Jinxu Cao,Kang Qian,Liuchang Wang,Peng Yang,Pengzhen Wang,Qian Guo,Shuting Xu,Wei Lu,Xiaoyao Zheng,Xiaoying Pang,Xinguo Jiang

Emodin alleviates cardiac fibrosis by suppressing activation of cardiac fibroblasts via upregulating metastasis associated protein 3

Baofeng Yang,Dan Xiao,Dmitri Shchekochikhin,Hongtao Diao,Lin Wen,Philipp Kopylov,Rui Wang,Tong Zhou,Xujuan Kang,Yong Zhang,Yuan Lin,Yujie Fu,Zhange Li,Zhixia Wang

Development of the triazole-fused pyrimidine derivatives as highly potent and reversible inhibitors of histone lysine specific demethylase 1 (LSD1/KDM1A)

Bin Yu,Bing Zhao,Dandan Shen,Fengzhi Suo,Hongmin Liu,Junwei Wang,Lina Ding,Liying Ma,Pengfei Geng,Taoqian Zhao,Xudong Sun,Yichao Zheng,Zhizheng Wang,Zhonghua Li,Zhongrui Li

Silibinin ameliorates hepatic lipid accumulation and oxidative stress in mice with non-alcoholic steatohepatitis by regulating CFLAR-JNK pathway

Jiaojiao You,Ting Zhai,Wei Xu,Yong Chen

Pharmacometabolomic prediction of individual differences of gastrointestinal toxicity complicating myelosuppression in rats induced by irinotecan

Jiaqing Chen,Wei Li,Xu Wang,Yin Huang,Yingtong Lv,Yiqiao Gao,Zunjian Zhang

Deep learning for in vitro prediction of pharmaceutical formulations

Qianqian Zhao,Xiaoshan Li,Yan Su,Yilong Yang,Zhuyifan Ye

In vitro and in vivo activity of d-serine in combination with β-lactam antibiotics against methicillin-resistant Staphylococcus aureus

Congran Li,Jiandong Jiang,Jing Pang,Qing Wang,Tongying Nie,Xi Lu,Xinxin Hu,Xinyi Yang,Xiukun Wang,Xue Li,Yan Q. Xiong,Yuemeng Lv

Interaction between human serum albumin and cholesterol-grafted polyglutamate as the potential carriers of protein drugs

Dehai Liang,Qiufen Zhang,Xiangxue Lyu

Develop a 3D neurological disease model of human cortical glutamatergic neurons using micropillar-based scaffolds

Cheng Chen,Danjun Fang,Fang Yuan,Kai-Heng Fang,Min Xu,Xin Dong,Xixiang Zhang,Yao Hu,Yu Huang

Regulation of microbiota—GLP1 axis by sennoside A in diet-induced obese mice

Jiamei Le,Juntao Luo,Weiping Jia,Xiaoying Zhang,Yong Zhang,Yongning Sun

Novel C-17 spirost protostane-type triterpenoids from Alisma？plantago-aquatica？with anti-inflammatory activity in？Caco-2？cells

Bang Yeon Hwang,Chen Liu,Jianqing Zhang,Jinjun Hou,Min Lei,Qinghao Jin,Shuai Yao,Wanying Wu,Xia Wang,Yong Huang

Safety and photochemotherapeutic application of poly(γ-glutamic acid)-based biopolymeric nanoparticle

Quoc-Viet Le,Young Bong Kim,Yu-Kyoung Oh

Recent progress and challenges in screening and characterization of UGT1A1 inhibitors

Jingjing Wu,Ling Yang,Moshe Finel,Xia Lv,Yangliu Xia

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