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-  2018 

Keggin 型磷钨酸盐修饰碳糊电极传感多巴胺的研究
Synthesis of Keggin Polyoxometalates Modified Carbon Paste Electrode as A Sensor for Dopamine Detection

DOI: 10.13208/j.electrochem.180405

Keywords: 多酸,多巴胺,电化学传感器,碳糊电极,循环伏安法,
,dopamine,electrochemical sensors,carbon paste electrode,cyclic voltammetry

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摘要 多金属氧酸盐作为一类阴离子簇合物,由于其结构的多样性和尺寸大小的可调变性,在电化学、催化和药学等领域引起了人们的广泛关注.本文制备了多酸Co(C15N6H12)2[PW12O38]·5H2O(Co[PW12O38])修饰碳糊电极并通过电化学阻抗谱、循环伏安法以及差分脉冲伏安法对多巴胺的传感性能进行了研究.对其制备条件和检测条件分别进行了优化.在优化条件下,制备的传感器对多巴胺具有良好的选择性和灵敏度的检测能力.多巴胺的线性响应范围为8.0x10-6 mol·L-1至3x10-5 mol·L-1,灵敏度为0.039 μA·(μmol·L-1)-1,检出限(S/N=3)为5.4 x10-6 mol·L-1. 制备的多酸修饰碳糊电极用于检测多巴胺表现出良好的稳定性和重现性,并且对抗坏血酸、尿酸等常见的干扰物质,具有良好的抗干扰性. 多酸修饰的碳糊电极制备过程简单方便,成本低,传感性能良好,对应用于电化学传感器检测多巴胺具备潜在的应用前景


[1]  Doron M, Nir G. Dopamine dysregulation syndrome, addiction and behavioral changes in Parkinson’s disease[J]. Parkinsonism & Related Disorders, 2008, 14(4): 273-280.
[2]  Stewart A J, Hendry J, Dennany L. Whole blood electrochemiluminescent detection of dopamine[J]. Analytical Chemistry, 2015, 87(23): 11847-11853.
[3]  Xu W J, Jiao C X. A review of preparation and application of carbon paste electrode and chemically modified carbon paste electrode[J]. Applied Chemicals, 2010, 39(5): 755-757
[4]  Li N, Huang R D. Six new inorganic-organic hybrids based on rigid triangular ligands: Syntheses, structures and properties[J]. Journal of Solid State Chemistry, 2016, 233: 320-328.
[5]  Subbiah A, Liu G, Li C Z. Simultaneous detection of dopamine, ascorbic acid, and uric acid at electrochemically pretreated carbon nanotube biosensors nanomedicine[J]. Biology & Medicine, 2010, 6(1): 52-57.
[6]  Celina M M, Tamyris Paschoal P, Daniela B, et al. Monoamine oxidase B layer-by-layer film fabrication and characterization toward dopamine detection[J]. Materials Science & Engineering C, 2016, 58: 310-315.
[7]  Du J, Yue R R, Ren F F, et al. Novel graphene flowers modified carbon fibers for simultaneous determination of ascorbic acid, dopamine and uric acid[J]. Biosensors & Bioelectronics, 2014, 53(4): 220-224.
[8]  Ren W(任旺), Zhang Y(张英), Li M J(李敏娇). Simultaneous determination of dopamine (DA) and epinephrine (EP) at CA/GC electrode[J]. Journal of Electrochemistry(电化学), 2011, 17(3): 343-346.
[9]  Omwoma S, Chen W, Tsunashima R, et al. Recent advances on polyoxometalates intercalated layered double hydroxides: From synthetic approaches to functional material applications[J]. Coordination Chemistry Reviews, 2014, 258: 58-71.
[10]  Wang G J, Chang L D, Volkow N D, et al. Decreased brain dopaminergic transporters in HIV-associated dementia patients[J]. Brain, 2004, 127(11): 2452-2458.
[11]  Yu D J, Zeng Y B, Qi Y X, et al. A novel electrochemical sensor for determination of dopamine based on AuNPs@SiO2 core-shell imprinted composite[J]. Biosensors & Bioelectronics, 2012, 38(1): 270-277.
[12]  Bai Z Y, Zhou C, Xu H B, et al. Polyoxometalates-doped Au nanoparticles and reduced graphene oxide: A new material for the detection of uric acid in urine[J]. Sensors & Actuators B-Chemical, 2017, 243: 361-371.
[13]  Ali J, Farrokhzad Mohammadi Z. Synthesis, characterization, electrochemical behavior and electrocatalytical properties towards nitrate and iodate by alcohol solvated Keggin-type polyoxometalate: The effects of weak intermolecular interactions and solvent on electrocatalytical activity[J]. Journal of Molecular Liquids, 2017, 242: 993-1001.
[14]  Li Y G, Lu Y, Chen W, et al. Polyoxometalate-based metal-organic frameworks assembled under the ionothermal conditions[J]. Crystal Growth & Design, 2011, 11(2): 459-465.
[15]  Liu H Y, Wu H, Yang J, et al. Solvothermal assembly of a series of organic-inorganic hybrid materials constructed from Keggin polyoxometalate clusters and copper(I)-organic frameworks[J]. Crystal Growth & Design, 2011, 11(5): 1786-1797.
[16]  Wang X L, Li N, Tian A X, et al. Unprecedented application of flexible bis(pyridyl-tetrazole) ligands to construct helix/loop subunits to modify polyoxometalate anions[J]. Inorganic Chemistry, 2014, 53(14): 7118-7129.
[17]  Raoof J B, Ojani R, Rashid-Nadimi S. Voltammetric determination of ascorbic acid and dopamine in the same sample at the surface of a carbon paste electrode modified with polypyrrole/ferrocyanide films[J]. Electrochimica Acta, 2005, 50(24): 4694-4698.
[18]  Pandey P C, Upadhyay S, Tiwari I, et al. A novel ferrocene encapsulated palladium-linked ormosil-based electrocatalytic dopamine biosensor[J]. Sensors & Actuators B-Chemical, 2001, 75(1/2): 48-55.
[19]  Zhang Y(张英), Ren W(任旺), Li M J(李敏娇). Simultaneous detection of ascorbic acid (AA), dopamine (DA), and uric acid (UA) at CA/GC electrode[J]. Journal of Electrochemistry(电化学), 2012, 18(1): 79-83.
[20]  Meissam N, Mozhgan K M, Reza A, et al. Simultaneous and sensitive determination of a quaternary mixture of AA, DA, UA and Trp using a modified GCE by iron ion-doped natrolite zeolite-multiwall carbon nanotube[J]. Biosensors & Bioelectronics, 2011, 28(1): 56-63.
[21]  Li X Y, Lu X J, Kan X W. 3D electrochemical sensor based on poly(hydroquinone)/gold nanoparticles/nickel foam for dopamine sensitive detection[J]. Journal of Electroanalytical Chemistry, 2017, 799: 451-458.
[22]  Gu H, Varner E L, Groskreutz S R, et al. In vivo monitoring of dopamine by microdialysis with 1 min temporal resolution using online capillary liquid chromatography with electrochemical detection[J]. Analytical Chemistry, 2015, 87(12): 6088-6094.
[23]  Zhou Y P, Yan H L, Xie Q J, et al. Simultaneous analysis of dopamine and homovanillic acid by high-performance liquid chromatography with wall-jet/thin-layer electrochemical detection[J]. Analyst, 2013, 138(23): 7246-7253.
[24]  Asim O, Alper T C, Hilal G, et al. A new Keggin-type polyoxometalate catalyst for degradation of aqueous organic contaminants[J]. Journal of Molecular Structure, 2017, 1134(15): 78-84.
[25]  Chen L, Tian L, Liu L, et al. Preparation and assay performance of supramolecule of cyclophane-complexed polyoxometalates supported on the gold surface[J]. Sensors and Actuators B-Chemical, 2005, 110(2): 271-278.
[26]  Niu X L, Yang W, Guo H, et al. Highly sensitive and selective dopamine biosensor based on 3,4,9,10-perylene tetracarboxylic acid functionalized graphene sheets/multi-wall carbon nanotubes/ionic liquid composite film modified electrode[J]. Biosensors & Bioelectronics, 2013, 41(5): 225-231.
[27]  Pruneau S, Biris A R, Pogacean F, et al. The influence of uric and ascorbic acid on the electrochemical detection of dopamine using graphene-modified electrodes[J]. Electrochimica Acta, 2015, 154(37): 197-204.
[28]  Sun D W(孙德武), Lin X F(林险峰), Li H D(李恒达). Hydrothermal synthesis and characterization of a new type of supermolecular compound [C10H9N2][C10H10N2]-[PW12O40]·2H2O crystals[J]. Journal of Jilin Normal University(Natural Science Edition)(吉林师范大学学报(自然科学版)), 2006, 27(4): 13-14.
[29]  Lydon C, Busche C, Miras H N, et al. Nanoscale growth of molecular oxides: Assembly of a {V6} double cubane between two lacunary {P2W15} polyoxometalates[J]. Angewandte Chemie-International Edition, 2012, 51(9): 2115-2118.


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