Although very rare, the literature
describes cases of Hashimoto encephalopathy attesting to its occurrence.
Affected patients present with seizures, stroke-like episodes, transient focal
and global neurological deficits, and a variety of neuropsychiatric disturbance
from dementia to hallucinations and psychosis. The encephalopathy evolves with
concomitantly elevated anti-thyroid peroxidase antibodies, independent from
hormonal thyroid function setting it apart from thyrotoxicosis and myxedema. A
new patient reported with Hashimoto’s encephalopathy, in whom neurocognitive
impairment and stroke-like onset of hemiparesis and hemiparkinsonism correlated
with brain magnetic resonance imaging fused with positron emission tomography.
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