it has been reported the existence of an association between chronic viral hepatitis c and type 2 diabetes mellitus, probably as a manifestation of the chronic hepatic disease and/or one of its extra-hepatic manifestations. recently, it has been reported the appearance of type 1 diabetes mellitus after treatment with interferon-alpha, associated with the appearance of anti-pancreatic antibodies or with an increase in their titration. we pretend to illustrate a severe case of new-onset type 1 diabetes mellitus, 5 months after combined treatment with interferon-alpha and ribavirin. our objective is to enhance the importance of evaluate the risk of developing diabetes mellitus with the treatment.
