全部 标题 作者
关键词 摘要

OALib Journal期刊
ISSN: 2333-9721
费用:99美元

查看量下载量

相关文章

Analysis of Nosocomial Infections in Selected Teaching Hospitals, Qazvin, Iran

Assessing The Role Of Hospital Ownership On Total Factor Productivity Changes In Qazvin Hospitals Using Malemquist s Index And DEA

A Study of the Physical Status of Emergency Wards’ Personnel in Hospitals Affiliated to Qazvin University of Medical Sciences through REBA (Rapid Entire Body Assessment) Method and Its Relation with Muscular and Skeletal Disorders in Qazvin, Iran

A Study of the Physical Status of Emergency Wards’ Personnel in Hospitals Affiliated to Qazvin University of Medical Sciences through REBA (Rapid Entire Body Assessment) Method and Its Relation with Muscular and Skeletal Disorders in Qazvin, Iran

"Occupational Exposure To Xylene In Workers, Employing At Pathology Wards Of Hospitals Belonging To The Qazvin University Of Medical Sciences "

Changes in treatment and mortality of acute myocardial infarction in Estonian tertiary and secondary care hospitals in 2001 and 2007

Pharmacoepidemiologic analysis of ST-elevation myocardial infarction reperfusion therapy at Saratov region hospitals of different types (Full english text)

Mortality in Dutch hospitals: Trends in time, place and cause of death after admission for myocardial infarction and stroke. An observational study

Pharmacotherapy analysis of acute ST-elevation myocardial infarction in hospitals of various types

Reducción de la mortalidad por infarto del miocardio en hospitales chilenos Reduction of acute myocardial infarction mortality in Chilean hospitals

更多...

The Correlation of Infectious and Inherent Agents with Acute Myocardial Infarction in Patients of Teaching Hospitals in Qazvin in 2013

DOI: 10.4236/oalib.1101656, PP. 1-11

Subject Areas: Cardiology

Keywords: Helicobacter pylori, Mycoplasma, ABO Blood Groups, Acute Myocardial Infarction, Qazvin

Full-Text   Cite this paper   Add to My Lib

Abstract

Background: Acute myocardial infarction (AMI) is one of the most common reasons of hospitalization in western countries. The rate of early mortality (the first 30 days) caused by AMI is about 30%. Many studies have introduced the infection with Helicobacter pylori and mycoplasma pneumonia as causes of AMI. However, some other studies on the effect of mycoplasma pneumonia, Helicobacter pylori, and blood group on the incidence of heart attack showed contradictions that might be due to the ethnical and racial heterogeneities. Therefore, this study was conducted to determine the correlation of the infection with Helicobacter pylori and mycoplasma pneumonia and blood group with AMI in Qazvin Province, Iran. Objectives: In this respect, the infection with Helicobacter pylori and mycoplasma pneumonia can be taken as a risk factor for AMI thereafter if there is a strong correlation between infection with Helicobacter pylori and mycoplasma pneumonia and AMI, and also the high-risk blood groups can be identified, and consequently, risk factors for AMI be reduced through early treatment. Materials and Method: This case-control study was performed in teaching hospitals in Qazvin. After completing the sample size in both groups (blood serum of 90 patients with a history of infarction as the case group and blood serum of 90 other people that matched for age and sex with the first group and had no history of infarction as the control group), the studies were performed to determine the correlation of AMI with mycoplasma pneumonia through the level of IgG antibody, with Helicobacter pylori through the level of relevant antibodies (IgA and IgG), and with blood groups through back-type method. Results: Men and women of the case group comprised 63.3% and 36.7%, respectively, and men and women of the control group comprised 67.8% and 32.2%, respectively. The level of Helicobacter pylori IgG was considered negative in 1.1%, borderline in 5.6%, and positive in 93.3% in the case group and negative in 5.6%, borderline in 10%, and positive in 84.4% in the control group. According to the Chi-square test, the difference between the two groups was significant (P < 0.05). However, the results showed that the level of Helicobacter pylori IgA was negative in 20%, borderline in 26.7%, and positive in 53.3% in the case group and negative in 12.2%, borderline in 20%, and positive in 67.8% in the control group. Based on the Chi-square test, the difference between the two groups in this regard was not significant (P > 0.05). The level of mycoplasma pneumonia IgG in the samples was negative in 17.8%, borderline in 5.6%, and positive in 76.7% in the case group and negative in 27.8%, borderline in 2.2%, and positive in 70% in the control group. Based on the Chi-square test, there was no significant difference between the two groups in this regard (P > 0.05). The results on testing the ABO blood groups showed that 23.3%, 21.1%, 27.8%, and 27.8% of the patients with AMI in the case group had the blood group O, AB, A, and B, respectively, and 30.7%, 13.6%, 34.1%, and 21.6% of the people in the control group had the blood group O, AB, A, and B, respectively. The analysis of results did not show a significant difference between case and control group in terms of ABO blood groups (P > 0.05). Conclusion and Recommendation: This study did not show a significant difference between the two groups in terms of the level of IgG except infection with Helicobacter pylori. However, more studies should be performed at local and national levels in order to find the role of risk factors of AMI in each region.

Cite this paper

Nejad, N. D. , Mostafaei, L. , Jahanbakhshi, F. , Rashvand, F. , Alipour, M. H. and Saroukhani, M. R. (2015). The Correlation of Infectious and Inherent Agents with Acute Myocardial Infarction in Patients of Teaching Hospitals in Qazvin in 2013. Open Access Library Journal, 2, e1656. doi: http://dx.doi.org/10.4236/oalib.1101656.

References

[1]  Miles, W.M., Williams, F.C. and Zipes, D.P. (2001) Cardiovascular Disease Andereoli TE Essentials of Medicine.
[2]  Pilotto, A., Rumor, F. and Franceschi, M. (1999) Lack of Association between Helicobacter pylori Infection and Extra- cardiac Atherosclerosis in Dyspepetic Elderly Subjects. Ageing, 28, 367-371.
[3]  Pasceri, V., Cammarota, G., Patti, G., et al. (1998) Association of Virulent Helicobacter pylori Strains with Ischemic Heart Disease. Circulation, 97, 1675-1679.
http://dx.doi.org/10.1161/01.CIR.97.17.1675
[4]  Laurial, A., Bloigu, A. and Nayha, S. (1999) Association of Helicobacter pylori Infection with Elevated Serum Lipids. Atherosclerosis, 142, 207-210.
http://dx.doi.org/10.1016/S0021-9150(98)00194-4
[5]  Pellicano, R., Mazzarello, M.G. and Morelloni, S. (1999) Acute Myocardial Infarction and Helicobacter pylori Seropositivity. International Journal of Clinical & Laboratory Research, 97, 1675-1679.
[6]  Pieniazek, P., Karczewska, E. and Duda, A. (1999) Association of Helicobacter pylori Infection with Coronary Heart Disease. Journal of Physiology and Pharmacology, 50, 743-751.
[7]  Rathbone, B., Martin, D. and Stephens, J. (1996) Helicobacter pylori Seropositivity in Subjects with Acute Myocardial Infarction. Heart, 76, 308-311.
http://dx.doi.org/10.1136/hrt.76.4.308
[8]  Grabczewska, Z., Nartowicz, E., Kubica, J. and Rosc, D. (2006) Endothelial Function Parameters in Patients with Unstable Angina and Infection with Helicobacter pylori and Chlamydia. European Journal of Internal Medicine, 17, 339-342.
http://dx.doi.org/10.1016/j.ejim.2006.02.005
[9]  Momiyama, Y., Ohmori, R., Tanigvchi, H., Nakamura, H. and Ohsuzu, F. (2005) Association of Mycoplasma Pneumonia Infections with Coronary Artery Disease and Its Interaction with Chlamydial Infection. Atherosclerosis, 180, 209-210.
[10]  Ponka, A., Jalanko, H., Ponka, T. and Stenvik, M. (1981) Association of Mycoplasma Pneumonia Infections with Coronary Artery Disease and Its Interaction with Chlamydial Infection. Annals of Clinical Research, 13, 429-432.
[11]  Maresh, H., Klimek, I. and Quineiliani, R. (1977) Myocardial Dysfunction and Hemolytic Anemia in a Patient with Mycoplasma pneumoniae Infection. Chest, 71, 410-413.
http://dx.doi.org/10.1378/chest.71.3.410
[12]  Mackay, A., Watt, J. and Jones, G. (1975) Myocarditis Associated with Mycoplasma pneumoniae Infection. Practioner, 390-392.
[13]  Ponka, A. (1979) Carditis Associated with Mycoplasma pneumoniae Infection. Acta Medica Scandinavica, 206, 77-86.
http://dx.doi.org/10.1111/j.0954-6820.1979.tb13473.x
[14]  Paz, A. and Potasman, I. (2002) Mycoplasma-Associated Carditis. Cardiology, 97, 83-88.
http://dx.doi.org/10.1159/000057677
[15]  Ramires, J.A. and Higuchi, M.L. (2002) Mycoplasma pneumoniae and Chlamydia pneumoniae Are Associated to Inflammation and Rupture of the Atherosclerotic Coronary Plaques. Revista Espanola de Cardiologia, 55, S2-S9.
[16]  Higuchi, M.L., Sambiase, N. and Palomino, S. (2000) Detection of Mycoplasma pneumoniae and Chlamydia pneumoniae in Rupeured Atherosclerotic Plaques. Brazilian Journal of Medical and Biological Research, 33, 1023-1026.
http://dx.doi.org/10.1590/S0100-879X2000000900005
[17]  Higuchi, M.L., Reis, M.M. and Sambiase, N.V. (2003) Coinfection with Mycoplasma pneumoniae and Chlamydia pneumoniae in Ruptured Plaques Associated with Acute Myocardial Infarction. Arquivos Brasileiros de Cardiologia, 81, 12-22.
http://dx.doi.org/10.1590/S0066-782X2003000900001
[18]  Bontti, P.O., Lerman, L.O. and lerman, A. (2003) Endothelial Dysfunction a Marker of Atherosclerotic Risk. Arteriosclerosis, Thrombosis, and Vascular Biology, 23, 168-175.
http://dx.doi.org/10.1161/01.ATV.0000051384.43104.FC
[19]  Higuchi, M.L. and Ramires, J.A. (2002) Infectious Agents in Coronary Atheromas: A Possible Role in the Pathogenesis of Plaque Rupture and Acute Myocardial Infarction. Revista do Instituto de Medicina Tropical de Sao Paulo, 44, 217-224.
http://dx.doi.org/10.1590/S0036-46652002000400007
[20]  Lutfullah, Akhtar, B., Quraishi, N.U.S., Hanif, A., Khan, B.Z. and Bukhshi, I.M. (2010) Association of ABO Blood Groups and Major Ischemic Heart Disease Risk Factors. Ann Anes, 16, 189-193.
[21]  Sayyah, S., Akbarian, M., Abdollah-Salimi, S., Tavakoli, M. and Pahlevan, A.A. (2012) AA Coexistence of Gastric Helicobacter pylori Infection and Coronary Artery Diseases in Qazvin (Iran). JQUMS, 16, 36-43.
[22]  Nakic, D., Vcev, A., Jovic, A., Patrk, J., Zekanovic, D., Klarin, I., et al. (2011) Helicobacter pylori Infection and Acute Myocardial Infarction. Collegium Antropologicum, 35, 781-785.
[23]  Danesh, J., Wong, Y. and Ward, M. (1999) Chronic Infection with Helicobacter pylori, Chlamydia pneumoniae or Cytomegalovirus: Population Based Study of Coronary Heart Disease. Heart, 81, 245-247.
http://dx.doi.org/10.1136/hrt.81.3.245
[24]  Bahar, M.A., Faghihi Kashani, A. and Haghighat, P. (2004) Association between Helicobacter pylori Infection and Coronary Heart Disease. Journal of Iran University of Medical Sciences, 39, 22-13.
[25]  Zhu, J., Quyyumi, A.A., Muhlestein, J.B., Nieto, F.J., Horne, B.D., Zalles-Ganley, A., Anderson, J.L. and Epstein, S.E. (2002) Lack of Association of Helicobacter pylori Infection with Coronary Artery Disease and Frequency of Acute Myocardial Infarction or Death. The American Journal of Cardiology, 89, 155-158.
http://dx.doi.org/10.1016/S0002-9149(01)02192-0
[26]  Mandell, M.A., Goggin, P.M. and Molineaux, N. (1994) Relation of Helicobacter pylori Infection and Coronary Heart Disease. Heart, 71, 437-439.
http://dx.doi.org/10.1136/hrt.71.5.437
[27]  Raygan, F., Khorasanifar, H., Momen Heravi, M., Arj, A. and Akbari, H. (2009) The Association between Acute Myocardial Infarction and Anti Helicobacter pylori Antibody. Zahedan Journal of Research in Medical Sciences, 11.
[28]  Rahnema, B., Zadegan, N. and Fatahi, E. (2001) Survey on the Association of Seropositivity of H. pylori IgG with Acute Myocardial Infarction. Journal of Kerman University of Medical Sciences, 8, 66-73.
[29]  Rahimi, B., Daneshpajouh, M. and Ahsani, S. (2001) Cardiovascular Disease and Chlamydia, Helicobacter pylori and Cytomegalovirus Infection. Pejouhandeh Quarterly Research Journal, 24, 331-334.
[30]  Azarkar, Z., Jafarnejad, M. and Sharifzadeh, G. (2011) The Relationship between Helicobacter pylori Infection and Myocardial Infarction. Caspian Journal of Internal Medicine, 2, 222-225.
[31]  Hara, K., Morita, Y., Kamihata, H., Iwasaka, T. and Takahashi, H. (2001) Evidence for Infection with Helicobacter pylori in Patients with Acute Myocardial Infarction. Clinica Chimica Acta, 313, 87-94.
http://dx.doi.org/10.1016/s0009-8981(01)00654-4
[32]  Bazzazi, H., Ghaemi, E. and Ramazani, M. (2010) The Seroepidemiology of the Chronic Infections in Patients with Myocardial Infarction in North of Iran. Journal of Research in Medical Sciences, 15, 116-119.
[33]  Basinkevich, A.B., Shakhnovich, R.M., Martynova, V.R., Kolkova, N.I., Rakovskaia, I.V. and Karazhas, N.V. (2003) Role of Chlamydia, Mycoplasma and Cytomegalovirus Infection in the Development of Coronary Artery Disease. Kardiologiia, 43, 4-9.
[34]  Hosinian, A., Habib Zadeh, S., Sadeghieh Ahari, S. and Mokhtar Por, A. (2007) The Study of Previous Contact with Chlamydia pneumoniae in Patients with Myocardial Infarction. Ardabil University of Medical Sciences & Health Services, 7, 35-40.
[35]  Pourahmad, M. (2005) A Study on the Relationship between Acute Myocardial Infarction and Chlamydia pneumoniae. Scientific Medical Journal of Ahwaz University of Medical Sciences, 4, 147-151.
[36]  Grau, A.J., Buggle, F., Heindl, S., Steichen-Wiehn, C., Banerjee, T., Maiwald, M., Rohlfs, M., Suhr, H., Fiehn, W., Becher, H. and Hacke, W. (1995) Recent Infection as a Risk Factor for Cerebrovascular Ischemia. Stroke, 26, 373-379.
http://dx.doi.org/10.1161/01.STR.26.3.373
[37]  Platt, D., Muhlberg, W., Kiehl, L. and Schmitt-Ruth, R. (1985) ABO Blood Group System, Age, Sex, Risk Factors and Cardiacinfarction. Archives of Gerontology and Geriatrics, 4, 241-249.
http://dx.doi.org/10.1016/0167-4943(85)90006-8
[38]  Stakishaitis, D.V., Ivashkiavichene, L.I., and Narvilene, A.M. (1991) Atherosclerosis of the Coronary Arteries and the Blood Group in the Population of Lithuania. Vrachebnoe Delo, 8, 55-57.
[39]  Whincup, P.H., Cook, D.G., Phillips, A.N. and Shaper, A.G. (1990) ABO Blood Group and Ischemic Heart Disease in British Men. BMJ, 300, 1679-1682.
http://dx.doi.org/10.1136/bmj.300.6741.1679
[40]  Akhund, I.A., Alvi, I.A., Ansari, A.K., Mughal, M.A. and Akhund, A.A. (2001) A Study of Relationship of ABO Blood Groups with Myocardial Infarction and Angina Pectoris. Journal of Ayub Medical College, Abbottabad, 13, 25-26.
[41]  Stakisaitis, D., Maksvytis, A., Benetis, R. and Viikmaa, M. (2002) Coronary Atherosclerosis and Blood Groups of ABO System in Women. Medicina, 38, 230-235.
[42]  Tarjan, Z., Tonelli, M., Duba, J. and Zorandi, A. (1995) Correlation between ABO and Rh Blood Group: Serum Cholesterol and Ischemic Heart Disease in Patients Undergoin Coronarography. Orvosi Hetilap, 136, 767-769.
[43]  Amirzadegan, A., Salarifar, M., Sadeghian, S., Davoodi, G., Darabian, C. and Goudarzynejad, H. (2006) Correlation between ABO Blood Group, Major Risk Factors and Coronary Artery Disease. International Journal of Cardiology, 110, 256-258.
http://dx.doi.org/10.1016/j.ijcard.2005.06.058
[44]  Kanbay, M., Yildirir, A., Ulus, T., Bilgi, M., Kucuk, A. and Muderrisoglu, H. (2006) Rhesus Positivity and Low High-Density Lipoprotein Cholesterol: A New Link? Asian Cardiovascular & Thoracic Annals, 14, 119-121.
http://dx.doi.org/10.1177/021849230601400208
[45]  Biancari, F., Satta, J., Pokela, R. and Juvonen, T. (2003) ABO Blood Group Distribution and Severity of Coronary Artery Disease among Patients Undergoing Coronary Artery Bypass Surgery in Northern Finland. Thrombosis Research, 108, 195-196.
http://dx.doi.org/10.1016/S0049-3848(03)00003-3
[46]  Ibrahim, S., Orhan, O., Vedat, D., Eren, G.S. and Mehmet, M.A. (2008) ABO Blood Group Distribution and Major Cardiovascular Risk Factors in Patients with Acute Myocardial Infarction. Blood Coagulation & Fibrinolysis, 19, 231- 234.
http://dx.doi.org/10.1097/MBC.0b013e3282f54522
[47]  Meade, T.W., Cooper, J.A., Stirling, Y., Howarth, D.J., Ruddock, V. and Miller, G.J. (1994) Factor VIII, ABO Blood Group and the Incidence of Ischaemic Heart Disease. British Journal of Haematology, 88, 601-607.
http://dx.doi.org/10.1111/j.1365-2141.1994.tb05079.x
[48]  Von Beckerath, N., Koch, W., Wemer, M., Mehilli, J., Gorchakova, O., Braunschomig, A., et al. (2004) ABO Locus O1 Allele and Risk of Myocardial Infarction. Blood Coagulation and Fibrinolysis, 15, 61-67.
http://dx.doi.org/10.1097/00001721-200401000-00010
[49]  Bronte-Stewart, B., Botha, M.C. and Krut, L.H. (1962) ABO Blood Groups in Relation to Ischemic Heart Disease. BMJ, 16, 1646-1650.
http://dx.doi.org/10.1136/bmj.1.5293.1646
[50]  Allan, T.M. and Dawson, A.A. (1968) ABO Blood Groups and Ischaemic Heart Disease in Men. Heart, 30, 377-382.
http://dx.doi.org/10.1136/hrt.30.3.377
[51]  Havlic, R.J., Feineib, M. and Garrison, R.J. (1969) Blood Groups and Coronary Heart Disease. Lancet, 294, 269-270.
http://dx.doi.org/10.1016/S0140-6736(69)90036-1
[52]  Rosenberg, L., Miller, D.R., Kawfman, D.W., Helmrich, S.P., Van de Carr, S., Stolley, P.D. and Shapiro, S. (1983) Myocardial Infarction in Women under 50 Years of Age. JAMA, 250, 2801-2806.
http://dx.doi.org/10.1001/jama.1983.03340200035025
[53]  Imam, F., Bhatti, A. and Lutfullah (2000) Blood Group as a Minor Risk Factor of Ischaemic Heart Disease. Medical Forum, 2, 1-4.
[54]  Khan, I.A., Farid, M. and Qureshi, S.M. (2005) Relationship of Blood Group Aye with Ischemic Heart Disease. Pakistan Journal of Medical Sciences, 44, 15-19.
[55]  Wazirali, H., Ashfaque, R.A. and Herzig, J.W. (2005) Association of Blood Group A with Increased Risk of Coronary Heart Disease in the Pakistani Population. Pakistan Journal of Physiology, 1, 10-12.
[56]  Abdollahi, A.A., Qorbani, M. and Salehi, A. (2009) ABO Blood Groups Distribution and Cardiovascular Major Risk Factors in Healthy Population. Iranian Journal of Public Health, 38, 123-126.
[57]  Shah, S.A.R. (1990) Frequency of Kell and ABO Blood Groups in a Section of Lahore Population. Pakistan Journal of Medical Research, 29, 134-137.
[58]  Khattak, I.D., Khan, T.M. and Khan, P. (2008) Frequency of ABO and Rhesus Blood Groups in District Sawat, Pakistan. Journal of Ayub Medical College Abbottabad, 20, 127-129.
[59]  Allan, T.M. (1976) ABO Blood Groups and Age Groups in Surgical Venous Thromboembolism. Atherosclerosis, 23, 141-142.
http://dx.doi.org/10.1016/0021-9150(76)90124-6
[60]  Jick, H. and Porter, J. (1978) Thrombophlebitis of the Lower Extremities and ABO Blood Type. Archives of Internal Medicine, 138, 1566-1567.
http://dx.doi.org/10.1001/archinte.1978.03630350088024
[61]  Gonzalez Ordonez, A.J., Medina Rodriguez, J.M., Martin, L., Alvarez, V. and Coto, E. (1999) The O Blood Group Protects against Venous Thromboembolismin Individuals with the Factor V Leiden but Not the Prothrombin (Factor II G20210A) Mutation. Blood Coagulation & Fibrinolysis, 10, 303-307.
http://dx.doi.org/10.1097/00001721-199907000-00013
[62]  Thompson, S.G., Kienast, J., Pyke, S.D.M., Haverkate, F. and van de Loo, J.C.W. (1995) Hemostatic Factors and the Risk of Myocardial Infarction or Sudden Death in Patients with Angina Pectoris. European Concerted Action on Thrombosis and Disabilities Angina Pectoris Study Group. New England Journal of Medicine, 332, 635-641.
http://dx.doi.org/10.1056/NEJM199503093321003
[63]  Green, D., Jarrett, O., Ruth, K.J., Folsom, A.R. and Liu, K. (1995) Relationship among Lewis Phenotype, Clotting Factors, and Other Cardiovascular Risk Factors in Young Adults. Journal of Laboratory and Clinical Medicine, 125, 334-339.
[64]  O’Donnell, J. and Laffan, M.A. (2001) The Relationship between ABO Histo-Blood Group, Factor VIII and von Willebrand Factor. Transfusion Medicine, 11, 343-351.
http://dx.doi.org/10.1046/j.1365-3148.2001.00315.x
[65]  Souto, J.C., Almasy, L., Muniz-Diaz, E., Soria, J.M., Borrell, M., Bayen, L., et al. (2000) Functional Effects of the ABO Locus Polymorphism on Plasma Levels of von Willebrand Factor, Factor VIII, and Activated Partial Thromboplastin Time. Arteriosclerosis, Thrombosis, and Vascular Biology, 20, 2024-2028.
http://dx.doi.org/10.1161/01.ATV.20.8.2024

Full-Text


comments powered by Disqus