Aim: We report a case of fungal keratitis and Ocular Surface Squalous Neoplasia
(OSSN) occurring in a HIV positive patient. Method: A 32-year-old female patient
presented with a non-healing ulcer, which was diagnosed as fungal keratitis. On
examination her ocular surface also revealed OSSN on the nasal bulbar
conjunctiva. Serological investigations revealed HIV positive status with CD 4
counts of 61 cells/μl. Patient was treated for fungal keratitis with topical
antifungals and also underwent excision biopsy
of OSSN which was reported as conjunctival intraepithelial neoplasia. The ulcer
showed significant response to topical medication only after the commencement
of Anti-Retroviral Therapy (ART). Conclusion: This case emphasizes on
the importance of a thorough ocular examination to rule out associated ocular
conditions and investigations to rule out immunosuppressive status in a
non-healing ulcer.
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