The present study was aimed to observe the effects
of urea ingestion, non-protein nitrogen, on the disorder of nitrogen metabolism
with the L-carnitine contents using the blood, kidney, liver, and femoral
muscle as markers. A total of 8 Japanese white rabbits were used in this experiment. They were fed a basal diet
prepared for the control group and the nitrogen volume proportionated to
one-third of CP 14%, was replaced with urea in the feed of the experimental
group for 7 days. On the final day, the
animals were fasted from the previous evening and sacrificed. Blood was collected
into a test tube at the same time of the sacrifice and their heart, kidney,
liver and femoral muscle were collected. The L-carnitine contents in each
sample and the urea in the blood were determined. The results of the growth
test showed that there was no significant difference. Furthermore, there was no
significant difference in the contents of L-carnitine and urea in each sample. It
was concluded that nitrogen replacement of the diet with urea, in the range of
1/3 of dietary protein, had neither effect on the maintenance of body weight
nor nitrogen balance, including the de
novo synthesis of L-carnitine.
Sukemori, S., Odo, S. and Ikeda, S. (2016) Effects of L-Carnitine Supplementation on Growth Performance and Fatty Acid Proportion in Epididymal Adipose Tissue of Rats Fed Diets Containing Fat from Different Sources. Journal of Veterinary Science and Medical Diagnosis, 5, 1.
Sukemori, S., Odo, S. and Ikeda, S. (2016) Dietary Supplementation with L-Carnitine Induces Equal Utilization of Long-Chain Fatty Acids for Energy Production in Rats Trained with Walking. Journal of Veterinary Science and Medical Diagnosis, 5, 4.
Sukemori, S., Ikeda, S., Kurihara, Y. and Ito, S. (2002) Amino Acid, Mineral and Vitamin Levels in Hydrous Faeces Obtained from Coprophagy-Prevented Rats. Journal of Animal Physiology and Animal Nutrition, 87, 213-220.
Sukemori, S., Kurosawa, A., Ikeda, S. and Kurihara, Y. (2006) Investigation on the Growth of Coprophagy-Prevented Rats with Supplemented Vitamin B12. Journal of Animal Physiology and Animal Nutrition, 90, 402-406. https://doi.org/10.1111/j.1439-0396.2006.00619.x
Goto, M. and Takahashi, N. (1978) Effect of NPN Supplementation on the Protein Contents in Cecum of Rabbits and Nitrogen-Balance under the Coprophagy-Prevented Condition. Bulletin of the Department of Agriculture, Meiji University, 45, 1-6.
Casillas, E.R. and Chaipayungpan, S. (1982) Carnitine Content of Rabbit Epididymal Spermatozoa in Organ Culture. Journal of Reproduction and Fertility, 65, 247-251.
Curto, M., Piccinni, M., Mioletti, S., Bruno, R., Ricciardi, M.P. and Rinaudo, M.T. (1994) Levels of Carnitine and Glycogen in Rabbit Tissues during Development. The International Journal of Biochemistry, 26, 163-169. https://doi.org/10.1016/0020-711X(94)90141-4
Mohammed, M. and Jamala, G.Y. (2013) Performance and Nutrient Digestibility of Rabbit Fed Urea Treated Cowpea Husk. IOSR Journal of Agriculture and Veterinary Science, 5, 34-37. https://doi.org/10.9790/2380-0523437