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Dec 04, 2018Open    AccessArticle

Serum Neopterin as a Novel Marker for Carotid Artery Stenosis in Community Subjects

Huanquan Liao, Zhichao Yan, Hongxuan Wang, Hua Hong
Background: Carotid artery stenosis (CAS) is one of the major high-risk mechanisms of stroke. Neopterin, an immune modulator secreted by macro-phages, has been reported to be elevated in patients with cerebrovascular dis-ease. However, an association between serum neopterin level and CAS has not been firmly established. Objective: To investigate the cross-sectional relation-ship between serum neopterin levels and CAS assessed by u

Oct 30, 2018Open    AccessArticle

Efficacy of a Combination of Tanacetum parthenium, 5-Hydroxy Tryptophan and Magnesium (Aurastop) in the Prevention of High Frequency Migraine with Aura

Giorgio Dalla Volta, Paola Zavarise, Laura Perego, Alessandro Pezzini
Object: To verify the efficacy and safety of the new combination of Tanacetum parthenium 150 mg, 5-hydrossitriptophan (5-HTTP) 20 mg and magnesium 185 mg (Aurastop) in the prophylactic treatment of high frequency migraine with aura (MWA). According to the international headache classification (IHCD 3 beta version) the aura p

Aug 10, 2018Open    AccessArticle

Variations of Musculocutaneous Nerve Combined with High Bifurcation of the Brachial Artery

Xiaoli Chen, Chengkai Fu, Chunxu Guo, Jian Wang, Ze Jiang, Lina Leng, Daowen Si
During a routine dissection of the right upper limb of a 65-year-old male cadaver whose death is not clear, we found two anatomical abnormalities on the musculocutaneous nerve and brachial artery on the same arm. First, the musculocutaneous nerve derived from the lateral fascicles of brachial plexus by two branches. Second, the brachial artery emitted the radial and ulnar arteries at the level of 1/3 proximal upp

Aug 06, 2018Open    AccessArticle

Efficacy of a Combination of Tanacetum parthenium, 5-Hydroxy Tryptophan and Magnesium (Aurastop) in Episodic Migraine Prevention: A Multicentric Observational Study

Federico Mainardi, Paola Merlo, Ferdinando Maggioni, Giorgio Zanchin, Giorgio Dalla Volta
Objective: To verify the efficacy and safety of the new combination of Tanacetum parthenium 150 mg, 5-hydrossitriptophan (5-HTTP) 20 mg and magnesium 185 mg (Aurastop) in the prophylactic treatment of episodic migraine without aura (MO). Methods: Eighty patients suffering from MO for at least 6 months with a monthly frequency of 3 to 8 attacks and 4 to12 headache days, were enrolled in this open study and treated with Aurastop twi

Jun 06, 2018Open    AccessArticle

One Neglected Yawning Function like Slow Wave Sleep: The Hypothetic Neurovascular Regulation from Mouth to Eye Driven by Expiration

Zi-Jian Cai
In this article, it is considered that the mechanism of yawning function is cor-relative to sleep. It was revealed from the electrophysiological studies that the slow wave sleep (SWS) was characterized as decrease in excitation from inspir-atory motoneurons more than from expiration, manifesting the expiratory activity dominating in SWS. To analogize yawning to SWS, herein it is only considered the expirat

Aug 08, 2017Open    AccessArticle

A Novel Surgical Approach to Traumatic Intracranial Epidural Hematoma

David Shrestha, Liang Feng
Objective: Traumatic intracranial epidural hematoma is considered to be the serious complication of head injury requiring appropriate evaluation and surgical intervention. Although craniotomy provides an effective evacuation of the hematoma, there is an insufficient data to support one particular surgical treatment method. The objective of this study is to address the effectiveness of Urokinase instillation via single b

Jul 12, 2017Open    AccessArticle

The Cholinergic-Regulated Thalamocortical Imagining as Mind Differentiated in Two Phases of Sleep: A View from the Guangdong People

Zi-Jian Cai
Recently, many achievements on neural sciences have been made by the people in television, such as the adipose cause of male hypothalamic aging, and so on. In this article, it is reported that, on June 17 this year in evening in television, the people in Guangdong attending the Opening Ceremony of BRICS Games there suggested that the cholinergic-regulated thalamocortical activation would result in the cortical imagin

Jun 08, 2017Open    AccessArticle

A Combination of Tanacetum parthenium, Griffonia simplicifolia and Magnesium (Aurastop) as Symptomatic Acute Treatment for Migraine Aura: A Retrospective Cohort Study

Paola Zavarise, Giorgio Dalla Volta
Background: effective treatments for migraine aura and related symptoms are not yet well established. In the last years, several herbal and/or nutraceutical preparations have been proposed as potential treatment. We report the results of a retrospective analysis on the synergistic effect of three nutraceutical components (Tanacetum p

Apr 27, 2017Open    AccessArticle

JAK-STAT Lodges in Multiple Sclerosis: Pathophysiology and Therapeutic Approach Overview

Kabir Magaji Hamid, Abdullahi Isiyaku, Mustapha Umar Kalgo, Isah Suleiman Yahaya, Abbas Mirshafiey
Multiple sclerosis (MS) is a complex inflammatory and demyelinating disease of central nervous system (CNS). The disease pathogenesis is not fully understood and no actual cure for the disease yet. The disease has genetic and environmental cause as fundamental factors which are identified for the disease pathogenesis so far. One of the characteristic features of the disease is inflammation cause due to activation of pro-inflammato

Apr 19, 2017Open    AccessArticle

Neuron Specific Enolase, a Biomarker of Breast Cancer Cerebral Metastasis

Cristina Dumitrescu, Lieveke Ameye, Sofia Latifyan, Ziad Elali, Dominique Lossignol
Introduction: The diagnosis of brain metastasis and/or epilepsy remains a challenge in neurological symptomatic and asymptomatic cancer patients. Despite improved imagery and clinical approach, an early diagnosis requires more tools. Neuron Specific Enolase (NSE) is a specific molecular marker for mature nerve cells dosed at high levels in fetal and early postnatal brain, and is also a tumor marker in some types of neuroendocrine