Antibiotherapy during Bacterial Infection in Chronic Kidney Disease Patient Hospitalized in Nephrology of National Hospital Donka

The research on infectious pathologies and antibiotic treatments has undergone rapid development, marked by the emergence of new pathogens and by the evolution of resistance to antibiotics despite the marketing of new agent. The aim of this study was to evaluate the use of antibiotics in bacterial infection in our context. The aim of this study was to evaluate the use of antibiotics in bacterial infection in our context. We conducted a descriptive study lasting 6 months from January 2 to June 30, 2019. We included all hospitalized patient who presented signs of infection, subjected to antibiotic therapy. We research the frequency, the socio-demographic parameter, clinical and biological parameters. During the study period, we had 162 hospitalized patients, only 66 (41%) presented with an infectious syndrome. The mean age was 45 ± 3.5 years. There was a predominance of men 35 (53.03%). According to clinical parameters, the mean temperature was 38.28 ( /- 1.022)°C, chills, sweat, dyspnea and meningeal syndrome. The mean duration of antibiotic therapy was 14 ± 7 days with extremes [3 to 21 days]. The biology was characterized by polynuclear neutrophilic leukocytosis in 37 (75.51%), an inflammatory syndrome with an elevated CRP in 37 patients with a mean of 24 ± 12 mg/L. Antibiotic are regularly prescribed for bacterial infections in chronic renal failure. Bacterial resistance represents a very high risk factor for mortality in CKD patient because of the associated co-morbidities.