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Identification of Sec-Butylamine and Methenamine and Other Bioactive Compounds from Edible Azadirachta indica Methanolic Extracts Using GC-MS

DOI: 10.4236/oalib.1109750, PP. 1-17

Subject Areas: Medicinal Chemistry

Keywords: Azadirachta indica, Neem, GC-MS, Bioactive, Sec-Butylamine, Methenamine

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Abstract

Background: Azadirachta indica (Neem) is a medicinal plant that is traditionally known for its antimicrobial properties. The present study was aimed to determine the bioactive components of the A. indica leaves using GC-MS. Results: Results revealed presence of 35 different active compounds in different percentage composition successions. Bioactive compounds listed include; Methenamine, Hexadecanoic acid, methyl ester; Phenol; Dodecanoic acid, methyl ester; Methyl tetradecanoate; sec-Butylamine; 2-Propanone, 1-methoxy-; 10-Octadecenoic acid, methyl ester; Heptadecanoic acid, 16-methyl-; Phenol, 2,6-dimethoxy-; Phenol, 2-methoxy-; n-Hexadecanoic acid. Their molecular weight and formula was observed while their biological activities were also illustrated. Conclusions: The findings of this study suggest that A. indica leaf collected from the study area contain sec-Butylamine and Methenamine that have not been identified from other studies which are important bioactive compounds that can be used in several biological activities.

Cite this paper

Ihenetu, F. C. , Okorondu, S. I. , Chikwendu, C. I. , Nwabueze, R. N. and Anekwe, I. I. (2024). Identification of Sec-Butylamine and Methenamine and Other Bioactive Compounds from Edible Azadirachta indica Methanolic Extracts Using GC-MS. Open Access Library Journal, 11, e9750. doi: http://dx.doi.org/10.4236/oalib.1109750.

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