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Colorectal Cancer: Epidemiological, Clinical and Histopathological Aspects in Burundi

DOI: 10.4236/ojgas.2016.63011, PP. 83-87

Keywords: Colon Cancer, Adenocarcinoma, Rectal Cancer, Colorectal Cancer

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Abstract:

Colorectal cancer is a major cause of morbidity and mortality throughout the world. There is no study about colorectal cancer in our country. The aim of the study was to assess epidemiological, clinical, therapeutic and histological aspects of colorectal cancer over a 10-year period (1999-2008) in Kamenge university hospital, Bujumbura, Burundi, by a descriptive retrospective study. A total of 37 cases of colorectal cancer, 22 males (59.5%) and 15 females (40.5%), mean age 50.8 years, were retrieved over the period of the study. The colorectal cancer was revealed by a rectal bleeding in 21 patients (56.8%) and an occlusive syndrome in 5 patients (13.5%). All patients underwent surgery. According to Dukes’ stages: 27% were A, 27% B, 19% C and 27% stage D. Histopathologically, 18 cases (46.7%) were differentiated adenocarcinoma, 14 cases (37.8%) undifferentiated adenocarcinoma, 2 cases of lymphoma and 2 cases of leiomyosarcoma. All patients underwent surgery. The hospitalization stay was a mean of 27 days. The prognosis was poor with a mortality rate of 13.5% in the hospital. In conclusion, colorectal cancer deserves awareness as a public health problem in our country.

References

[1]  Boyle, P. and Ferlay, J. (2005) Mortality and Survival in Breast and Colorectal Cancer. Nature Clinical Practice Oncology, 2, 424-425.
http://dx.doi.org/10.1038/ncponc0288
[2]  Parkin, D., Bray, F. and Ferlay, J. (2006) Global Cancer Statistics, 2002. CA: A Cancer Journal for Clinicians, 55, 74-108.
http://dx.doi.org/10.3322/canjclin.55.2.74
[3]  Boyle, P. and Langman, J.S. (2000) ABC of Colorectal Cancer: Epidemiology. BMJ, 321, 805-808.
http://dx.doi.org/10.1136/bmj.321.7264.805
[4]  Ferlay, J., Shin, H., Bray, F., Forman, D., Mathers, C. and Parkin, D.M. (2010) Estimates of Worldwide Burden of Cancer in 2008: GLOBOCAN 2008. International Journal of Cancer, 127, 2893-2917.
http://dx.doi.org/10.1002/ijc.25516
[5]  Diallo Owono, F.K., Nguema Mve, R., Ibaba, J.R., Mihindou, C. and Ondo N’dong, F. (2011) Aspects épidemiolo- giques et diagnostiques des cancers colorectaux à Libreville (Gabon). Medicine Tropical, 71, 605-607.
[6]  Mohammed, A.Z., Edino, S.T., Ochicha, O., Gwarzo, A.K. and Samaila, A.A. (2008) Cancer in Nageria: A 10-Year Analysis of the Kano Cancer Registry. Nigeria Journal of Medicine, 17, 280-284.
[7]  Darré, T., Amégbor, K., Bagny, A., Sewa, E., Tchangai, B., Sakiye, A., Allasani, F., Bouglouga, O., Lawson, A.L. and Napo-Koura, G. (2014) Histo-Epidemiological Profile of the Colorectal Cancers in Togo. Journal Africain d’Hépato- Gastroentérologie, 8, 226-229.
[8]  Kadende, P., Engels, D., Ndoricimpa, J., Ndabaneze, E., Habonimana, D., Marerwa, G., Bigirimana, V., Bazira, L. and Aubry, P. (1990) Les cancers digestifs au Burundi: premiers résultats d’une enquête menée à Bujumbura. Médecine d’Afrique Noire, 37, 552-562.
[9]  Haggar, F.A. and Boushey, R.P. (2009) Colorectal Cancer Epidemiology: Incidence, Mortality, Survival, and Risk Factors. Clinics in Colon and Rectal Surgery, 22, 91-97.
http://dx.doi.org/10.1055/s-0029-1242458
[10]  Gaudre, N., Ly, M., Badiaga, Y., Dembele, A.K., Bathily, M., Kone, A., Diallo, Y.L. and Diallo, D.A. (2013) Epidemiological and Clinical Features of Colorectal Cancer at the Hematology and Oncology Ward of Point G in Bamako, Mali, from 2005 to 2011: 113 Cases. Mali Médicale, 28, 32-36.
[11]  Roncucci, L. and Mariani, F. (2015) Prevention of Colorectal Cancer: How Many Tools Do We Have in Our Basket? European Journal of Internal Medicine, 26, 752-756.
[12]  Center, M.M., Jemal, A., Smith, R.A. and Ward, E. (2009) Worldwide Variations in Colorectal Cancer. CA: A Cancer Journal for Clinicians, 59, 366-378.
http://dx.doi.org/10.3322/caac.20038
[13]  Irabor, D. and Adedeji, O.A. (2009) Colorectal Cancer in Nigeria: 40 Years on. A Review. European Journal of Cancer Care, 18, 110-115.
http://dx.doi.org/10.1111/j.1365-2354.2008.00982.x

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