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The Differences of Characteristic, Management, Maternal and Perinatal Outcomes among Early and Late Onset Preeclampsia

DOI: 10.4236/oalib.1102750, PP. 1-7

Subject Areas: Gynecology & Obstetrics

Keywords: Early Onset Preeclampsia and Late Onset Preeclampsia, Management, Maternal and Perinatal Outcomes

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Abstract

Objectives: Preeclampsia (PE) is still a problem in the field of obstetrics. This is due to the unclear etiology, morbidity and mortality are still high. Currently, there has been a change in the definition and understanding of Preeclampsiaa, Early Onset Preeclampsiaa (EOPE) and Late Onset Preeclampsiaa (LOPE). EOPE is a disorder accompanied by severe complications for both the mother and the perinatal due to placental factors, while LOPE is a disorder that is characterized by a mild complications in maternal from maternal disorders. This study aims to find differences in characteristics, management, maternal and perinatal outcomes to EOPE and LOPE. Methods: An analytic observational study was done with cross sectional design involving retrospective data 433 pregnant women with preeclampsia who delivered in Hasan Sadikin Hospital Bandung. Data were taken from January 2013 to December 2014. It was noted the characteristics, management, maternal and perinatal outcomes. Data were analyzed using parametric and nonparametric test with significance p < 0.05. Results: The results showed that the incidence of EOPE (27.5%) was lower than LOPE (72.5%). Diastolic blood pressure is significantly higher in EOPE 109.71 ± 10.761 and 106.05 ± 8.871 compared to LOPE. The most spontaneous delivery is with EOPE labor (91.2%) while in LOPE delivery with using forceps (73.8%). Long of stay in EOPE at 5.59 ± 6.90 is longer than the LOPE at 5.32 ± 4.70. Complications in perinatal outcomes such as low birth weight (<2500 gram) are more in EOPE (97.5%) compared to LOPE (45.6%) and asphyxia is more on EOPE (11.7%) compared to LOPE (1.3%). Stillbirth in EOPE (16%) is more than LOPE group (2.8%). Conclusions: It is obtained that EOPE incidence rate is lower than LOPE. Mother and perinatal complications are greater in the EOPE group.

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Aziz, A. and Mose, J. C. (2016). The Differences of Characteristic, Management, Maternal and Perinatal Outcomes among Early and Late Onset Preeclampsia. Open Access Library Journal, 3, e2750. doi: http://dx.doi.org/10.4236/oalib.1102750.

References

[1]  Lisonkova Joseph, K.S. (2013) Incidence of Preeclampsia: Risk Factors and Outcomes Associated with Early- versus Late-Onset Disease. American Journal of Obstetrics & Gynecology, 209, 544.e1-544 e12.
[2]  Hutcheon, J.A., Lisonkova, S. and Joseph, K.S. (2011) The Epidemiology of Preeclampsia and the Hyper-Tensive Disorders of Pregnancy. Best Practice & Research Clinical Obstetrics & Gynaecology, 25, 391-403.
http://dx.doi.org/10.1016/j.bpobgyn.2011.01.006
[3]  Sibai, B., Dekker, G. and Kupferminc, M. (2005) Pre-Eclampsia. Lancet, 365, 785-799.
http://dx.doi.org/10.1016/S0140-6736(05)71003-5
[4]  Khan, K.S., Wojdyla, D., Say, L., Gulmezoglu, A.M. and Van Look, P.F. (2006) WHO Analysis of Causes of Maternal Death: A Systematic Review. Lancet, 367, 1066-1074.
http://dx.doi.org/10.1016/S0140-6736(06)68397-9
[5]  Steegers, E.A.P., Von Dadelszen, P., Duvekol, J.J. and Pijnenborg, R. (2010) Preeclampsia. Lancet, 376, 631-644.
http://dx.doi.org/10.1016/S0140-6736(10)60279-6
[6]  Kuklina, E.V., Ayala, C. and Callaghan, W.M. (2009) Hyper-Tensive Disorders and Severe Obstetric Morbidity in the United States. Obstetrics & Gynecology, 113, 1299-1306.
http://dx.doi.org/10.1097/AOG.0b013e3181a45b25
[7]  Knight, M. (2007) Eclampsia in the United Kingdom, 2005. BJOG, 114, 1072-1078.
http://dx.doi.org/10.1111/j.1471-0528.2007.01423.x
[8]  MacKay, A.P., Berg, C.J. and Atrash, H.K. (2001) Pregnancy-Related Mortality from Pre-Eclampsia and Eclampsia. Obstetrics & Gynecology, 97, 533-538.
[9]  Tranquilli, A.L., Brown, M.A., Zeeman, G.G., Dekker, G., Sibai, B.M., The Definition of Severe and Early-Onset Pre- eclampsia (2013) Statements from the International Society for the Study of Hypertension in Pregnancy (ISSHP). Pre- gnancy Hypertension, 3, 44-47.
http://dx.doi.org/10.1016/j.preghy.2012.11.001
[10]  Tranquilli, A.L., Dekker, G., Magee, L., et al. (2014) The Classification, Diagnosis and Management of the Hyper- tensive Disorders of Pregnancy: A Revised Statement from the ISSHP. Pregnancy Hypertension, 4, 97-104.
http://dx.doi.org/10.1016/j.preghy.2014.02.001
[11]  Publications Committee Sfm-FM, Sibai, B.M. (2011) Evaluation and Management of Severe Preeclampsia before 34 Weeks’ Gestation. American Journal of Obstetrics & Gynecology, 205, 191-198.
http://dx.doi.org/10.1016/j.ajog.2011.07.017
[12]  Hall, D.R., Odendaal, H.J., Steyn, D.W. and Grove, D. (2000) Expectant Management of Early Onset, Severe Pre- eclampsia: Maternal Outcome. BJOG, 107, 1252-1257.
http://dx.doi.org/10.1111/j.1471-0528.2000.tb11616.x
[13]  Raymond, D. and Peterson, E. (2011) A Critical Review of Early-Onset and Late-Onset Preeclampsia. Obstetrical & Gynecological Survey, 66, 497-506.
[14]  Roberts, J.M. and Hubel, C.A. (2009) The Two Stage Model of Pre-Eclampsia: Variations on the Theme. Placenta, 30, S32-S37.
http://dx.doi.org/10.1016/j.placenta.2008.11.009
[15]  Ness, R.B. and Roberts, J.M. (1996) Heterogeneous Causes Constituting the Single Sydrome of Pre-Eclampsia: A Hypothesis and Its Implication. American Journal of Obstetrics & Gynecology, 175, 1365-1370.
http://dx.doi.org/10.1016/S0002-9378(96)70056-X
[16]  Von Dadelszen, P., Magee, L.A. and Roberts, J.M. (2003) Subclassification of Pre-Eclampsia. Hypertension in Pre- gnancy, 22, 143-148.
http://dx.doi.org/10.1081/PRG-120021060
[17]  Evidence CfEa (2012) New South Wales Maternal and Babies Report 2010, [10347674].
[18]  Lowe, S.A., Brown, M.A., Dekker, G.A., et al. (2009) Guidelines for the Management of Hypertensive Disorders of Pregnancy 2008. Australian and New Zealand Journal of Obstetrics and Gynaecology, 49, 242-246.
http://dx.doi.org/10.1111/j.1479-828X.2009.01003.x
[19]  Churchill, D., Duley, I., Thornton, J.G. and Jones, I. (2013) Interventionist versus Expectant Care for Severe Pre- Eclampsia between 24 and 34 Weeks’ Gestation. Cochrane Database of Systematic Reviews, No. 7, Article ID: CD0033106.
http://dx.doi.org/10.1002/14651858.cd003106.pub2
[20]  Sibai, B.M. (2011) Management of Late Pretern and Early-Term Pregnancies Complicated by Mild Gestational Hypertension/Pre-Eclampsia. Seminars in Perinatology, 35, 292-296.
http://dx.doi.org/10.1053/j.semperi.2011.05.010
[21]  Resnick, M.B., Armstrong, S. and Carter, R.I. (1988) Developemental Intervention Program for High-Risk Premature Infants Interactions. Journal of Developmental & Behavioral Pediatrics, 9, 73-78.
Steegers, E.A.P., Von Dadelszen, P., Duvekot, J.J. and Pijnenborg, R. (2010) Pre-Eclampsia. The Lancet, 376, 631-644.
http://dx.doi.org/10.1016/S0140-6736(10)60279-6
[22]  Pettit, F., Mangos, G., Davis, G., Henry, A. and Brown, M.A. (2015) Preeclampsia Causes Adverse Maternal Out- comes across the Gestational Spectrum. Pregnancy Hypertension: An International Journal of Womens Cardiovas- cular Health, 5, 198-204.
[23]  Paruk, F. and Moodley, J. (2000) Maternal and Neonatal Outcome in Early- and Late-Onset Pre-Eclampsia. Seminars in Neonatology, 5, 197-207.
http://dx.doi.org/10.1053/siny.2000.0023
[24]  Hall, D.R., Odendaal, H.J., Kirsten, G.F., Smith, J. and Grove, D. (2000) Expectant Management of Early Onset, Severe Pre-Eclampsia: Perinatal Outcome. BJOG: An International Journal of Obstetrics & Gynaecology, 107, 1258- 1264.
http://dx.doi.org/10.1111/j.1471-0528.2000.tb11617.x
[25]  Sibai, B.M. (2013) What to Expectant Management in Severe Preeclampsia at <34 Weeks Gestation: Pregnancy Outcomes in Developed vs Developing Countries. American Journal of Obstetrics and Gynecology, 209, 400-401.
http://dx.doi.org/10.1016/j.ajog.2013.08.024

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