全部 标题 作者
关键词 摘要


Phytochemical Investigation of Antimicrobial and Antioxidant Activity Leaves Extracts of Corchorus olitorius

DOI: 10.4236/oalib.1102225, PP. 1-5

Subject Areas: Pharmacology

Keywords: Phytochemical Screening, Extract, Corchorus olitorius Leaves, Antimicrobial Activity, Minerals Content

Full-Text   Cite this paper   Add to My Lib

Abstract

The leaves extracts of Corchorus olitorius, the family Malvaceae, are commonly called khudra, the plant extensively used in Sudanese traditional medicine. The Sudanese varieties are one of the best in the market, which prompted investigation of leaves extracts. Some chemical analyses of the leaves have been done such as determination of ash content and trace elements (Ca, Fe, Mg, and Na) by atomic absorption spectrometry. The 96% ethanolic, Ethyl acetate and chloroform extracts exhibited significant antimicrobial activity and highlighted the biological monitoring of activity in order to isolate the active metabolites from the ethanolic extract of the leaves. The presence of sterols and triterpenes, carotenoids, coumarins, alkaloids, saponins, tannins, flavonoid and carbohydrates was confirmed by phytochemical screening of the diethyl ether, methanolic and aqueous extracts of the leaves. The extracts were screened in different solvent systems by thin layer chromatography. The methanolic, Ethyl acetate extract exhibited significant antioxidant activity. From the above-mentioned extract we prepare cream and ointment as antibacterial and antifungal dosage forms.

Cite this paper

Mohammed, R. M. O. (2016). Phytochemical Investigation of Antimicrobial and Antioxidant Activity Leaves Extracts of Corchorus olitorius. Open Access Library Journal, 3, e2225. doi: http://dx.doi.org/10.4236/oalib.1102225.

References

[1]  Elghazali, G.E., Elsadig, W., Elsubki, H. and Kalafalla, M. (2003) Medicina Plants of the Sudan. Part V. Medicinal Plants of Ingassana Area. National Centre for Researches, Medicinal and Aromatic Plants, Researches Institute, Khartoum.
[2]  Sofowora, A. (1993) Phytochemical Screening of Medicinal Plants and Traditional Medicine in Africa Edition. Spectrum Books Ltd., Nigeria, 150-156.
[3]  Kavangh, F. (1972) Analytical Microbiology. In: Kavangh, Ed., Academic Press, New York and London, 1-11.
[4]  Atlas, R.M. (1989) Basic and Practical Microbiology. Macmillan Publishing Company, USA.
[5]  Stock, R. and Rice, C.B.F. (1967) Rice of Chromatographic Methods. 3rd Edition, Science Paper Backs, London.
[6]  Shimada, K., Fujikawa, K., Yahara, K. and Nakamura, T. (1920) Antioxidative Properties of Xanthan on the Antioxidation of Soybean Oil in Cyclodextrin Emulsion. Journal of Agricultural and Food Chemistry, 40, 409-458.
[7]  Dinis, T.C.P., Madeira, V.M.C. and Almeida, L.M. (1994) Action of Phenolic Derivates (Acetoaminophen, Salycilate, and 5-Aminosalycilate) as Inhibitors of Membrane Lipid Peroxidation and as Peroxyl Radical Scavengers. Archives of Biochemistry and Biophysics, 315, 161-169.
http://dx.doi.org/10.1006/abbi.1994.1485
[8]  Ansel, H.C., Allen Jr., L.V. and Popovich, N.G. (2009) Pharmaceutical Dosage from and Drug Delivery Systems. 9th Edition.
[9]  AOAC (1989) Official Methods of Analysis of the Association of Official Analytical Chemistry. 4th Edition, Washington DC.

Full-Text


comments powered by Disqus