In order to study the failure characteristics of rocks under coupling effect of ground stress field and seepage field, MTS815 rock mechanics test system combined with plunger pump hydraulic loading device are used to load water pressures on concrete samples containing precast crack. After that, uniaxial cyclic loading and unloading compression failure contrast experiments are conducted with the seepage field and without the seepage field. The results show that: specimens with the seepage field present initial crack at the initial stage of loading, but species without seepage field present initial crack always in plastic zone or close to plastic zone. The failure mode under both conditions is not the same. The failure is caused by surface crack expand under the water pressure effects, and without water pressure it is caused by the internal damage and micro cracks extend. The strength under the two kinds of conditions is equivalent, while the dissipated energy in the process of failure is higher than those without seepage field.