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International Journal of Organic Chemistry 2018

Metals Complexes Formed with Oleanolic Acid

DOI: 10.4236/ijoc.2018.81011, PP. 160-169

Nilton C. Ribeiro, Antonio J. Demuner, Marcelo H. dos Santos, Célia R. A. Maltha, Elson A. de Alvarenga, Slavko Komarnytsky

Keywords: Oleanolic Acid, Complex, PCR

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Abstract:

The oleanolic acid possesses diverse pharmacological properties, it is considered as a good starting material for creating new compounds. The oleanolic acid isolated of Plumeria obtusa leaves was used as raw material to obtained calcium, magnesium, zinc, nickel and copper complexes. The structures of complexes were confirmed by HRMS, ¹H NMR, and ¹³C NMR. Five new compounds were synthesized to promote increased biological activity of oleanolic acid and PCR assays for the different type of cancer.

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