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Mar 18, 2024Open Access
Coronary artery spasm (CAS) is the most common diagnosis in patient with non-obstructive coronary artery disease (INOCA). CAS has a great relation with the thyrotoxicosis. It leads to severe reversible coronary vasoconstriction with wide varieties of symptoms from just simple chest pain to sudden cardiac death. Many trials and investigations are still going on to reveal the pathophysiology and the mechanism. The symptoms may mimic acute coronary syndrome so the corner stone in the diagnosis is t...
Sep 07, 2023Open Access
The incidence of end-stage renal disease (ESRD) is increasing in the Philippines. The presence of diabetes mellitus further worsens ESRD prognosis. The neutrophil-to-lymphocyte ratio (NLR) is a reliable prognostic marker for mortality, but its usefulness as a prognostic biomarker in diabetes patients with chronic kidney disease is yet to be clarified. This study aimed to determine the association between NLR and morbidity among Filipino patients with end-stage renal disease (ESRD) secondary to d...
Apr 28, 2023Open Access
Hypothyroidism is a chronic disease resulting in a multiplicity of symptoms that can affect the physical and mental quality of life of patients. The aim of the present study was to assess the quality of life in these patients and to identify the factors associated with its deterioration. This is a cross-sectional study carried out in 2019-2020 at the Endocrinology Department at Chu Hassan II in Fez in Morocco. The assessment of the quality of life was based on the SF12 score, which allows to cal...
Apr 24, 2023Open Access
The aim of this study was to compare the quality of life (QoL) and the prevalence of depression and anxiety in patients with type 2 diabetes mellitus according to the type of treatment: insulin, oral therapy or both therapies. A cross-sectional study that included adults with diabetes mellitus type 2 was conducted at Hassan II University Hospital in Fez, Morocco. Patients are divided into 3 groups: the anti-diabetic agents’ group, the insulin therapy group and the combined therapy group. The Hos...
Jan 04, 2023Open Access
Introduction: Diabetic ketoacidosis is the most common acute complication of diabetic children. Objective: To determine the frequency of diabetic ketoacidosis in children, describe the evolutionary profile, and identify factors associated with death. Patients and Method: A retrospective, descriptive, analytical study was conducted between January 2018 and November 2019. Children aged 5 to 15 years with a discharge diagnosis of diabetic ketoacidosis were included. Variables studied were age, sex,...
Nov 21, 2022Open Access
Glucose-6-phosphate dehydrogenase (G6PD) is an enzyme in the pentose phosphate pathway (PPP) which reduces NADP to NADPH while oxidizing glucose-6-phosphate. NADPH subsequently acts as a reducing agent, allowing oxidized glutathione to be converted to reduced glutathione, which protects against oxidant damage. Objectives: This study aimed to assess G6PD activity in Sudanese diabetic patients and its relationship with hyperglycemia. Materials and Methods: This study was a case control study done ...
Oct 12, 2021Open Access
Objective: Diabetes is one of the most common pathologies in the world. Although its risk factors are known, it cannot be confirmed that all risk factors have a constant contribution to the development of type 2 diabetes from one population to another. In this regard, this retrospective study aims to assess the contribution of different risk factors in occurrence of type 2 diabetes in the Togolese population. Methods: In this retrospective study conducted between August and October 2020, we obta...
Sep 08, 2021Open Access
Background: Diabetes mellitus (DM) is a common chronic disease; it is associated with alterations of blood glucose and lipid profile. Current evidence indicated beneficial effects of some medicinal herbs on metabolic parameters. Aim: The aim of this study was to investigate the effect of Nigella Sativa (NS) supplementation on blood glucose and lipid profile levels among type 2 DM Sudanese patients. Materials and Methods: the experimental study was conducted at Gezira state-Khartoum during the pe...
May 26, 2021Open Access
Diabetes is a chronic metabolic disease that impairs the lifestyle of patients in different physical, mental and social dimensions. This study aims to investigate the determinants of health-related quality of life (HRQoL) in diabetics. A cross-sectional study was conducted on 526 diabetic patients followed in 2019 at the Hygiene Department of the Sidi Othmane district (Casablanca). The data were collected using a questionnaire gathering the demographic, clinical and paraclinical information of p...
Mar 17, 2021Open Access
The syndrome of familial isolated pituitary adenomas (FIPA) or predisposition to pituitary adenomas (PAP) is characterized by the presence within the same family of at least two isolated pituitary adenomas without any other type of associated endocrine tumor. These pituitary tumors may present as homogenous with the same tumor phenotype or heterogeneous with different patterns of pituitary tumor phenotypes (GH, Prolactine, ACTH secretion or non-functioning pituitary adenomas) within the same kin...
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