Objective: This single-blind, randomized study aimed to evaluate effects
of acupuncture stimulation at the GV 20 point on the electroencephalogram
(EEG). Methods: Data was collected from 17 volunteers, aged 18 - 25 years old.
EEG recordings were obtained before and after verum acupuncture and after a one-week
interval EEG recording was also obtained before and after sham acupuncture.
Spectral analysis of the EEG data was compared to baseline EEG. Results:
Compared to baseline, there was an increase in the alpha band power at the T4
and T5 electrodes (p < 0.05) and a decrease in the beta band power at
the T4, T6, and A2 electrodes following verum acupuncture. However, comparison
of the data recorded before and after sham acupuncture revealed no significant
differences. Conclusions: We claim that verum acupuncture stimulation at the GV
20 point has an effect on brain activity, which might be due to the known “mood
modifying, relaxation effect” at that point.
Cite this paper
Cabioglu, M. T. , Toprak, M. K. , Yilmaz, D. and Cabioglu, C. (2016). Effect of Acupuncture Stimulation of GV 20 Point on Electroencephalogram. Open Access Library Journal, 3, e2653. doi: http://dx.doi.org/10.4236/oalib.1102653.
Moffet, H.H. (2006) How Might Acupuncture Work? A Systematic
Review of Physiologic Rationales from Clinical Trials. BMC
Complementary and Alternative Medicine,6, 25. http://dx.doi.org/10.1186/1472-6882-6-25
Napadow, V., Ahn, A., Longhurst, J., et al.
(2008) The Status and Future of Acupuncture Mechanism Research. he Journal of Alternative and Complementary Medicined, 14, 861-869. http://dx.doi.org/10.1089/acm.2008.SAR-3
MacPherson, H., Altman, G.D., Hammerschlag, R., et al. (2010) Revised Standards for
Reporting Interventions in Clinical Trials of Acupuncture (STRICTA): Extending
the CONSORT Statement. PLoS Medicine, 7, e1000261. http://dx.doi.org/10.1371/journal.pmed.1000261
Chen, A.C., Liu, F.J.,
Wang, L. and Arendt-Nielsen, L. (2006) Mode and Site of Acupuncture Modulation in
the Human Brain: 3D (124-ch) EEG Power Spectrum Mapping and Source Imaging. Neuroimage, 29, 1080-1091. http://dx.doi.org/10.1016/j.neuroimage.2005.08.066
Litscher, G. (2010) Ten Years Evidence-based High-Tech
Acupuncture Part 3: A Short Review of Animal Experiments. Evidence-Based Complementary and Alternative Medicine, 7, 151-155. http://dx.doi.org/10.1093/ecam/nen034
Streitberger, K., Steppan, J., Maier, C., et al.
(2008) Effects of Verum Acupuncture Compared to Placebo Acupuncture on Quantitative
EEG and Heart Rate Variability in Healthy Volunteers. The
Journal of Alternative and Complementary Medicine, 14,
Sakai, S., Hori, E., Umeno, K., et al.
(2007) Specific Acupuncture Sensation Correlates with EEGs and Autonomic
Changes in Human Subjects. Autonomic
Neuroscience: Basic and Clinical, 133, 158-169. http://dx.doi.org/10.1016/j.autneu.2007.01.001
Tong, J.J., Zhu, D.H., Chen, Y.Q., Lv, Y.Y. and Chen, H.D. (2008) Effects of Acupuncture in Pain Relief Based
on EEG Research. International Conference
on Information Technology and Applications in Biomedicine, Shenzhen, 30-31 May 2008, 578-581. http://dx.doi.org/10.1109/ITAB.2008.4570521
Rosted, P., Griffiths, P.A., Bacon, P. and Gravill, N. (2001) Is There an Effect of Acupuncture
on the Resting EEG? Complementary
Therapies in Medicine, 9, 77-81. http://dx.doi.org/10.1054/ctim.2001.0435
Xu, M., Tomotake, M., Ikuta, T., Ishimoto, Y. and Okura, M. (1998) The Effects of Qi-Gong and
Acupuncture on Human Cerebral Evoked Potentials and Electroencephalogram. The Journal of Medical Investigation, 44,
Zhang, G.F., Qu, S.S., Zheng, Y., Chen, J.Q., Deng, G.Z., Yang, C.H. and Huang, Y. (2013) Key Regions of
the Cerebral Network Are Altered after Electroacupuncture at the Baihui (GV 20) and Yintang Acupuncture Points in Healthy Volunteers: An Analysis Based on Resting fcMRI. Acupuncture in Medicine, 31, 383-388. http://dx.doi.org/10.1136/acupmed-2012-010301
Chang, S. (2013) The Meridian System and Mechanism of Acupuncture:
A Comparative Review. Part 3: Mechanisms of Acupuncture Therapies. Taiwanese Journal of Obstetrics and
Gynecology Home, 52, 171-184. http://dx.doi.org/10.1016/j.tjog.2013.04.005
Li, L., Liu, H., Li, Y.-Z., et al. (2008) The Human Brain Response to Acupuncture on Same-Meridian Acupoints: Evidence
from an fMRI Study. Journal of
Alternative and Complementary Medicine, 14, 673-678. http://dx.doi.org/10.1089/acm.2008.0036
Zhang, W., Luo, F., Qi, Y., Wang, Y., Chang, J., Woodward, D.J., Chen, A.C. and Han, J. (2003) Modulation of Pain Signal
Processing by Electric Acupoint Stimulation: An Electroencephalogram Study. Acta Scientiarum Naturalium Universitatis Pekinensis, 35, 236-240.
Abad-Alegria, F., Pomaròn, C., Aznar, C., Munoz, C. and Adelantado,
S. (2001) Objective
Assessment of the Sympatholytic Action of the Nei-Kuan Acupoint. The American Journal of Chinese Medicine,
29, 201-210. http://dx.doi.org/10.1142/S0192415X0100023X