amines are frequently used in cardioology. The aim of our work was to evaluate
the practical modalities of use of amines in the cardiology department of University Hospital Yalgado Ouédraogo. Patients
and Methods: We conducted a prospective observational study for 6 months, from
01 June to 31 November 2013, including all patients treated with vasopressive
amines. We were interested in the different clinical pictures, the indications,
the choice of amines, and the practical application of the treatment. Results:
Fifty patients were included in the study; the mean age was 58 ± 17.6. The sex
ratio was 0.85. Hypertensive heart disease was the underlying cardiac disease
in 34% of cases. A known chronic heart failure was observed in 62% of cases.
Clinical admission tables were dominated by overall heart failure (74%). Vascular collapse (38%) and shock (36%) were the
main indications of treatment. Severe alterations in left ventricular systolic
function were found in 74% of cases. Dobutamine was the amine of choice (90%).
The average time to start treatment was 96.32 minutes (range 15-660
time to relay between syringes was more than ten minutes in 72% of the cases,
and the nurses’ unavailability was the main cause. Monitoring was manual in
almost all cases. The average duration of treatment was 6.64 days.
Treatment-related incidents were observed in 26% of cases. The intra-hospital
mortality of patients with amines was 48%. Conclusion: The indications of vasopressive
amines in the cardiology department are close to the international
recommendations. But this treatment suffers in its practical application. The
duration of treatment remains excessive but is explained by the lack of
Teerlink, J.R., Metra, M., Zaca, V., et al. (2009) Agents with Inotropic Properties for the Management of Acute Heart Failure Syndromes. Traditional Agents and Beyond. Heart Failure Reviews, 14, 243-253.
ACCF/AHA Guidelines for the Diagnosis and Management of Heart Failure in Adults: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines: Developed in Collaboration with the International Society for Heart and Lung Transplantation. Circulation, 119, 1977-2016
ESC Guidelines for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2008: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of the European Society of Cardiology. Developed in Collaboration with the Heart Failure Association of the ESC (HFA) and Endorsed by the European Society of Intensive Care Medicine (ESICM) (2008). European Journal of Heart Failure, 10, 933-989.
Tacon, C.L., Mc Caffrey, J. and Delaney, A. (2012) Dobutamine for Patients with Severe Heart Failure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Intensive Care Medicine, 38, 359-367.
Gheorghiade, M., Vaduganathan, M., Ambrosy, A., et al. (2013) Current Management and Future Directions for the Treatment of Patients Hospitalized for Heart Failure with Low Blood Pressure. Heart Failure Reviews, 18, 107-122.