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Jun 05, 2025Open Access
Despite Parkinson’s Disease (PD) typically being diagnosed after 80% of dopaminergic neurons are lost, evidence suggests that many patients exhibit early symptoms and frequently utilize emergency department (ED) services years before formal diagnosis. Here we examine the untapped potential of EDs in early PD recognition and intervention. Analysis of nearly 14,000 PD patients from two major healthcare systems revealed that 74% visited the ED or urgent care in the two years preceding diagnosis, ye...
Apr 30, 2025Open Access
Objective: This research aimed to investigate the effects of hearing aids(HAs) on sound localization in noisy environment for individuals with unilateral hearing loss(UHL). Method: The study used an experimental approach with 43 participants (22 with UHL, 21 with normal hearing). Hearing thresholds were measured at 500 - 4000 Hz using pure-tone audiometry. Sound localization experiments were conducted in a 2 m × 2 m room with five loudspeakers arranged in a semi...
Apr 24, 2025Open Access
Objective: The aim of this study is to investigate the awareness and compliance of healthcare professionals to report notifiable diseases at the University Hospital of Casablanca. Methods: A descriptive cross-sectional study was carried out in the university hospital. A self administered questionnaire was used to collect data. It covers socio-demographic characteristics of participants and their knowledge about notifiable diseases, reporting procedures, and their attitudes towards MDR cases. Res...
Apr 23, 2025Open Access
This cross-sectional study investigates the relationship between climate change concerns and sickle cell disease (SCD) screening intentions among 392 single individuals (aged 14 - 35) in Kinshasa, DRC. Data was collected using a questionnaire adapted from a previous study, and analyzed using descriptive statistics and logistic regression. The study found that knowledge about SCD, heat stress, exposure to extreme weather events, and climate change anxiety were significantly associated with SCD sc...
Apr 17, 2025Open Access
Lithium has long been established as a first-line mood stabilizer in the treatment of bipolar disorder and treatment-resistant depression. In addition to its psychiatric applications, lithium has demonstrated neuroprotective properties through its influence on neurotransmitter regulation, neuroplasticity, inflammation, and oxidative stress. Objective: This narrative review aims to provide a comprehensive analysis of lithium’s role in mental health, focusing on its clinical efficacy, underlying n...
Apr 11, 2025Open Access
Introduction: Self-medication is widespread throughout the world, especially in developing countries. It is at the root of very harmful health consequences. This study was therefore conducted to determine its prevalence and identify the factors that explain this practice among children under 5 years of age, with a view to finding appropriate solutions. Methods: A cross-sectional analytical study was conducted in the City of Mwene-Ditu from July to August 2022. T...
Mar 31, 2025Open Access
Introduction: Alcohol misuse among university students remains a significant public health concern despite the existence of various interventions, policies, and laws aimed at addressing the issue. To better understand the situation, this scooping review aimed to assess the knowledge of alcohol consumption, perceived influencing factors, and prevalence of alcohol misuse among university students. Method: Meta-analysis was employed to synthesize data from several ...
Mar 26, 2025Open Access
Background: Human Papillomavirus is a sexually transmitted aetiologic agent causing cervical carcinoma. Human Papillomavirus vaccination is a novel primary prevention initiative to reduce the prevalence of cervical cancer globally. For this altruistic effort to succeed, it is imperative to determine the knowledge and willingness of parents to present their adolescent girls for vaccination before being sexually active. Methods: A review of 7 peer-reviewed studies...
Mar 25, 2025Open Access
Background: Malaria is the leading cause of hospital admission in Africa and constitutes the greatest disease burden in the region. More than one hundred nations are affected worldwide with children and pregnant women being mostly vulnerable. Children under the age of five years suffer severe forms. Malaria is said to be severe when the acute illness is associated with a life-threatening event(s). Several organ systems including the kidney can be involved. In most cases, s...
Mar 03, 2025Open Access
Context: Vonoprazan fumarate is the first-in-class innovative P-CAB (potassium-competitive acid blocker) authorized and launched in the Bangladeshi pharmaceutical market in June 2023. There is no study yet on the pharmaceutical quality of Vonoprazan fumarate products manufactured and marketed in Bangladesh. Systematic assessment of pharmaceutical quality parameters is a crucial part of the continuous quality improvement and monitoring of pharmaceutical products. It is also an ou...
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