ColdZyme？ Mouth Spray (ColdZyme) is a mouth spray intended to reduce the probability of catching a cold and/or can help shorten the duration of a cold if used at an early stage of the infection, by forming a barrier on the pharyngeal mucous membrane. This study evaluated the preventative effect of ColdZyme on common cold infections in personnel at elderly care facilities, and assessed the level of reduction in corresponding sick leave. The number of sick-leave days for the personnel decreased from an average of 5.2 days to 3.7 days (29%) when using ColdZyme compared to control period (p = 0.054). 63% of those who had a cold reported the symptoms to be milder than previous colds. Conclusion: Using ColdZyme？ Mouth Spray to apply a barrier to the oropharynx may be an easy and practical way to prevent or reduce infections of the common cold virus and corresponding sick leave in personnel working in elderly care.
References
[1]
Utsumi, M., Makimoto, K., Quroshi, N. and Ashida, N. (2010) Types of Infectious Outbreaks and Their Impact in Elderly Care Facilities: A Review of the Literature. Age and Ageing, 39, 299-305. https://doi.org/10.1093/ageing/afq029
[2]
Smith, P.W., Bennett, G., Bradley, S., Drinka, P., Lautenbach, E., Marx, J., et al. (2008) SHEA/APIC Guideline: Infection Prevention and Control in the Long-Term Care Facility, July 2008. Infection Control and Hospital Epidemiology, 29, 785-814.
https://doi.org/10.1086/592416
[3]
Loeb, M., McGeer, A., McArthur, M., Peeling, R.W., Petric, M. and Simor, A.E. (2000) Surveillance for Outbreaks of Respiratory Tract Infections in Nursing Homes. Canadian Medical Association Journal, 162, 1133-1137.
[4]
Sepkowitz, K.A. (1996) Occupationally Acquired Infections in Health Care Workers. Part I. Annals of Internal Medicine, 125, 826-834.
https://doi.org/10.7326/0003-4819-125-10-199611150-00007
[5]
Vareille, M., Kieninger, E. and Edwards, M.R. (2011) The Airway Epithelium: Soldier in the Fight against Respiratory Viruses. Clinical Microbiology Reviews, 24, 210-229. https://doi.org/10.1128/CMR.00014-10
[6]
Clarsund, M., Fornbacke, M., Uller, L. and Ahlström Emanuelsson, C. (2014) Common Cold Prophylaxis Using ColdZyme Mouth Spray. XXXII Congress of the Nordic Association of Otolaryngology, Copenhagen, 22-24 May 2014.
[7]
Nichol, K.L., Lind, A. and Margolis, K.L. (1995) The Effectiveness of Vaccination against Influenza in Healthy, Working Adults. New England Journal of Medicine, 333, 889-893. https://doi.org/10.1056/NEJM199510053331401
[8]
Feeney, A., North, F., Head, J. and Canner, R. (1998) Socioeconomic and Sex Differentials in Reason for Sickness Absence from the Whitehall II Study. Occupational and Environmental Medicine, 55, 91-98. https://doi.org/10.1136/oem.55.2.91
[9]
Hellgren, J., Cervin, A., Nordling, S., Bergman, A. and Cardell, L.O. (2010) Allergic Rhinitis and the Common Cold-High Cost to Society. Allergy, 65, 776-783.
https://doi.org/10.1111/j.1398-9995.2009.02269.x
