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-  2018 


DOI: 10.13543/j.bhxbzr.2018.05.011

Keywords: 糖苷类化合物,糖基转移酶,天然产物,糖基化反应,
,glycosyltransferase,natural product,glycosylation

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Abstract:Many natural products are active ingredients in traditional Chinese medicines and have good pharmacological activities. Glycosides, a class of biological molecules derived from the glycosylation of natural products, have attracted significant attention due to their ability to enhance the stability, solubility or bioavailability of natural products. In the past, glycosides have been generally synthesized by chemical synthesis or extracted from plants. In recent years, the utilization of glycosyltransferases to synthesize glycosides has become a major area of research. Glycosyltransferases are key enzymes in the synthesis of glycosides. This review summarizes recent advances in the use of glycosyltransferases in glycoside synthesis, and is expected to provide some guidelines for the future industrialization of glycoside synthesis using glycosyltransferase.


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