Generalized spinal cord atrophy is rare. Several causes can be found
responsible for this entity. Marfan syndrome
(MS) is a clinically and allelically heterogeneous, heritable connective tissue
disorder. Previous study has implicated neuromuscular involvement in this
syndrome. Here, we report the description of a patient with generalized spinal
cord atrophy, which may be attributed to MS. Though not all patients represent with
spinal cord atrophy, our case suggests that generalized spinal cord atrophy may
occur in a subgroup of MS patients. Our finding underscores the need to inform
medical practitioners that neurologic involvement, especially generalized
spinal cord atrophy, can occur in patients with MS. Further studies are warranted
in order to better clarify this causal relationship association between MS and spinal
cord atrophy.
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