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Feb 25, 2019Open    AccessArticle

Inhibition of Autophagy Attenuated Cell Damage after OGD/R in SH-SY5Y Cells by Down-Regulating AMPK-Mediated Autophagy Signaling Pathway

Yanxue Zhang, Hongyun Li
Background: Activation of autophagy becomes a new therapeutic target for the treatment of stroke. The aim of this study was to observe the role of autophagy in the model of glucose-oxygen deprivation reoxygenation (OGD/R) in SH-SY5Y cells by interfering with AMPK-mediated autophagy signaling pathway. Methods: The effects of autophagy on OGD/R injury in SH-SY5Y cells were investigated by evalua

Dec 28, 2018Open    AccessArticle

Post-Stroke Depression at Teaching Hospital Center of Libreville

I. A. Camara, C. M. Coulibaly, N. Diouf Mbourou, P. M. Gnigone, G. A. G. Mambila Matsalou, A. Nsounda Mandzela, L. Oura, J. Nyangui Mapaga, U. D. Kombila, M. M. Moubecka, P. N. Kouna
Introduction: Post-stroke depression occurs in a context of stroke characterized by sadness, loss of interest, feelings of guilt, loss of appetite, a feeling of tiredness, and a lack of concentration. Material and Methods: We conducted a descriptive cross-sectional study from January 1, 2013 to September 30, 2016. For the diagnosis of post-stroke depression, neuropsychological tests (DSM-IV and MADRS) were used. The collection app

Dec 04, 2018Open    AccessArticle

Serum Neopterin as a Novel Marker for Carotid Artery Stenosis in Community Subjects

Huanquan Liao, Zhichao Yan, Hongxuan Wang, Hua Hong
Background: Carotid artery stenosis (CAS) is one of the major high-risk mechanisms of stroke. Neopterin, an immune modulator secreted by macro-phages, has been reported to be elevated in patients with cerebrovascular dis-ease. However, an association between serum neopterin level and CAS has not been firmly established. Objective: To investigate the cross-sectional relation-ship between serum neopterin levels and CAS assessed by u

Oct 30, 2018Open    AccessArticle

Efficacy of a Combination of Tanacetum parthenium, 5-Hydroxy Tryptophan and Magnesium (Aurastop) in the Prevention of High Frequency Migraine with Aura

Giorgio Dalla Volta, Paola Zavarise, Laura Perego, Alessandro Pezzini
Object: To verify the efficacy and safety of the new combination of Tanacetum parthenium 150 mg, 5-hydrossitriptophan (5-HTTP) 20 mg and magnesium 185 mg (Aurastop) in the prophylactic treatment of high frequency migraine with aura (MWA). According to the international headache classification (IHCD 3 beta version) the aura p

Aug 10, 2018Open    AccessArticle

Variations of Musculocutaneous Nerve Combined with High Bifurcation of the Brachial Artery

Xiaoli Chen, Chengkai Fu, Chunxu Guo, Jian Wang, Ze Jiang, Lina Leng, Daowen Si
During a routine dissection of the right upper limb of a 65-year-old male cadaver whose death is not clear, we found two anatomical abnormalities on the musculocutaneous nerve and brachial artery on the same arm. First, the musculocutaneous nerve derived from the lateral fascicles of brachial plexus by two branches. Second, the brachial artery emitted the radial and ulnar arteries at the level of 1/3 proximal upp

Aug 06, 2018Open    AccessArticle

Efficacy of a Combination of Tanacetum parthenium, 5-Hydroxy Tryptophan and Magnesium (Aurastop) in Episodic Migraine Prevention: A Multicentric Observational Study

Federico Mainardi, Paola Merlo, Ferdinando Maggioni, Giorgio Zanchin, Giorgio Dalla Volta
Objective: To verify the efficacy and safety of the new combination of Tanacetum parthenium 150 mg, 5-hydrossitriptophan (5-HTTP) 20 mg and magnesium 185 mg (Aurastop) in the prophylactic treatment of episodic migraine without aura (MO). Methods: Eighty patients suffering from MO for at least 6 months with a monthly frequency of 3 to 8 attacks and 4 to12 headache days, were enrolled in this open study and treated with Aurastop twi

Jun 06, 2018Open    AccessArticle

One Neglected Yawning Function like Slow Wave Sleep: The Hypothetic Neurovascular Regulation from Mouth to Eye Driven by Expiration

Zi-Jian Cai
In this article, it is considered that the mechanism of yawning function is cor-relative to sleep. It was revealed from the electrophysiological studies that the slow wave sleep (SWS) was characterized as decrease in excitation from inspir-atory motoneurons more than from expiration, manifesting the expiratory activity dominating in SWS. To analogize yawning to SWS, herein it is only considered the expirat

Aug 08, 2017Open    AccessArticle

A Novel Surgical Approach to Traumatic Intracranial Epidural Hematoma

David Shrestha, Liang Feng
Objective: Traumatic intracranial epidural hematoma is considered to be the serious complication of head injury requiring appropriate evaluation and surgical intervention. Although craniotomy provides an effective evacuation of the hematoma, there is an insufficient data to support one particular surgical treatment method. The objective of this study is to address the effectiveness of Urokinase instillation via single b

Jul 12, 2017Open    AccessArticle

The Cholinergic-Regulated Thalamocortical Imagining as Mind Differentiated in Two Phases of Sleep: A View from the Guangdong People

Zi-Jian Cai
Recently, many achievements on neural sciences have been made by the people in television, such as the adipose cause of male hypothalamic aging, and so on. In this article, it is reported that, on June 17 this year in evening in television, the people in Guangdong attending the Opening Ceremony of BRICS Games there suggested that the cholinergic-regulated thalamocortical activation would result in the cortical imagin

Jun 08, 2017Open    AccessArticle

A Combination of Tanacetum parthenium, Griffonia simplicifolia and Magnesium (Aurastop) as Symptomatic Acute Treatment for Migraine Aura: A Retrospective Cohort Study

Paola Zavarise, Giorgio Dalla Volta
Background: effective treatments for migraine aura and related symptoms are not yet well established. In the last years, several herbal and/or nutraceutical preparations have been proposed as potential treatment. We report the results of a retrospective analysis on the synergistic effect of three nutraceutical components (Tanacetum p