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Segmental vitiligo and twenty-nail dystrophy: An unusual association
Rajashekar T,Singh Gurcharan,Rajkumar V
Indian Journal of Dermatology, Venereology and Leprology , 2008,

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Ethnobotanical survey regarding the management of liver disorders by Traditional healers of Vellore district, Tamil Nadu, India
T.Thirunarayanan,S.Rajkumar
International Journal of Pharmacology and Clinical Sciences , 2012,

Abstract: Background: The present study was based upon the ethnomedico-botanical survey on health practices by the tribal and non tribal village vaidyas (healers).Objectives: Present paper reports inventory of health practices on liver disorders used by vaidyas of Vellore district, Tamil Nadu, India. Materials and methods: A structured interview was conducted for 64 vaidyas covering areas like understanding the disease, perception about cause, symptoms, classification of this disease, diagnostic and prognostic methods used, treatment given, sources of plant materials used, process methods adopted, dosage, dietary practices followed and referral for further treatment. Results: More than 60% of the village vaidyas had clear understanding regarding the various aspects of liver diseases. The study identified 47 species of medicinal plants, 30 formulations and various dietary practices used by the vaidyas in the management of liver disorders. Conclusion: This study documents treatment and practices followed by vaidyas. Scientific studies done using these formulations/practices may help health practioners to practice evidence based medicine.

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Chromatographic finger print analysis of budmunchiamines in Albizia amara by HPTLC technique
T. Rajkumar, B.N.Sinha
International Journal of Research in Pharmaceutical Sciences , 2010,

Abstract: Recently, there has been an increase in the use of herbal drugs for healthcare. Herbal Medicine is a time-tested and valuable resource for healing. In India, the herbal drug market is about $ one billion and the export of plant based crude drugs is around $ 80 million. So it is absolutely essential to provide scientifically proven and evidence based herbal formulations for global acceptance. Chromatographic fingerprint symbolize the active chemical constituents of herbal medicines for desired therapeutic action. This study presents a simple, rapid and selective HPTLC method for separation and determination of Albizia amara. Albizia amara (Fabaceae) is the medicinal plant which has been used to treat piles, diarrhoea, gonorrhoea, leprosy, and leucoderma. The macro cyclic alkaloid Budmunchiamines is the main constituent which has been separated and identified by camag HPTLC. The coarsely dried powdered leaves were extracted with Petroleum Ether (60-80)0C by cold maceration, and hot percolation with 90% methanol for 72 h. TLC profile and HPTLC fingerprints were recorded by using silica gel GF254 as stationary phase. Separation was performed on pre-coated 10x10cm HPTLC Aluminium sheets. Sample volumes of (5μl) were applied to the 6 tracks contain bandwidth of 5mm and 10 secs/μl using a TLC applicator. The plates were developed using a mobile phase of Chloroform: diethylamine (86:22 v/v). The peak 2, 6 reveals that the presence of macro cyclic alkaloids Budmunchiamines L4, L5 were characterised and confirmed by FTIR, 1H NMR, MASS and CHN analysis. The results were compared with earlier reports. The developed HPTLC fingerprints will help the manufacturer for quality control and standardization of herbal formulations.

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Effect of early age thermal conditioning on expression of heat shock proteins in liver tissue and biochemical stress indicators in colored broiler chicken
M. Shanmugam,T. Thirunalasundari,U. Rajkumar
- , 2016,

Abstract: The present study was aimed at finding the effects of early age thermal conditioning on liver HSP 90 alpha, 70 and 60 mRNA expression and plasma biochemical parameters in colored broiler chicken. Chicks from two breeds (Naked neck and Punjab Broiler-2) were divided in to control (C) and heat exposed (H). The chicks were reared in controlled environmental chamber (25±1°C). H group chicks were exposed to 43±1o C for 6 hours during 5-7th day post hatch. Chicks from H group and a sample of chicks from control group (CE) were exposed to 43±1°C for 6 hours on 42nd day. On 7th and 42nd day chicks from each group were sacrificed for sample collection and processing. On 7th day the mRNA expression of all the three genes were significantly (P<0.05) higher in H group in both the breeds. On 42nd day CE group chicks had significantly (P<0.05) higher mRNA expression for all HSP genes compared to HE birds. T3 concentration was significantly (P<0.05) higher in H group birds in both the breeds at 7th day. The biochemical parameters significantly (P<0.05) varied between the C and H groups at 7th day. The biochemical parameters were significantly lower (P<0.05) in HE group birds compared to CE group birds after acute heat exposure on 42nd day. Based on the results of this study it can be concluded that early age thermal conditioning of chicks improves the thermo tolerance in post natal life in colored broiler chicken

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REVERSE GEAR MECHANISM FOR TWO WHEELER VEHICLES
P. LOGANATHAN,P.SOORIYA PRAKASH,R. RAJKUMAR,R. SUDHAKARAN,T.SUBASH, R.RAJKUMAR
- , 2018,

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Does "ichthyosis uteri" have malignant potential? : A case report of squamous cell carcinoma of endometrium associated with extensive ichthyosis uteri
Kanchan Murhekar, Urmila Majhi, V Sridevi, T Rajkumar
Diagnostic Pathology , 2008, DOI: 10.1186/1746-1596-3-4

Abstract: A 65-year-old multi-gravida presented with complaints of abdominal pain and postmenopausal bleeding per vagina for seven months. Her past medical history was insignificant with no history of tuberculosis, inflammatory conditions of the uterus or iatrogenically introduced substances in uterus. She had attained menopause about 15 years back.Gynecological examination revealed atrophic ectocervix flushed with vagina. The vagina appeared normal. Uterus was bulky of around 12 weeks and adnexae were unremarkable. Colposcopy showed schiller's unstained areas on anterior lip of cervix. Ultrasound abdomen showed endometrial thickness of 2.6 cms. and fluid in the endometrial cavity. Ectocervical biopsy showed strips of moderate to severe dysplastic stratified squamous epithelium. Endometrial curetting revealed strips of stratified squamous epithelium showing moderate dysplastic changes. No normal endometrium was seen. The pyometra was drained, following which the patient underwent type-II radical hysterectomy. The procedure was well tolerated and the postoperative period was uneventful.The hysterectomy specimen revealed thickened and widened endometrial cavity with gray white nodule in the sub-adjacent myometrium. The cervix showed no obvious growth. The cut-section of the right fallopian tube showed thickened mucosa. Both the ovaries did not show any gross abnormality.The sections revealed entire endometrium replaced by stratified squamous epithelium showing areas of heavy keratinization, koilocytic changes, nuclear hyperchromasia and moderate increase in nuclear-cytoplasmic ratio indicating low grade dysplastic changes in underlying ichthyosis uteri (Fig 1). Extensive sampling of endometrium revealed few atrophic endometrial glands beneath the dysplastic squamous epithelium (Fig 2). Focal invasive islands of atypical squamous epithelial cells were seen in superficial myometrium (Fig 3). In addition, myometrium showed few foci of adenomyosis. Section from the cervix showed mo

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Load Frequency Control Using Optimal PID Controller for Non-Reheat Thermal Power System with Tcps Unit
V.Shanmugasundaram,A.R Rajkumar,T.Jayabarathi
International Journal of Engineering and Advanced Technology , 2012,

Abstract: The main objective of Load Frequency Control (LFC) is to regulate the power output of electric generator within an area, in response to the changes in system frequency and tie-line loading. Thus, LFC helps in maintaining the scheduled system frequency and tie-line power interchange with other areas within the prescribed limits. Most LFCs are primarily composed of an integral and PID controller. The integrator gain is set to a level that compromises between fast transient recovery and low overshoot in the dynamic response of the overall system. This type of controller is slow and does not allow the controller designer to consider the possible changes in operating condition and non-linearity in the generator unit. Moreover, it lacks in robustness. FACTS are designed to overcome the limitations of present non-reheat thermal-thermal power systems and enhance the power system stability. One of the promising FACTS devices is the Thyristor controlled phase shifter (TCPS) to alleviate this difficulty. TCPS is connected in the tie-line to self-tune the parameters of integral and PID controller. Two area system, have been considered for simulation of the proposed TCPS connected integral and PID controller .The performance of the Conventional controller, TCPS connected Integral and PID controller have beenCompared through MATLAB Simulation. The qualitative and quantitative comparisons have been carried out for Integral, PID controllers. The dynamic of performanceresponses of Integral and PID controller with TCPS shows that in terms of settling Time, peak overshoot and steady state error are greatly improved than that of without TCPS.

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Unusual facial melanosis in viral fever
Shivakumar V,Okade Rajendra,Rajkumar V,Rajashekar T
Indian Journal of Dermatology , 2007,

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