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鼓膜切开联合地塞米松鼓室冲洗治疗分泌性中耳炎临床诊治分析
Clinical Diagnosis and Treatment of Secretory Otitis Media by Tympanic Membrane Incision Combined with Dexamethasone Tympanic Chamber Irrigation  [PDF]
张波
Advances in Clinical Medicine (ACM) , 2020, DOI: 10.12677/ACM.2020.108240
Abstract:
目的：在于分析、观察患者鼓膜切开联合地塞米松鼓室冲洗对治疗分泌性中耳炎的临床作用和效果。方法：对我科2016年10月至2019年10月收治的分泌性中耳炎(单耳型)患者92例，随机分为对照组和观察治疗组，每组46人。其中对照组予以鼓膜穿刺并联合地塞米松鼓室注射治疗，而观察组给予患者鼓膜切开联合地塞米松鼓室冲洗治疗，均为1次/3天，连续3次，方法：分析2组患者的实际临床观察疗效。分析结果：与对照组相比，观察组治疗总有效率显著提高(p < 0.05)。疗效分析结论：观察组鼓膜切开联合地塞米松鼓室冲洗治疗分泌性中耳炎的有效率优于鼓膜穿刺联合地塞米松鼓室注射，能较好地提高分泌性中耳炎治疗的临床疗效。
Objective: To analyze and observe the clinical effect and effect of tympanic membrane incision combined with dexamethasone tymp irrigation on the treatment of secretory otitis media. Methods: 92 patients with secretory otitis media (single ear type) admitted in our department from October 2016 to October 2019 were randomly divided into the control group and the observation group, 46 in each group. The control group was treated with tympanic membrane puncture and combined with dexamethasone tympanic injection, while the observation group was treated with tympanic membrane incision and combined with dexamethasone tympanic lavage, all of which were 1/3 days, 3 times in succession, and the clinical efficacy of 2 groups was analyzed. Results: The total effective rate of treatment in the observation group was significantly higher than that in the control group. Conclusions: The effective rate of tympanic membrane incision combined with dexamethasone tympanic lavage in the observation group was better than that of tympanic membrane puncture combined with dexamethasone tympanic chamber injection, which could improve the clinical effect of secretory otitis media.
大埋深高应力软岩巷道围岩支护技术研究
The Research of Depth High Stress Soft Rock Roadway Supporting  [PDF]
张远波
Mine Engineering (ME) , 2015, DOI: 10.12677/ME.2015.33019
Abstract:
以深部软岩巷道为研究背景，对某矿西盘区底板措施巷巷道表面位移进行监测，监测结果表明巷道围岩出现非线性大变形、锚索破断及支架扭曲变形等现象。利用FLAC3D对巷道围岩进行数值模拟，得出软岩巷道围岩变形属于给定变形，巷道支护体不仅要提供足够的支护强度，还必须适应软岩巷道大变形，据此提出可接长锚杆协调支护技术，使稳定后顶板下沉量在200~250 mm之间，两帮相对移近量在200 mm上下，得到预期的支护效果。
In this study, the deep soft rock roadway was as the research background. The roadway of the mine’s west bottom panel measure’s lane surface displacement was monitored. Data show that the rock roadway deformation is nonlinear large deformation of surrounding rock deformation and widespread cable breakage and other support bracket distorted body damage phenomena. Using FLAC3D software to simulate on the rock roadway, we obtained that the deformation of soft rock roadway belonged to given deformation. Roadway body not only has to provide sufficient supporting strength, but also must adapt to large deformation of soft rock roadway. Hereby, proposing the coordinated supporting technology with docking bolt, making the roof sinkage between 200 and 250 mm when it is stable and the relative two sides moving quantity in 200 mm up and down, getting the expected supporting effect.
哲学的“前形而上学”视域中的《金瓶梅》解读与反思
Interpreting and Reflecting for The Golden Lotus in the Perspective of “Pre-Metaphysics” of Philosophy  [PDF]
张波, 王钊
Advances in Philosophy (ACPP) , 2021, DOI: 10.12677/ACPP.2021.102013
Abstract:
明人小说《金瓶梅》是第一部文人独创的非历史演绎的话本小说。从哲学的“前形而上学”视域来解读审视《金瓶梅》这一奇书，它生动地讲述了特定历史条件下一个关于人的性、欲、情、爱的故事。肉体获得灵性才会有人性，只有让灵与肉获得和谐统一、以灵去统御肉，自然之性欲才会成长为人性之情爱，它才通之乎美达之乎善。该书作为活的社会存在的标本，反映了中国传统社会作为“君主集权的等级制的男权宗法社会”的鲜明特征，让人看到权力崇拜与暴力崇拜所构成的中国传统社会的文化底色。它预示了野蛮的不平等的反人性的权力结构及其社会制度必然会腐败、必然要灭亡的命运。
The Golden Lotus, which was written in The Ming Dynasty, is the first non-historical interpretation, story-telling and scholars’ original creation novel in the history of Chinese literature. According to the view of “pre-metaphysics” of philosophical, The Golden Lotus shows us vividly that it was a masterpiece which was combined with human’s sex, desire, emotion and love in specific historical conditions. The body will become humanity after achieving spiritually, using the way to combine with the spirituality and the body harmoniously, and allowing the spirituality to get the leadership of the body, then the desire of the sex will change into the love of human nature and finally turn to be perfect and goodness. As a specimen of living social existence, The Golden Lotus not only reflects the distinct characteristics of “the male-dominated patriarchal society of social hierarchy in the monarchy of ancient China”, but also shows the background of Chinese traditional society which was composed by the worship of power and violence. Furthermore, it indicates that the destiny of power structure and social system which was barbarous, unequal and anti-human, has an inevitable outcome to corruption and perdition.
情感异化与机器人崛起：后人类时代的人机共同体困境
Emotional Alienation and the Rise of the Robots: The Human-Machine Community Dilemma in the Post-Human Era  [PDF]
张少波
World Literature Studies (WLS) , 2025, DOI: 10.12677/wls.2025.132028
Abstract: 文章以石黑一雄的《克拉拉与太阳》为蓝本，以后现代理论为依托，探讨后人类时代技术对人类情感的异化及人机共同体的伦理困境。文章指出，技术对身体的介入虽带来功能强化，却也导致情感疏离与本体性危机。而后情感文化的蔓延则使情感沦为机械化的虚假符号，加剧了人际关系的空洞化。人工智能克拉拉虽展现出类人的关怀与牺牲精神，但其情感本质仍是算法驱动的数字模拟，缺乏人类情感的灵韵。人类对克拉拉的承认始终基于工具理性，否认其情感真实性，折射出人机共同体的单向性与不稳定性。文章认为技术无法替代人类情感的独特性与复杂性，呼吁在技术与人性的张力中寻求平衡，同时摒弃人类中心主义，重构后人类时代人机共同体伦理，以实现从“人之死”到“后人类之生”的转变。
Based on Kazuo Ishiguro’s Klara and the Sun, this article explores the alienation of human emotions by technology and the ethical dilemma of the human-machine community in the post-human era based on post-modern theories. The article points out that although the intervention of technology in the body brings about functional enhancement, it also leads to emotional alienation and ontological crisis. The spread of post-emotional culture has reduced emotions to mechanized false symbols, exacerbating the emptiness of interpersonal relationships. Although the artificial intelligence Klara shows human-like care and sacrifice, its emotional nature is still an algorithm-driven imitation, lacking the aura of human emotions. Human recognition of Klara is rooted in instrumental rationality, but still denies its emotional authenticity, reflecting the unidirectionality and instability of the human-machine community. The article argues that technology cannot replace the uniqueness and complexity of human emotions, and calls for finding a balance between technology and humanity, abandoning anthropocentrism, and reconstructing the ethics of human-machine community in post-human era to realize the transition from “death of men” to “life of post-human”.
乌司他丁对感染所致急性循环衰竭患者微循环的影响
UTI Influence on Microcirculation in Patients with Acute Circulatory Failure Caused by Infection  [PDF]
张赛, 孙运波, 姚波
Advances in Clinical Medicine (ACM) , 2020, DOI: 10.12677/ACM.2020.105113
Abstract:
目的：探究乌司他丁能否通过改善感染所致急性循环衰竭患者的微循环灌注从而改善其预后。方法：1)收集2018~5至2019~12入住青岛大学附属医院综合ICU及急诊ICU感染所致急性微循环衰竭患者共50例，随机将其分为对照组25例(仅接受常规治疗)和实验组25例(乌司他丁 + 常规治疗)。2) 分别用LH-SDF-1型SDF观测仪(徐州利华电子科技发展有限公司)观察对照组和实验组患者0 h、3 h、6 h、12 h、24 h、48 h、72 h的舌下微循环状态，分别计算出相应微血管流动指数(MFI)、总血管密度(TVD)、灌注血管密度(PVD)、灌注血管比例(PPV)。3) 分别统计出两组患者的各自的72小时ΔSOFA、30天全因病死率。4) 所获得的数据采用SPSS22软件针对各组定量数据进行独立样本t检验，率的比较采用χ2检验，P < 0.05视为有统计学差异。结果：1) 乌司他丁组的用药48小时后微循环指标明显高于常规对照组(P均 < 0.05，详见正文)。2) 乌司他丁组的72小时ΔSOFA要明显高于常规对照组(P = 0.005, t = 2.980)；乌司他丁组中30天死亡率为8%，常规对照组中30天死亡率为24%。结论：与常规对照组治疗相比，加用乌司他丁能够改善感染所致急性循环衰竭患者用药后48小时的所有微血管指标，能够明显地改善72小时SOFA评分，从而改善30天预后。
Objective: To explore whether Ulinastatin (UTI) can improve microcirculation in patients with acute circulatory failure caused by infection to improve their prognosis. Methods: 1) Collect 50 patients with acute circulatory failure caused by infection which were admitted to intensive care unit in Affiliated Hospital of Qingdao University during 2018-5 to 2019-12. They were randomly divided into 25 control group and 25 UTI group. The control group received conventional treatment, and the UTI group was on the basis of conventional therapy plus UTI. 2) Use LH-SDF-1 type SDF observer (Xuzhou Lihua Electronic Technology Development Co., Ltd.) to observe control group and UTI group patients’ sublingual microcirculation at the time point of 0 h, 3 h, 6 h, 12 h, 24 h, 48 h, 72 h, then calculate microvascular flow index (MFI), total vessel density (TVD), perfused vessel density (PVD), proportion of perfused vessels (PPV). 3) The 72 hours of ΔSequential Organ Failure Assessment (ΔSOFA) and 30 days of all-cause mortality in the two groups were calculated. 4) Independent samples t-test was performed for each group of quantitative data by the software of SPSS 22nd edition. χ2 test was used to compare rates for each group. P < 0.05 was considered statistically significant. Results: 1) The results show that 48 hours microcirculatory situation in the UTI group is higher than the control group (P < 0.05, see in the next). 2) The 72 hours ΔSOFA in the UTI group is higher than the control group (P = 0.005, t = 2.980). The 30-day mortality rate in the UTI group is 8% and in the control group is 24%. Conclusion: Compared with the conventional control group, plus UTI can improve all microcirculation indicators after dosing for 48 hours. It can also improve 72 hours SOFA scores obviously thereby improving the prognosis of 30 days.
基于改进人工鱼群算法的最短路径问题研究
An Modified Artificial Fish Swarm Algorithm for the Optimal Routing Problem  [PDF]
张航, 杨清波
Computer Science and Application (CSA) , 2012, DOI: 10.12677/CSA.2012.22018
Abstract: 最短路径问题是交通网络分析中的一个重要问题。本文在分析基本鱼群算法在求解交通网络两点之间最短路径的基础上，针对其准确性和处理时间的不足，对人工鱼初值和行为进行了改进，提出了改进的人工鱼群算法。仿真实验表明提出的方法较原始鱼群算法能更准确、更快速地找到交通路网中任意两点间的最短路径。
Search for the shortest path in transportation network is one of the most important problem of ITS. This pa- per analyzes the basic Artificial Fish Swarm Algorithm and presents an improved algorithm on initialize population and behavior. The results of the experimentation proved that the improved algorithm could find the shortest path more ac- curately and quickly than the basic algorithm, and it is feasible.
集约养殖粪污能源工程的经济性分析
The Economical Efficiency of Excrement Energy Engineering in Breeding Industry  [PDF]
王宇波, 张珍
Sustainable Development (SD) , 2016, DOI: 10.12677/SD.2016.63028
Abstract:
畜牧业集约化发展，随之带来的污染问题越来越严重，对农业生态和食品安全造成威胁，也成为妨碍禽畜养殖产业健康发展的重要因素。本文运用成本效益模型分析德清源沼气发电工程的经济可行性，得出集约养殖企业可以通过沼气发电能源工程串起粪污综合利用的循环农业产业链，实现畜牧业污染物从“治”到“化”的转变。同时，在分析中得出养殖业沼气发电存在的经济效益未凸显、电量收购、补贴及产业链断裂等问题，针对问题对集约养殖沼气发电提出几点建议。
With the development of stockbreeding, a lot of problems have been brought. The pollution is more and more serious, which has become a threat to the agricultural ecology and food safety. The pollution seriously affected the healthy development of the breeding industry simultaneously. In this paper, through the empirical analysis of Deqingyuan biogas power electricity generation en-gineering, it resulted that the breeding industry could make up a circulation agriculture industry chain by the project of biogas power electricity generation and change the situation of the livestock pollution from “cure” to “utilization”. At the same time, through the analysis, there are several problems, such as the economic benefits not reflected, the acquisition of power, subsidies and industrial-strand breaks. At last, there will be some suggestions to the biogas power electricity generation in breeding industry.
“双创”背景下经管类课程实践教学模式探究——基于Seminar教学法与微案例教学法交叉应用
Research on Practical Teaching Mode of Economic Management Courses in the New Era of Innovative and Entrepreneurial—Based on Cross-Application of Seminar Teaching Method and Micro-Case Teaching Method  [PDF]
张松波, 韩丹
Advances in Social Sciences (ASS) , 2019, DOI: 10.12677/ASS.2019.88197
Abstract:
我国经济和社会的发展对高等专业人才从各方面都提出新的要求，在此背景下，加强高等教育改革的重要性和紧迫性也日益凸显出来。而在高等教育改革过程当中，创新创业教育一直处于非常重要的位置，目前各高校对经管类专业人才的教学模式在培养学生创新创业能力方面还存在较大的改进空间，从而教学模式的滞后性在一定程度上会降低经管类课程的教学质量，并影响学生创新创业能力的提高。在当前大学本科教学改革方面，国内外运用最普遍的教育改革方法是Seminar与案例教学法。传统的教学方法是采用“老师传授–学生接受”的单向模式，而Seminar教学法与案例教学法都以改变这种传统单向教学模式为出发点，力图在课程教学中实现“教学相长”。本文以经管类课程为研究对象，基于创新创业教育的大背景，旨在探索Seminar教学法与微案例教学法的交叉运用，希望能够提高课程的授课效果。
China’s economic and social development has put forward new requirements for higher professionals from all aspects. Under this background, the importance and urgency of strengthening the reform of higher education have become increasingly prominent. In the process of higher education reform, innovation and entrepreneurship education has been in a very important position. At present, there is still much room for improvement in cultivating students’ innovation and entrepreneurship ability in the teaching mode of economic and management professionals in various universities, so the lag of teaching mode will reduce the teaching quality of economic and management courses to some extent, and affect the improvement of students’ innovation and entrepreneurship ability. In the current un-dergraduate teaching reform, the most common educational reform methods used at home and abroad are Seminar and case teaching method. The traditional teaching method adopts the one-way mode of “teacher-teacher-student acceptance”, but the Seminar teaching method and case teaching method both take changing the traditional one-way teaching mode as the starting point and try to achieve “teaching while learning” in the course teaching. Taking economic management courses as the research object, this paper aims to explore the cross application of Seminar teaching method and micro-case teaching method based on the background of innovation and entrepreneurship education, hoping to improve the teaching effect of the course.
自噬在食管鳞癌中的研究进展
Research Progress of Autophagy in Esophageal Squamous Cell Carcinoma  [PDF]
张云龙, 王振波
Advances in Clinical Medicine (ACM) , 2020, DOI: 10.12677/ACM.2020.1010350
Abstract:
自噬属于细胞程序性死亡，通过降解入侵的病原体、清除受损的细胞器及多余的脂质，降解的物质重新被机体利用以维持细胞稳态和器官完整性的作用。随着对自噬研究的逐渐深入，发现其与食管鳞癌的发生、发展密切相关，不仅在肿瘤的发生前期起着抑制作用，而且在食管鳞癌的发展中起到了促进作用。近年来发现在食管鳞癌的治疗中，通过对自噬的干预有着明显的效果。本文主要综述了细胞自噬的过程和机制、在食管鳞癌中的作用以及参与食管鳞癌治疗的研究进展。
Autophagy is a kind of programmed cell death. By degrading invading pathogens, removing damaged organelles and excess lipids, the degraded substances are reused by the body to maintain cell homeostasis and organ integrity. With the deepening of the study on autophagy, it is found that it is closely related to the occurrence and development of esophageal squamous cell carcinoma, which not only plays an inhibitory role in the early stage of the occurrence of tumors, but also plays a promoting role in the development of esophageal cancer. In recent years, it has been found that the intervention of autophagy has obvious effects on the treatment of esophageal cancer. This paper mainly reviews the process and mechanism of autophagy, its role in esophageal cancer and autophagy’s involvement in the treatment of esophageal cancer.
儿童阻塞型睡眠呼吸暂停低通气综合征诊断及治疗的研究进展
Overview on Diagnosis and Treatment of Obstructive Sleep Apnea-Hypopnea Syndrome in Children  [PDF]
张雅丽, 崔晓波
Advances in Clinical Medicine (ACM) , 2021, DOI: 10.12677/ACM.2021.116375
Abstract: 阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea-hypopnea syndrome, OSAHS)主要是由于睡眠时上气道部分或完全阻塞扰乱正常通气而出现呼吸暂停或低通气，是一类较为常见的疾病。儿童腺样体/扁桃体增生肥大导致的上气道狭窄是儿童阻塞性睡眠呼吸暂停综合征的主要原因，诊断主要依据主观症状、X线、电子鼻咽镜和睡眠监测等检查。对于儿童OSAHS的治疗方式多样，以手术治疗和药物治疗较为常见。本文将对目前儿童OSAHS的多种诊断及治疗方法的研究进展作一综述。
Obstructive sleep apnea-hypopnea syndrome (OSASH) in children is partial upper airway obstruction and/or complete upper airway obstruction leading to disrupt ventilation result in hypopnea and/or apnea during sleep. OSAHS is a common illness. Upper airway stenosis caused by adenoid/tonsil hyperplasia in children is the main cause of obstructive sleep apnea syndrome in children. The diagnosis is mainly based on subjective symptoms, X-ray, electronic nasopharyngoscopy and polysomnography. There are various treatment methods for children OSAHS, and surgical treatment and drug treatment are more common. This article will review the research progress of multiple diagnosis and treatment methods of OSAHS in children.
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