Background: The literature
suggests that the haemostatic abnormalities have taken a big part in
preeclampsia. D-dimer is a biomarker of fibrin formation and degradation. Objective: The present study was
aimed to estimate and evaluation of
the plasma D-dimer levels in Sudanese preeclampsia women. Material and Methods: This is an analytical
descriptive case control study done
during March 2016. A total of 100 participants were enrolled in this study, classified into two groups: the first group
consisted of 50 Sudanese women diagnosed by preeclampsia as patients
group, while the second group consisted of 50
normotensive women and their age matched to patients, designated as normal control
group. 3 milliter of veins blood samples were collected in containers containing
3.2% tri sodium citrate as anticoagulant, then the platelet-poor plasma was prepared
immediately by centrifuging for 15 minutes
at approx 3000 rpm. The plasma D-dimer levels were done using MISPA-i2 (Switzerland).
The data were analyzed by using SPSS (version 20). Results: The current study
showed that the D-dimer level was statistically significant higher in
preeclampsia women compared with normotensive pregnant women (Mean ± SD: 1.016 ±
0.158 vs 0.168 ± 0.045 with P value 0.000, respectively). Conclusion: This
study concluded that the plasma D-dimer level was significantly elevated in
Sudanese women with preeclampsia.
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