Interstitial lung diseases (ILD’s) are a group of heterogenous chronic, ferociously progressive lung diseases. The aetiology of the aforementioned diseases is not always recognisable. The diagnosis of these dismal diseases is a vivid challenge for the physicians. Through the intervening years different diagnostic algorithms have been implemented towards more accurate outcome. Different types of ILD’s demand diverse diagnostic approaches. In the latest years a novel diagnostic mini invasive approach seems to gain continuously terrain towards the diagnosis of ILD’s. Transbronchial cryobiopsy may be the Holy Grail in the diagnosis of these diseases or a misleading diagnostic tool in this challenging field.
References
[1]
Nalysnyk, L., et al. (2012) Incidence and Prevalence of Idiopathic Pulmonary Fibrosis: Review of the Literature. European Respiratory Review, 21, 355-361. https://doi.org/10.1183/09059180.00002512
[2]
Raghu, G., et al. (2018) Diagnosis of Idiopathic Pulmonary Fibrosis. An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline. American Journal of Respiratory and Critical Care Medicine, 198, e44-e68. https://doi.org/10.1164/rccm.201807-1255ST
[3]
Hetzel, J., et al. (2018) Transbronchial Cryobiopsies for the Diagnosis of Diffuse Parenchymal Lung Diseases: Expert Statement from the Cryobiopsy Working Group on Safety and Utility and a Call for Standardization of the Procedure. Respiration, 9, 188-200. https://doi.org/10.1159/000484055
[4]
Lentz, R.J., Taylor, T.M., Kropski, J.A., Sandler, K.L., Johnson, J.E., Blackwell, T.S., Maldonado, F. and Rickman, O.B. (2018) Utility of Flexible Bronchoscopic Cryobiopsy for Diagnosis of Diffuse Parenchymal Lung Diseases. The Journal of Bronchology and Interventional Pulmonology, 25, 88-96.
[5]
Lentz, R.J., et al. (2017) Transbronchial Cryobiopsy for Diffuse Parenchymal Lung Disease: A State-of-the-Art Review of Procedural Techniques, Current Evidence, and Future Challenges. Journal of Thoracic Disease, 9, 2186-2203. https://doi.org/10.21037/jtd.2017.06.96
[6]
Kropski, J.A., et al. (2013) Bronchoscopic Cryobiopsy for the Diagnosis of Diffuse Parenchymal Lung Disease. PLoS One, 8, e78674. https://doi.org/10.1371/journal.pone.0078674
[7]
Bango-álvarez, A., et al. (2017) Transbronchial Cryobiopsy in Interstitial Lung Disease: Experience in 106 Cases—How to Do It. ERJ Open Research, 3, 00148-2016. https://doi.org/10.1183/23120541.00148-2016
[8]
Sriprasart, T., Aragaki, A., Baughman, R., Wikenheiser-Brokamp, K., Khanna, G., Tanase, D., Kirschner, M. and Benzaquen, S. (2017) A Single US Center Experience of Transbronchial Lung Cryobiopsy for Diagnosing Interstitial Lung Disease with a 2-Scope Technique. Journal of Bronchology and Interventional Pulmonology, 24, 131-135. https://doi.org/10.1097/LBR.0000000000000366
[9]
Babiak, A., Hetzel, J., Krishna, G., Fritz, P., Moeller, P., Balli, T. and Hetzel, M. (2009) Transbronchial Cryobiopsy: A New Tool for Lung Biopsies. Respiration, 78, 203-208. https://doi.org/10.1159/000203987
[10]
Griff, S., et al. (2011) Morphometrical Analysis of Transbronchial Cryobiopsies. Diagnostic Pathology, 6, 53. https://doi.org/10.1186/1746-1596-6-53
[11]
Pajares, V., et al. (2014) Diagnostic Yield of Transbronchial Cryobiopsy in Interstitial Lung Disease: A Randomized Trial. Respirology, 19, 900-906. ttps://doi.org/10.1111/resp.12322
[12]
Ramaswamy, A., Homer, R., Killam, J., Pisani, M.A., Murphy, T.E., Araujo, K. and Puchalski, J. (2016) Comparison of Transbronchial and Cryobiopsies in Evaluation of Diffuse Parenchymal Lung Disease. Journal of Bronchology & Interventional Pulmonology, 23, 14-21. https://doi.org/10.1097/LBR.0000000000000246
[13]
Ravaglia, C., Bonifazi, M., Wells, A.U., Tomassetti, S., Gurioli, C., Piciucchi, S., Dubini, A., Tantalocco, P., Sanna, S., Negri, E., Tramacere, I., Ventura, V.A., Cavazza, A., Rossi, A., Chilosi, M., La Vecchia, C., Gasparini, S. and Poletti, V. (2016) Safety and Diagnostic Yield of Transbronchial Lung Cryobiopsy in Diffuse Parenchymal Lung Diseases: A Comparative Study versus Video-Assisted Thoracoscopic Lung Biopsy and a Systematic Review of the Literature. Respiration, 91, 215-227. https://doi.org/10.1159/000444089