All Title Author
Keywords Abstract


Esophageal Cancer: Epidemiological, Clinical and Histopathological Aspects over a 24-Years Period at Kamenge University Hospital, Bujumbura, Burundi

DOI: 10.4236/ojgas.2016.64014, PP. 106-110

Keywords: Esophageal Cancer, Squamous Cell Carcinoma, Adenocarcinoma, Digestive Cancer

Full-Text   Cite this paper   Add to My Lib

Abstract:

Aim: There were no data about esophageal cancer in Burundi. The aim of the study was to highlight the epidemiological, clinical and histopathological aspects of the esophageal cancer. Method: A retrospective study over a 24-years period (from January 1988 to December 2011) was carried out at Kamenge university hospital, including patients with esophageal cancer. The cases were selected on basis of the histological evidence of the cancer. Results: A total of 34 cases were retrieved and included for analysis. Among them, 24 patients (70.5%) were males. The esophageal cancer constituted 8.6% of digestive cancers over the period of the study. The average age was 50.9 years. It was revealed by dysphagia in 32 patients (94.1%) and was concomitantly metastatic in 12 patients. The squamous cell carcinoma was 30 cases (88.2%). 27 patients underwent a curative resection, but the outcome and prognosis were poor. In-hospital mortality and morbidity rates were respectively 8.8% and 17.7%. Conclusion: The present study showed evidence that the esophageal cancer in our country had the same characteristics and distribution as well as in developing countries. It had a poor prognosis and efforts had to be done in the early cancer detection.

References

[1]  Hongo, M., Nagasaki, Y. and Shoji, T. (2009) Epidemiology of Esophageal Cancer: Orient to Occident. Effects of Chronology, Geography and Ethnicity. Journal of Gastroenterology and Hepatology, 24, 729-735.
http://dx.doi.org/10.1111/j.1440-1746.2009.05824.x
[2]  Zheng, S., Vuitton, L., Sheyhidin, L., Vuitton, D.A., Zhang, Y. and Lu, X. (2010) Northwestern China: A Place to Learn More on Oesophageal Cancer. Part One: Behavioural and Environmental Risk Factors. European Journal of Gastroenterology & Hepatology, 22, 917-925.
http://dx.doi.org/10.1097/MEG.0b013e3283313d8b
[3]  Yang, C.S. (1980) Research on Esophageal Cancer in China: A Review. Cancer Research, 40, 2633-2644.
[4]  Maiga, Y.M., Diallo, G., Dembele, M., Ndiaye, M., Ongoiba, N., Sanogo, Z., Yena, S. and Traoré, H.A. (2002) Cancer de l’aesophage: Aspects épidémiologiques, cliniques et pronostiques. Acta Endoscopica, 32, 455-459.
http://dx.doi.org/10.1007/BF03020579
[5]  Bagny, A., Bouglouga, O., Djibril, M.A., M’ba, K.B., Kaaga, L., Lawson A.L., Amégbor, K., Darré, T. and Redah, D. (2012) Cancer de l’oesophage : Aspect épidémiologique, clinique et histologique au CHU Campus de Lomé (Togo). Journal Africain d’Hépato-Gastroentérologie, 6, 24-27.
http://dx.doi.org/10.1007/s12157-011-0339-2
[6]  Harouna, Y.D., Illo, A., Assoumane, I. and Onouha, C. (2008) Cancers de l’aesophage au Niger: Aspects épidémiologiques, cliniques à propos de 36 cas. Médecine d’Afrique Noire, 55, 235-239.
[7]  Ntagirabiri, R., Mumana, A., Baransaka, E., Niyonzima, S. and Ndayishimiye, H. (2013) Gastro-Esophageal Reflux Disease among People Consulting in Bujumbura. J. Afr. Hépatol. Gastroentérol, 7, 204-207.
http://dx.doi.org/10.1007/s12157-013-0496-6
[8]  Ntagirabiri, R., Niyonzima, S., Mumana, A.L. and Ndabaneze, E. (2013) Gastro-Esophageal Reflux Disease in African Young Adult: Case of Burundian University Students. Journal Africain d’Hépato-Gastroentérologie, 7, 192-195.
http://dx.doi.org/10.1007/s12157-013-0489-5
[9]  Ndahindwa, V., Ngendahayo, L. and Vyankandondera, J. (2012) Aspects épidémiologiques et anatomopathologiques des cancers dans les centres hospitaliers universitaires (chu) du rwanda. Revue Médicale Rwandaise, 69, 40-49.
[10]  Kadende, P., Engels, D., Ndoricimpa, J., Ndabaneze, E., Habonimana, D., Marerwa, G., Bigirimana, V., Bazira, L. and Aubry, P. (1990) Les cancers digestifs au Burundi: Premiers résultats d’une enquête menée à Bujumbura. Médecine d’Afrique Noire, 37, 552-562.
[11]  Dia, D., Bassène, M.L., Ndiaye-Ba, N., Halim, A., Diallo, S., Fall, S., Diouf, M.F., Mbengue, M. and Diouf, M.L. (2011) Endoscopic Features of Esophageal Cancer in Dakar, Senegal: Study of 76 Observations. Médecine Tropicale, 71, 286-288.
[12]  Sawadogo, A., Ilboudo, P.D., Durand, G., Peghini, M., Branquet, D., Sawadogo, A.B. and Ouedraogo, I. (2000) Epidémiologie des cancers du tube digestif au Burkina Faso: Apport de 8000 endoscopies effectuées au centre hospitalier Sanou sourou (CHSS) de Bobo dioulasso. Médecine d’Afrique Noire, 7, 342-345.
[13]  Pindiga, H.U., Akang, E.E., Thomas, J.O. and Aghadiuno, P.U. (1997) Carcinoma of the Esophagus in Ibadan. East African Medical Journal, 7, 307-310.
[14]  Kelsen, D.P., Ginsberg, R., Pajak, T.F., Sheahan, D.G., Gunderson, L., Mortimmer, J., Estes, N., Haller, D.G., Ajani, J., Kocha, W., Minsky, B.D. and Roth, J.A. (1998) Chemotherapy Followed by Surgery versus Surgery Alone for Localized Esophageal Cancer. The New England Journal of Medicine, 339, 1979-1984.
http://dx.doi.org/10.1056/NEJM199812313392704
[15]  Ruol, A., Castoro, C., Portale, G., Cavallin, F., Sileni, V.C., Cagol, M., Alfieri, R., Corti, L., Boso, C., Zaninotto, G., Peracchia, A. and Ancona, E. (2009) Trends in Management and Prognosis for Esophageal Cancer Surgery. Archives of Surgery, 144, 247-254.
http://dx.doi.org/10.1001/archsurg.2008.574

Full-Text

comments powered by Disqus