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-  2018 

高强度聚焦超声脑肿瘤治疗焦域温度均匀分布调控的数值仿真研究

DOI: doi:10.7507/1001-5515.201802009

Keywords: 高强度聚焦超声, 平台式温度分布, 焦域调控

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Abstract:

在高强度聚焦超声(HIFU)脑肿瘤治疗过程中需严格控制治疗温度。本研究通过调控相控换能器激励信号实现了焦域温度均匀分布的目的。首先,本文利用志愿者头部计算机断层扫描(CT)数据和 82 阵元相控换能器建立开颅 HIFU 治疗脑肿瘤的三维数值仿真模型,通过叠加聚焦于两个设定目标点的信号并调控两信号间激励时间差和幅值,研究其对 HIFU 焦域温度分布及焦域形状大小的调控。研究结果表明,两目标点间距离在一定范围内通过调节两激励信号的激励时间差和幅值可以实现焦域内温度均匀分布,同时可调控焦域形状和体积大小。本文研究的仿真结果或可为 HIFU 安全有效地应用于临床治疗提供理论方法和参考

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