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Mild Cognitive Impairment in Parkinson Disease: A Neuropsychological Study of 25 Patients

DOI: 10.4236/wjns.2018.84037, PP. 470-479

Keywords: MCI, PD, Neuropsychological Study, Executive Functions, Episodic Memory, Visuospatial Capacities

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Parkinson’s disease (PD) is associated with an increased incidence of cognitive impairment and dementia. Population-based cohort of 25 patients with incident PD underwent a large neuropsychological battery. Executive functions were the most affected cognitive domain including particularly initiation, mental flexibility and inhibition. Episodic memory and visuo-spatial functions were less affected. We found that 92% of patients were classified as having Mild Cognitive Impairment (MCI); most of them experienced PD-MCI Single-Domain (17 patients) with disturbances on executive functions. Less frequently, we identified a group of patients with multiple-domain PD-MCI demonstrating deficits on executive functions as well as on episodic memory and/or visuospatial capacities.


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