Total of 10 articles.
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May 19, 2023Open AccessArticle
Infections from parasitic nematodes (or roundworms) contribute to a significant disease burden and productivity losses for humans and livestock. The limited number of anthelmintics (or antinematode drugs) available today to treat these infections are rapidly losing their efficacy as multidrug resistance in parasites becomes a global health challenge. We propose an engineering approach to discover an anthelmintic drug combination that is more potent at killing wild-type Caenorhabditis elegans wor...
Neuroscience
Marine Biology
Toxicology
Taxonomy
Microbiology
Ecosystem Science
Biodiversity
Developmental Biology
Bioengineering
Environmental Sciences
Animal Behavior
Agricultural Science
Biotechnology
Computational Biology
Food Science & Technology
Parasitology
Plant Science
Synthetic Biology
May 19, 2023Open AccessArticle
In this paper, we present a movement-based assay to observe adaptability in Caenorhabditis elegans locomotion behavior. The assay comprises a series of sinusoidal microchannels with a fixed wavelength and modulating (increasing or decreasing) amplitude. The channel width is comparable to the body diameter of the organism. Worms are allowed to enter the channel from the input port and migrate toward the output port. Within channel sections that closely match the worm's natural undulations, the wo...
Animal Behavior
Agricultural Science
Veterinary Medicine
Parasitology
Plant Science
Soil Science
Biodiversity
Bioengineering
May 19, 2023Open AccessArticle
In this paper, we explore the use of microfluidic paper-based analytical devices (？PADs) to study the behavior of Caenorhabditis elegans. We show how these devices can be fabricated on paper and plastic substrates, as well as how to load, visualize, and transfer single and multiple nematodes. We also demonstrate the use of anthelmintic drug, levamisole, to perform chemical testing on C. elegans. Furthermore, we provide a custom program that is able to recognize individual worms on the ？PADs in r...
Animal Behavior
Computational Biology
Microbiology
Cell Biology
Parasitology
Plant Science
Soil Science
Developmental Biology
Bioengineering
Environmental Sciences
Biophysics
May 19, 2023Open AccessArticle
All life forms use a seamless integration of physical and chemical sensing mechanisms to enhance their performance and survival skills. To mimic the integrative sensing abilities found in nature, there is a significant interest in developing wearable devices that can smartly track the physiological and biochemical signals of the human body. Progress in wearable physical sensors has been remarkable giving rise to a number of consumer electronics products meant to measure parameters related to act...
Electric Engineering
Green Chemistry
Electrochemistry
Biological Chemistry
Mathematical Biology
Biochemistry
Bioengineering
Bioinformatics
Fundamentals of Material Science
Biophysics
Environmental Sciences
Functional Materials
Chemical Engineering & Technology
Genomics
Computational Biology
Plant Science
Synthetic Biology
Materials Engineering
Analytical Chemistry
May 19, 2023Open AccessArticle
The objective of present study was to evaluate preliminary phytoconstitutents and in-vitro antioxidant potential of Lepidagathis cuspidata. Methanolic and aqueous extract of aerial part of plants was prepared and tested for the presence of different phytoconstitutents. The in-vitro antioxidant potential of extract were evaluate by different in-vitro methods. TLC of extracts were performed by using various solvent systems. The present study revealed that the MELC and AELC contained flavonoids, gl...
Plant Science
Aug 15, 2016Open AccessArticle
Natural antioxidants inhibit the adverse effects of the Reactive Oxygen Species produced in living things and enable to survive. Depending on this principle, humans started using some plant products to cure from various diseases. Natural products have proved of great health impact on human traditionally and scientifically. Moreover, the research has so far done in the field of natural antioxidants. Therefore, antioxidants have been traditionally used as well as experimentally proved beneficial. ...
Biological Materials
Biological Chemistry
Medicinal Chemistry
Plant Science
Biochemistry
Aug 09, 2016Open AccessArticle
Heritability estimates provide information about the traits that are
transmitted from parents to their offsprings and it has a crucial role in selection
criteria to improve grain yield. The purpose of the present study was to compute
heritability and genetic advance of seven F2 populations derived through cross
combinations of five parental varieties/lines of bread wheat Iqbal-2000, Lasani-
2008, 9444, 9432 and 9436. Data were recorded for seven metric traits: plant
height, days to heading, flag...
Agricultural Science
Plant Science
Jul 09, 2015Open AccessArticle
High temperature and salinity are the major ecological factors challenging crop productivity in the arid and semiarid regions of the world. Effects of high temperature (43-45°C) and salt stress (0.6 M) on Macrotyloma uniflorum (Lam.) Verdc. (Horse gram), were evaluated in terms of antioxidants and antioxidant enzymes. Both treatments caused typical stress responses in this tropical leguminosae. Oxidative stress indicators such as H2O2, TBARS, and proline were significantly elevated. Similarly, t...
Agricultural Science
Plant Science
Biochemistry
Jul 09, 2015Open AccessArticle
Rubus fruticosus L. is a shrub famous for its fruit called blackberry fruit or more commonly blackberry. The fruit has medicinal, cosmetic and nutritive value. It is a concentrated source of valuable nutrients, as well as bioactive constituents of therapeutic interest highlighting its importance as a functional food. Besides use as a fresh fruit, it is also used as ingredient in cooked dishes, salads and bakery products like jams, snacks, desserts, and fruit preserves. R. fruticosus contains vit...
Biological Materials
Diabetes & Endocrinology
Green Chemistry
Biological Chemistry
Evidence Based Medicine
Gastroenterology & Hepatology
Toxicology
Taxonomy
Clinical Trials
Biochemistry
Bioinformatics
Biophysics
Environmental Sciences
Agricultural Science
Food Science & Technology
Translational Medicine
Plant Science
Analytical Chemistry
Jan 15, 2015Open AccessArticle
The developed protocol describes a cheaper, quicker and reliable method for the isolation of pure DNA from medicinal herbs, such as Ammi majus, which produces the secondary metabolites xanthotoxin and berganpectane having immense medicinal importance. Use of CTAB, liquid nitrogen and EDTA in different isolation protocols analyzed for A. majus, all were ended with polysaccharide and protein contamination with low purity of DNA (A260/280 = 1.3 – 1.6), revealed a need for method modification for th...
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