Diabetes is a chronic metabolic disease that impairs the lifestyle of patients in different physical, mental and social dimensions. This study aims to investigate the determinants of health-related quality of life (HRQoL) in diabetics. A cross-sectional study was conducted on 526 diabetic patients followed in 2019 at the Hygiene Department of the Sidi Othmane district (Casablanca). The data were collected using a questionnaire gathering the demographic, clinical and paraclinical information of patients, as well as a description of health status in the 5 dimensions by the EQ-5D questionnaire. The data was analyzed using SPSS version 23 software. The determinants of quality of life were assessed using the ANOVA test and the Pearson correlation test. The result is considered statistically significant at 0.05. The average quality of life score based on the EQ-5D-3L scale and the VAS analog visual scale was 0.52 ± 0.34 and 55.47 ± 15.50, respectively. Severe problems were observed in anxiety/depression dimensions in 19.20% of patients, while the highest percentages for moderate problems were for the pain/physical discomfort and mobility dimensions (53.80% and 36.90% respectively). The average scores of the EQ-5D-3L and visual analogue scale (VAS) were significantly (P < 0.05) associated with age, gender, education, marital status, professional activity and complications. It follows from this study that the HRQoL of the population of diabetics studied is influenced by many factors, which must be considered in order to achieve better management of diabetes and improve their quality of life.
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