superior vena cava syndrome is obstruction of blood flow through the superior vena cava (svc). it is most commonly caused by neoplasm, especially lung cancer. an obstructed svc initiates collateral venous return to the heart from the upper half of the body and the classic symptoms and signs become obvious. superior vena cava síndrome is a rare cause of ocular manifestations. we report a case of periorbital swelling, conjunctival edema an orbital proptosis in a male patient presenting malignant superior vena cava obstruction.