Infections from parasitic nematodes (or roundworms) contribute to a significant disease burden and productivity losses for humans and livestock. The limited number of anthelmintics (or antinematode drugs) available today to treat these infections are rapidly losing their efficacy as multidrug resistance in parasites becomes a global health challenge. We propose an engineering approach to discover an anthelmintic drug combination that is more potent at killing wild-type Caenorhabditis elegans wor...

Neuroscience  Marine Biology  Toxicology  Taxonomy  Microbiology  Ecosystem Science  Biodiversity  Developmental Biology  Bioengineering  Environmental Sciences  Animal Behavior  Agricultural Science  Biotechnology  Computational Biology  Food Science & Technology  Parasitology  Plant Science  Synthetic Biology 

Doi:10.1126/sciadv.aao1254

In this study, total phenolic compounds, total flavonoid substances and total antioxidant capacities of dried darak dal？ (Dill=Anethumgraveolens L.) and basil (Ocimumbasilicum) stalks with seed grown in the central villages of Kastamonu province, to use in the production of Tarhana and sold in local markets were determined. Seeds and stalks were analyzed separately. The average total phenolic compound, total flavonoid substance and total antioxidant capacities for the darak dal？ were founded as ...

Toxicology  Nutrition 

Doi:/10.25279/sak.355048

Grewia asiatica L., is a species native to south Asia from Pakistan, east to Cambodia, cultivated primarily for its edible fruit and well-reputed for its diverse medicinal uses. Fruits are a rich source of nutrients such as proteins, amino acids, vitamins, and minerals and contain various bioactive compounds, like anthocyanins, tannins, phenolics and flavonoids. Different parts of this plant possess different pharmacological properties. Leaves have antimicrobial, anticancer, antiplatelet and ant...

Biological Chemistry  Cardiology  Toxicology  Photochemistry  Taxonomy  Medicinal Chemistry  Environmental Sciences  Agricultural Science  Genetics  Food Science & Technology  Nutrition  Analytical Chemistry  Biological Materials  Environmental Chemistry  Green Chemistry  Pharmacology  Public Health  Organic Chemistry  Evidence Based Medicine  Gastroenterology & Hepatology  Microbiology  Global Health  Biochemistry  Biodiversity  Biophysics  Biotechnology  Translational Medicine  Respiratory Medicine 

Doi:10.3390/molecules18032663

Rubus fruticosus L. is a shrub famous for its fruit called blackberry fruit or more commonly blackberry. The fruit has medicinal, cosmetic and nutritive value. It is a concentrated source of valuable nutrients, as well as bioactive constituents of therapeutic interest highlighting its importance as a functional food. Besides use as a fresh fruit, it is also used as ingredient in cooked dishes, salads and bakery products like jams, snacks, desserts, and fruit preserves. R. fruticosus contains vit...

Biological Materials  Diabetes & Endocrinology  Green Chemistry  Biological Chemistry  Evidence Based Medicine  Gastroenterology & Hepatology  Toxicology  Taxonomy  Clinical Trials  Biochemistry  Bioinformatics  Biophysics  Environmental Sciences  Agricultural Science  Food Science & Technology  Translational Medicine  Plant Science  Analytical Chemistry 

Doi:10.3390/molecules190810998