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Calcifying Epithelial Odontogenic Tumor

DOI: 10.1155/2013/725380

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The calcifying epithelial odontogenic tumor (CEOT) is a rare benign epithelial odontogenic neoplasm of slow growth that is locally aggressive and tends to invade bone and adjacent soft tissue. Here is reported the case of a 21-year-old female patient with a CEOT in the left mandibular posterior region. The computerized tomography in coronal plane revealed a hypodense lesion in the posterior region of the left mandibular body with hyperdense areas inside and was associated with element 37. An incisional biopsy of the lesion was performed and the histopathological analysis revealed the presence of layers of epithelial odontogenic cells that formed prominent intercellular bridges. A large quantity of extracellular, eosinophilic, and amyloid-like material and an occasional formation of concentric calcifications (Liesegang rings) were also found. The histopathological diagnosis was a Pindborg tumor. Resection of the tumor with a safety margin was performed and after 6 months of follow-up there has been no sign of recurrence of the lesion. 1. Introduction The calcifying epithelial odontogenic tumor (CEOT) or Pindborg tumor is a rare benign epithelial odontogenic neoplasm [1, 2], with approximately 200 reported cases in the literature [3]. In general it occurs as a slow-growing tumor [4], associated with an impacted tooth in the posterior mandibular region [5, 6]. This occurs predominantly between the fourth and fifth decades of life, with no preference of gender [2–4]. Radiographically, CEOT is characterized by a uni- or multilocular lesion that often shows a mixed radiolucent-radiopaque pattern [6]. Treatment consists in the surgical removal of the lesion, with recurrence in 14% of cases [5]. The prognosis is considered good [6]. 2. Case Report A 21-year-old black female patient sought treatment at the Oral and Maxillofacial Trauma Surgery Unit, with swelling in the mandibular left posterior region. While performing the intraoral physical exam an asymptomatic hardened exophytic nodule was found in region 37 (Figure 1). Figure 1: Intraoral aspect of the lesion, characterized by a hardened nodular and exophytic mass in the mandibular body, on the left side. The patient reported a clinical evolution of only five months of the lesion. A radiographic exam revealed a diffuse radiolucent, unilocular lesion, associated with region 37, yet including the distal root of region 36 up to the crown of region 38 (Figure 2). Using a computerized tomography in coronal section, it was possible to observe that it was a question of a local hypodense lesion in the mandibular

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