Total of 2590 articles.


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Aug 10, 2016Open    AccessArticle

Terbinafine versus itraconazole: a long-term, randomized, double-blind, clinical trial in chronic pulmonary aspergillosis. A pilote study

"Gianfranco Schiraldi", "Salvatore Lo Cicero", "Claudio Rossetti","Delia Colombo", "Michele Chiericozzi", "Fabio Colombo", "Maurizio Ferrarese", "Elvana Kola"," Luigi Allegra"
Background: The frequency of pulmonary aspergillosis has been increasing for decades. Standard oral treatment is associated with tolerability problems and interactions with commonly used medications. Present data suggest that terbinafine may be a useful alternative for chronic forms. Methods: A randomised, double-blind, multicentre trial compared terbinafine (500 mg b.i.d) with itraconazole (200 mg b.i.d.) with respect to successful outcomes for up to 6 months in 24 patients with chronic pu...

Pharmacology  Respiratory Medicine 

Aug 10, 2016Open    AccessArticle

Is there health inequity in Europe today? The ‘strange case’ of the application of an European regulation to cartilage repair

Roberto Beretta
An important regulation, issued by the European Community in 2008, regulates the authorisation and supervision of advanced therapy medicinal products (ATMP) and subsequent follow up in Europe. This law contains a Hospital Exemption clause, under which some hospitals in some countries can be exempted from the regulations governing ATMPs. The application of this regulation in Europe has resulted in differences in the costs of cell therapy for cartilage injuries in Germany compared with the co...

Pharmacology  Public Health  Orthopedics 

Aug 10, 2016Open    AccessArticle

The high cancer incidence in young people in Italy: do genetic signatures reveal their environmental causes?

Ruggero Ridolfi
The increased incidence of cancer in children and adolescents registered in Italy in the last few decades is one of the highest amongst Western countries. The causes are difficult to identify, but recent daily news and some epidemiological surveys, such as the ‘Sentieri’ study, suggest that environmental pollution has an important role. In the past 20 years, epigenetic studies have described how the changes induced by the cell microenvironment on the non-coding parts of the genome can heavi...

Public Health  Epidemiology  Health Policy  Global Health  Environmental Sciences 

Aug 10, 2016Open    AccessArticle

Psychosocial risks within prison service

Giuseppe Ferrari
We aimed to identify the psychosocial risks that penitentiary police officers face. To do so, we developed the police stress risk questionnaire–prison (PSrQ–p), a questionnaire for psychosocial risk assessment at workplace, consisting of 22 items that investigated five macro dimensions: isolation, social image, firearms license, variety of work and roles/responsibilities. We tested this tool on a sample of 1,346 subjects, and testing is on-going. From the data obtained, we confirmed the hyp...

Psychiatry & Psychology  Public Health  Health Policy  Global Health 

Aug 10, 2016Open    AccessArticle

Workplace conflicts and psychological work-related injuries: our experience in Italy

Giuseppe Taino, Andrea Battaglia, Marcello Imbriani
In Europe, all countries regularly recognise mental disorders as workplace accidents (mainly post-traumatic stress disorders). However, there has been little emphasis on this emerging issue in Italy. Our discussion focuses on a recent case report regarding an employee who was affected by an acute anxiety disorder after a common workplace conflict with a coworker. Given that prolonged and unresolved relationship conflicts may result in more extreme forms of conflict known as workplace bullying, r...

Psychiatry & Psychology  Public Health  Health Policy  Global Health 

Aug 10, 2016Open    AccessArticle

Spiritual well-being in the 21st century: it’s time to review the current WHO’s health definition?

Francesco Chirico
Over the years, some critics argue that the dimension of spiritual well-being was missing from the World Health Organization’s (WHO) definition of health. Nevertheless, although the WHO’s definition has been criticized over the past 60 years, it has never been adapted. Spiritual well-being should not be confused with psychological well-being. Moreover, spirituality, personal beliefs and religiousness are not synonymous. Spirituality has received much interest in health care services; it can...

Psychiatry & Psychology  Public Health  Health Policy  Global Health 

Aug 10, 2016Open    AccessArticle

Editorial: Welcome to the Journal of Health and Social Sciences

Francesco Chirico, Giuseppe Ferrari
Dear Readers, It gives us enormous pleasure to officially launch the inaugural issue of the Journal of Health and Social Sciences. The Journal is an interdisciplinary, open access journal that focuses on the medical and health sciences. Topics of interest to the journal include all branches of medicine and other disciplines related to health such as psychology, social sciences and public, occupational and environmental sciences. According to the World Health Organization’s definition, health is ...

Health Policy  Global Health 

Aug 10, 2016Open    AccessArticle

Autoimmune extraintestinal manifestations of Helicobacter pylori infection: A bundle of conflicts

Erkan Yula
It has been well-known that several microorganisms that have an effect on particular areas of the body might additionally have systemic sequelae. In the last ten years, various studies have been performed on the relationship between Helicobacter pylori infection and a variety of extra digestive illnesses including immunological, hematological, neurological disorders and different pathologies. It has been recommended that complicated interactions between bacterial and host genetic factors, as wel...

Allergy & Clinical Immunology  Infectious Diseases  Immunology  Rheumatology 

Jun 30, 2016Open    AccessArticle

MUDHARABAH PERSPEKTIF AVERROES (Studi Analisis Kitab Bidayat al-Mujtahid Wa Nihayat al-Muqtashid)

Abdul Mukti Thabrani
Tulisan ini akan menganalisa pemikiran Ibn Rusyd (Averroes), seorang pemikir, filosof, dan ulama besar asal Spanyol yang hidup pada 1126 – 1198 M, tentang konsep mudharabah dalam bidang fikih muamalah yang tertuang dalam karya monumentalnya yang terkenal sampai sekarang, Bidayat al-Mujtahid wa Nihayat al-Muqtashid. Pemikiran beliau dalam bidang ini ternyata masih sangat relevan dengan konteks kekinian, utamanya dalam bidang keuangan dan perbankan Islam secara umum yang diadaptasi oleh negara-neg...

Business Law  Business Theories  Economic System 
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Jun 30, 2016Open    AccessArticle

Antihepatotoxic efficacy of mushroom, Agaricus blazei murrill against carbon tetrachloride induced liver damage in male albino wistar rats

M. Muthulingam, S. Senthilmaran, V. Kurinji, N. Indra and S. Sethupathy
Mushrooms have a long history of use in folk medicine, and higher Basidiomycetes have become matters of great interest, due to their many-fold nutritional, medicinal, and pharmacological properties. Mushroom extracts are widely sold as nutritional supplements and touted as beneficial for health. Agaricus blazei is widely used for nonprescript, medicinal purposes, both as an edible mushroom and in the form of extracts. According to tradition, it helps against a variety of diseases, including canc...

Zoology 

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