This article discusses a rare case of embryonal rhabdomyosarcoma (RMS) in a 32-year-old adult with a history of chronic smoking. The patient presented symptoms of dysuria and frequent urination, leading to the discovery of a low-grade RMS in the bladder. After surgery, the patient underwent adjuvant chemotherapy following a specific treatment plan. The article highlights the rarity of bladder RMS in adults, its diagnosis, and the recommended adjuvant chemotherapy as a treatment approach for localized cases.
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Hajar, M. , Imane, O. , Jihane, C. , Oumaima, S. , Samia, M. , Lamiae, A. , Karima, O. , Zineb, B. , Samia, A. and Nawfel, M. (2024). Embryonal Rhabdomyosarcoma of the Bladder in Adults: A Case Report and Comprehensive Literature Review. Open Access Library Journal, 11, e1153. doi: http://dx.doi.org/10.4236/oalib.1111153.
Ognjanovic, S., Linabery, A.M., Charbonneau, B. and Ross, J.A. (2009) Trends in Childhood Rhabdomyosarcoma Incidence and Survival in the United States, 1975-2005. Cancer, 115, 4218-4226. https://doi.org/10.1002/cncr.24465
Ahsaini, M., Ouattar, K., Azelmad, H., Mellas, S., Ammari, J.E., Tazi, M.F., et al. (2018) A Rare Pure Embryonal Rhabdomyosarcoma of the Urinary Bladder in an Adult Successfully Managed with Neoadjuvant Chemotherapy and Surgery: A Case Report. Journal of Medical Case Reports, 12, 329.
https://doi.org/10.1186/s13256-018-1870-1
Dahm, P. and Gschwend, J.E. (2003) Malignant Non Urothelial Neoplasms of the Urinary Bladder: A Review. European Urology, 44, 672-681.
https://doi.org/10.1016/S0302-2838(03)00416-0
Tembely, A., Kassogue, A., Diakite, M.L., Berthe, H.J.G., Coulibaly, B., Samassekou, A., et al. (2017) Rhabdomyosarcome vésical chez l’enfant de 12 mois: Un cas rarissime. Médecine d’Afrique Noire, 64, 594-598.
Vujanic, G.M. and Sandstedt, B. (2010) The Pathology of Wilms’ Tumour (Nephroblastoma): The International Society of Paediatric Oncology Approach. Journal of Clinical Pathology, 63, 102-109. https://doi.org/10.1136/jcp.2009.064600
Mackenzie, A.R., Whitmore, Jr.W.F. and Melamed, M.R. (1968) Myosarcomas of the Bladder and Prostate. Cancer, 22, 833-844.
https://doi.org/10.1002/1097-0142(196810)22:4<833::AID-CNCR2820220422>3.0.CO;2-I
Parekh, D.J., Jung, C., O’Conner, J., Dutta, S. and Smith, Jr.E.R. (2002) Leiomyosarcoma in Urinary Bladder after Cyclophosphamide Therapy for Retinoblastoma and Review of Bladder Sarcomas. Urology, 60, 164.
https://doi.org/10.1016/S0090-4295(02)01701-6
Rodeberg, D.A., Anderson, J.R., Arndt, C.A., Ferrer, F.A., Raney, R.B., Jenney, M.E. et al. (2011) Comparison of Outcomes Based on Treatment Algorithms for Rhabdomyosarcoma of the Bladder/Prostate: Combined Results from the Children’s Oncology Group, German Cooperative Soft Tissue Sarcoma Study, Italian Cooperative Group, and International Society of Pediatric Oncology Malignant Mesenchymal Tumors Committee. International Journal of Cancer 128, 1232-1239.
https://doi.org/10.1002/ijc.25444
