Introduction: Glaucoma is the leading cause of irreversible blindness worldwide. It impairs the patient’s quality of life. This study aims to measure the quality of life in Moroccan patients with glaucoma and determine associated factors. Methods: A cross-sectional study was carried out in the ophthalmology consultation of the Omar Drissi Hospital of the Hassan II University Hospital of Fez between November 2021 and February 2022, including patients followed for glaucoma. The “15-item Glaucoma Quality of Life (GQL-15)” questionnaire was used to measure the quality of life. Multiple linear regression analyses were performed to identify factors associated with Glaucoma Related Quality of Life (GRQoL). Results: A total of 170 patients were included. Primary open-angle glaucoma was found in 72.9% of patients. Sixty percent were women, and 60.6% were 60 years of age and older. The mean total score of GQL-15 was 38.59 ± 16.71. The multiple linear regression model showed a significant association between high GRQoL and early age (β = -5.81, 95% CI: -10.46 - -1.16), high study level (β = -17.05, 95% CI: -27.50 - -6.60), glaucoma early screening (β = -9.75, 95% CI: -16.64 - -2.87), glaucoma moderate stage (β = -8.08, 95% CI: -13.82 - -2.35) and with only one eye-drop per day (β = -6.69, 95% CI: -11.73 - -1.64). Conclusion: Glaucoma-related quality of life was reduced and multifactorial. These findings could serve as a basis for future research into disease burden, including an examination of disease costs.
Cite this paper
Maiouak, M. , Taybi, H. E. O. , Chakri, I. , Omari, M. , Berraho, M. , Abdellaoui, M. , Tachfouti, N. , Andaloussi, I. B. and Fakir, S. E. (2023). Assessment of Quality of Life among Moroccan Patients with Glaucoma. Open Access Library Journal, 10, e016. doi: http://dx.doi.org/10.4236/oalib.1110016.
Quigley, H.A. and Broman, A.T. (2006) The Number of People with Glaucoma Worldwide in 2010 and 2020. British Journal of Ophthalmology, 90, 262-267.
https://doi.org/10.1136/bjo.2005.081224
Cook, C. and Foster, P. (2012) Epidemiology of Glaucoma: What’s New? Canadian Journal of Ophthalmology, 47, 223-226. https://doi.org/10.1016/j.jcjo.2012.02.003
Gupta, N. and Yücel, Y.H. (2007) Glaucoma as a Neurodegenerative Disease. Current Opinion in Ophthalmology, 18, 110-114.
https://doi.org/10.1097/ICU.0b013e3280895aea
Tham, Y.-C., Li, X., Wong, T.Y., et al. (2014) Global Prevalence of Glaucoma and Projections of glaucoma Burden through 2040: A Systematic Review and Meta-Analysis. Ophthalmology, 121, 2081-2090.
https://doi.org/10.1016/j.ophtha.2014.05.013
Chakib, A., Ouarrach, N., Haloui, M., Elbelhadji, M. and Amraoui, A. (2010) Viscocanalostomy: Preliminary Clinical Results. Journal Français d’Ophtalmologie, 33, 403-407. https://doi.org/10.1016/j.jfo.2010.03.009
Jampel, H.D., Frick, K.D., Janz, N.K., et al. (2007) Depression and Mood Indicators in Newly Diagnosed Glaucoma Patients. American Journal of Ophthalmology, 144, 238-244.e1. https://doi.org/10.1016/j.ajo.2007.04.048
Janz, N.K., Wren, P.A., Guire, K.E., et al. (2007) Fear of Blindness in the Collaborative Initial Glaucoma Treatment Study: Patterns and Correlates over Time. Ophthalmology, 114, 2213-2220. https://doi.org/10.1016/j.ophtha.2007.02.014
Nelson, P., et al. (2003) Quality of Life in Glaucoma and Its Relationship with Visual Function. Journal of Glaucoma, 12, 139-150.
https://journals.lww.com/glaucomajournal/Abstract/2003/04000/Quality_of_Life_in_Glaucoma_and_Its_Relationship.9.aspx
Jampel, H.D., Schwartz, A., Pollack, I., et al. (2002) Glaucoma Patients’ Assessment of Their Visual Function and Quality of Life. Journal of Glaucoma, 11, 154-163.
https://doi.org/10.1097/00061198-200204000-00012
Margolis, M.K., Coyne, K., Kennedy-Martin, T., et al. (2002) Vision-Specific Instruments for the Assessment of Health-Related Quality of Life and Visual Functioning: A Literature Review. PharmacoEconomics, 20, 791-812.
https://doi.org/10.2165/00019053-200220120-00001
Nelson, P., Aspinall, P., Papasouliotis, O., Worton, B. and O’Brien, C. (2003) Quality of Life in Glaucoma and Its Relationship with Visual Function. Journal of Glaucoma, 12, 139-150. https://doi.org/10.1097/00061198-200304000-00009
Chylack, L.T., Leske, M.C., McCarthy, D., et al. (1989) Lens Opacities Classification System II (LOCS II). Archives of Ophthalmology, 107, 991-997.
https://doi.org/10.1001/archopht.1989.01070020053028
Nelson, P., Aspinall, P., Papasouliotis, O., Worton, B. and O’Brien, C. (2003) Quality of Life in Glaucoma and Its Relationship with Visual Function. Journal of Glaucoma, 12, 139-150. https://doi.org/10.1097/00061198-200304000-00009
Bhandary, S.V., Kusumkar, P., Rao, L.G., Abbagani, S. and Addoor, K.R. (2020) Assessment of Quality of Life in Glaucoma Patients Using the Glaucoma Quality of Life-15 Questionnaire. Asian Journal of Ophthalmology, 17, 273-284.
https://doi.org/10.35119/asjoo.v17i3.617
Goldberg, I., Clement, C.I., Chiang, T.H., et al. (2009) Assessing Quality of Life in Patients With Glaucoma Using the Glaucoma Quality of Life-15 (GQL-15) Questionnaire. Journal of Glaucoma, 18, 6-12. https://doi.org/10.1097/IJG.0b013e3181752c83
Zhou, C., Qian, S., Wu, P. and Qiu, C. (2014) Quality of Life of Glaucoma Patients in China: Sociodemographic, Clinical, and Psychological Correlates—A Cross-Sectional Study. Quality of Life Research, 23, 999-1008.
https://doi.org/10.1007/s11136-013-0518-2
Wang, Y., Zhao, Y., Xie, S., et al. (2019) Resilience Mediates the Relationship between Social Support and Quality of Life in Patients with Primary Glaucoma. Frontiers in Psychiatry, 10, Article 22. https://doi.org/10.3389/fpsyt.2019.00022
Onakoya, A.O., Mbadugha, C.A., Aribaba, O.T. and Ibidapo, O.O. (2012) Quality of Life of Primary Open Angle Glaucoma Patients in Lagos, Nigeria: Clinical and Sociodemographic Correlates. Journal of Glaucoma, 21, 287-295.
https://doi.org/10.1097/IJG.0b013e31820d7cfd
Omoti, A.E., Waziri-Erameh, M.J. and Osahon, A.I. (2002) The Relationship between Socio-Demographic Factors and Severity of Visual Field Loss in Glaucoma Patients at Initial Presentation In Benin-City, Nigeria. Sahel Medical Journal, 5, 195-198. https://doi.org/10.4314/smj2.v5i4.12828
Moyer, V.A. (2013) Screening for Glaucoma: U.S. Preventive Services Task Force Recommendation Statement. Annals of Internal Medicine, 159, 484-489.
https://doi.org/10.7326/0003-4819-159-6-201309170-00685
Skalicky, S. and Goldberg, I. (2008) Depression and Quality of Life in Patients with Glaucoma: A Cross-Sectional Analysis Using the Geriatric Depression Scale-15, Assessment of Function Related to Vision, and the Glaucoma Quality of Life-15. Journal of Glaucoma, 17, 546-551. https://doi.org/10.1097/IJG.0b013e318163bdd1
van Gestel, A., Webers, C.B., Beckers, H.J.M., et al. (2010) The Relationship between Visual Field Loss in Glaucoma and Health-Related Quality-of-Life. Eye (London), 24, 1759-1769. https://doi.org/10.1038/eye.2010.133
Hirneiss, C., Vogel, M., Kampik, A., Neubauer, A.S. and Kernt, M. (2011) Measurement of Glaucoma-Specific Functionality with the GQL-15 and Correlation with Parameters of Visual Function. Ophthalmologe, 108, 939-946.
https://doi.org/10.1007/s00347-011-2402-1
Wang, B., Aung, T., Marella, M., et al. (2013) Impact of Bilateral Open and Closed-Angle Glaucoma on Glaucoma-Specific Functioning in Asians. Journal of Glaucoma, 22, 330-335. https://doi.org/10.1097/IJG.0b013e3182408593
Nordmann, J.-P., Auzanneau, N., Ricard, S. and Berdeaux, G. (2003) Vision Related Quality of Life and Topical Glaucoma Treatment Side Effects. Health and Quality of Life Outcomes, 1, Article No. 75. https://doi.org/10.1186/1477-7525-1-75
Austin, P.C. and Steyerberg, E.W. (2015) The Number of Subjects per Variable Required in Linear Regression Analyses. Journal of Clinical Epidemiology, 68, 627-636.
https://doi.org/10.1016/j.jclinepi.2014.12.014