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-  2018 


DOI: 10.13543/j.bhxbzr.2018.05.006

Keywords: 光接枝,活性聚合,可见光,酶固定化,细胞包覆,
,living polymerization,visible light,enzyme immobilization,cell coating

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Abstract:Photo-induced living graft polymerization has become one of most important surface modification methods due to its advantages of simple operation, low activation energy and spatial/temporal controllability. Compared to the more common UV initiation systems, visible light irradiation has lower energy and has no adverse effects on biologically active substances. Based on the results of two decades of research in the photografting field, researchers in Organic Materials Surface Science and Engineering Lab in Beijing University of Chemical Technology have developed a novel visible light-induced living graft polymerization strategy based on derivative of thioxanthone. Here we systematically describe the mechanism of this method and its application in enzyme immobilization, biochip formation and cell encapsulation. Finally, possible future developments in this field are discussed.


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