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Paracoccidioidomicose: freqüência, morfologia e patogênese de les?es tegumentares

DOI: 10.1590/S0365-05962007000500003

Keywords: epidemiology, mucous membrane, mycosis, paracoccidioidomycosis, skin manifestations.

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Abstract:

background: paracoccidioidomycosis is a highly prevalent systemic mycosis in brazil. the oral and cutaneous lesions are useful for diagnostic proposals and clinical follow-up. objective: to quantify and qualify skin lesions associated to active paracoccidioidomycosis and to correlate them with the clinical form and severity of cases. methods: an observational clinical study of cases was performed. patients were classified according to the clinical form, topographic distribution and morphology of skin lesions. results: a total of 152 patients classified as chronic form (adult type) (87.5%) or acute-subacute form (juvenile type) (12.5%) were studied. skin lesion was diagnosed in 61.2% of patients. there was no statistical correlation between presence of skin lesion and clinical form (p=1.000), nor between skin lesion and severity of disease (p=0.5607). there was statistical correlation between mucosal lesion and adult patients (p <0.001). the lesions were on the cephalic segment (47.6%), trunk (14.9%), upper limbs (14.9%), lower limbs (21.7%) and genital region (0.7%). the ulcerated lesions (42.8%) and infiltrative (26.6%) lesions prevailed. conclusion: the frequency of skin lesions and their morphology are useful for diagnosis of paracoccidioidomycosis. oral lesions in the acute-subacute form (juvenile type) are not common.

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