All Title Author
Keywords Abstract


Lymphoma of the Urinary Bladder

DOI: 10.1155/2014/327917

Full-Text   Cite this paper   Add to My Lib

Abstract:

Background. Lymphoma of the urinary bladder (LUB) is rare. Aims. To review the literature on LUB. Methods. Various internet databases were used. Results. LUB can be either primary or secondary. The tumour has female predominance; most cases occur in middle-age women. Secondary LUB occurs in 10% to 25% of leukemias/lymphomas and in advanced-stage systemic lymphoma. Less than 100 cases have been reported. MALT typically affects adults older than 60 years; 75% are female. Diffuse large B-cell lymphoma is also common and may arise from transformation of MALT. LUB presents with haematuria, dysuria, urinary frequency, nocturia, and abdominal or back pain. Macroscopic examination of LUBs show large discrete tumours centred in the dome or lateral walls of the bladder. Positive staining of LUB varies by the subtype of lymphoma; B-cell lymphomas are CD20 positive. MALT lymphoma is positively stained for CD20, CD19, and FMC7 and negatively stained for CD5, CD10, and CD11c. LUB stains negatively with Pan-keratin, vimentin, CK20, and CK7. MALT lymphoma exhibits t(11; 18)(q21: 21). Radiotherapy is an effective treatment for the MALT type of LUB with no recurrence. Conclusions. LUB is diagnosed by its characteristic morphology and immunohistochemical characteristics. Radiotherapy is a useful treatment. 1. Introduction Lymphoma of the urinary bladder is an uncommon lesion; and its diagnostic features may not be well known by the unaccustomed practitioner. The ensuing document contains a review of the literature on lymphoma of the urinary bladder. 2. Methods The key words used for the search were Lymphoma of bladder; lymphoma of urinary bladder; vesical lymphoma. Documentations from 46 sources were found which had discussed various aspects relevant to lymphoma of the urinary bladder and information from these 46 sources were used to write the literature review. 3. Literature Review 3.1. Overview Definition. Lymphoma of the urinary bladder can be either (a) primary lymphoma of the urinary bladder and this is a rare lymphoma originating in the urinary bladder with no known lymphoma elsewhere or (b) secondary lymphoma of the urinary bladder and this is much more common, and this secondary lymphoma is associated with a primary lymphoma originating in an extra vesical site [1]. Epidemiology. Lymphomas of the urinary bladder have a female predominance, and most cases of lymphoma of the urinary bladder occur in middle-age women [1]. Secondary involvement of the urinary bladder occurs in 10% to 25% of leukemias/lymphomas and they occur in advanced-stage systemic lymphoma [1].

References

[1]  G. Levy, “Bladder Other tumors Lymphoma (primary),” PathologyOutlines.com 2011, http://www.pathologyoutlines.com/topic/bladderlymphoma.html.
[2]  A. W. Bates, A. J. Norton, and S. I. Baithun, “Malignant lymphoma of the urinary bladder: a clinicopathological study of 11 cases,” Journal of Clinical Pathology, vol. 53, no. 6, pp. 458–461, 2000.
[3]  C. L. Kempton, P. J. Kurtin, D. J. Inwards, P. Wollan, and D. G. Bostwick, “Malignant lymphoma of the bladder: evidence from 36 cases that low- grade lymphoma of the malt-type is the most common primary bladder lymphoma,” American Journal of Surgical Pathology, vol. 21, no. 11, pp. 1324–1333, 1997.
[4]  J. Al-Maghrabi, S. Kamel-Reid, M. Jewett, M. Gospodarowicz, W. Wells, and D. Banerjee, “Primary low-grade B-cell lymphoma of mucosa-associated lymphoid tissue type arising in the urinary bladder: report of 4 cases with molecular genetic analysis,” Archives of Pathology and Laboratory Medicine, vol. 125, no. 3, pp. 332–336, 2001.
[5]  L. R. Zukerberg, N. L. Harris, and R. H. Young, “Carcinomas of the urinary bladder simulating malignant lymphoma: a report of five cases,” American Journal of Surgical Pathology, vol. 15, no. 6, pp. 569–576, 1991.
[6]  D. D. Cohen, C. Lamarre, L. Lamarre, and F. S. Fred Saad, “Primary low-grade B-cell lymphoma of the urinary bladder: case report and literature review,” The Canadian Journal of Urology, vol. 9, no. 6, pp. 1694–1697, 2002.
[7]  G. Sufrin, B. Keogh, R. H. Moore, and G. P. Murphy, “Secondary involvement of the bladder in malignant lymphoma,” Journal of Urology, vol. 118, no. 2, pp. 251–253, 1977.
[8]  H. Kuhara, Z. Tamura, T. Suchi, R. Hattori, and T. Kinukawa, “Primary malignant lymphoma of the urinary bladder. A case report,” Acta Pathologica Japonica, vol. 40, no. 10, pp. 764–769, 1990.
[9]  M. S?nmezer, A. Ensari, Y. üstün, M. Güng?r, and F. Orta?, “Primary lymphoma of the urinary bladder presenting as a large pelvic mass,” Journal of the Pakistan Medical Association, vol. 52, no. 5, pp. 228–230, 2002.
[10]  M. Ohsawa, K. Aozasa, K. Horiuchi, and A. Kanamaru, “Malignant lymphoma of bladder: report of three cases and review of the literature,” Cancer, vol. 72, no. 6, pp. 1969–1974, 1993.
[11]  M. Raderer, S. W?hrer, B. Streubel et al., “Activity of rituximab plus cyclophosphamide, doxorubicin/mitoxantrone, vincristine and prednisone in patients with relapsed MALT lymphoma,” Oncology, vol. 70, no. 6, pp. 411–417, 2006.
[12]  Y. Terasaki, H. Okumura, Y. Ishiura et al., “Primary mucosa-associated lymphoid tissue lymphoma of the urinary bladder successfully treated by radiotherapy and rituximab,” Rinsho Ketsueki, vol. 49, no. 1, pp. 30–34, 2008.
[13]  Y. Takahara, H. Kawashima, Y.-S. Han et al., “Primary mucosa-associated lymphoid tissue (MALT) lymphoma of the urinary bladder,” Hinyokika Kiyo, vol. 51, no. 1, pp. 45–48, 2005.
[14]  Y. Kakuta, T. Katoh, J. Saitoh, K. Yazawa, M. Hosomi, and K. Itoh, “A case of primary mucosa-associated lymphoid tissue lymphoma of the bladder regressed after rituximab in combination with CHOP chemotherapy,” Acta Urologica Japonica, vol. 52, no. 12, pp. 951–954, 2006.
[15]  R. J. Siegel and V. M. Napoli, “Malignant lymphoma of the urinary bladder: a case with signet-ring cells stimulating urachal adenocarcinoma,” Archives of Pathology and Laboratory Medicine, vol. 115, no. 6, pp. 635–637, 1991.
[16]  A. Hayashi, Y. Miyakawa, K. Bokuda et al., “Primary diffuse large B-cell lymphoma of the bladder,” Internal Medicine, vol. 48, no. 16, pp. 1403–1406, 2009.
[17]  N. Z. Abraham Jr., T. J. Maher, and R. E. Hutchison, “Extra-nodal monocytoid B-cell lymphoma of the urinary bladder,” Modern Pathology, vol. 6, no. 2, pp. 145–149, 1993.
[18]  S. Sundaram and K. Zhang, “Epstein-Barr virus positive B-cell lymphoproliferative disorder/ polymorphous B-cell lymphoma of the urinary bladder: a case report with review of literature,” Indian Journal of Urology, vol. 25, no. 1, pp. 129–131, 2009.
[19]  K. C. Oh and D. Y. Zang, “Primary non-Hodgkin's lymphoma of the bladder with bone marrow involvement,” The Korean journal of internal medicine, vol. 18, no. 1, pp. 40–44, 2003.
[20]  L. Wang, Z. Z. Cao, and L. Qi, “Primary T-cell lymphoma of the urinary bladder presenting with haematuria and hydroureteronephrosis,” Journal of International Medical Research, vol. 39, no. 5, pp. 2027–2032, 2011.
[21]  W. A. Mourad, S. Khalil, A. Radwi, A. Peracha, and A. Ezzat, “Primary T-cell lymphoma of the urinary bladder,” American Journal of Surgical Pathology, vol. 22, no. 3, pp. 373–377, 1998.
[22]  K. Ando, Y. Matsuno, Y. Kanai et al., “Primary low-grade lymphoma of mucosa-associated lymphoid tissue of the urinary bladder: a case report with special reference to the use of ancillary diagnostic studies,” Japanese Journal of Clinical Oncology, vol. 29, no. 12, pp. 636–639, 1999.
[23]  R. H. W. Simpson, R. S. Amin, and R. D. Pocock, “Malignant lymphoma of the bladder and female urethra,” International Urogynecology Journal, vol. 5, no. 2, pp. 102–105, 1994.
[24]  E. Mearini, A. Zucchi, E. Costantini, P. Fornetti, E. Tiacci, and L. Mearini, “Primary Burkitt's lymphoma of bladder in patient with aids,” Journal of Urology, vol. 167, no. 3, pp. 1397–1398, 2002.
[25]  I. Tsiriopoulos, G. Lee, A. O'Reilly, R. Smith, and M. Pancharatnam, “Primary splenic marginal zone lymphoma with bladder metastases mimicking interstitial cystitis,” International Urology and Nephrology, vol. 38, no. 3-4, pp. 475–476, 2006.
[26]  T. M. Downs, A. S. Kibel, and W. C. DeWolf, “Primary lymphoma of the bladder: a unique cystoscopic appearance,” Urology, vol. 49, no. 2, pp. 276–278, 1997.
[27]  R. H. W. Simpson, J. E. Bridger, P. P. Anthony, K. A. James, and I. Jury, “Malignant lymphoma of the lower urinary tract. A clinicopathological study with review of the literature,” British Journal of Urology, vol. 65, no. 3, pp. 254–260, 1990.
[28]  P. Isaacson and D. H. Wright, “Malignant lymphoma of mucosa-associated lymphoid tissue. A distinctive type of B-cell lymphoma,” Cancer, vol. 52, no. 8, pp. 1410–1416, 1983.
[29]  M. Mantzarides, D. Papathanassiou, G. Bonardel, M. Soret, E. Gontier, and H. Foehrenbach, “High-grade lymphoma of the bladder visualized on PET,” Clinical Nuclear Medicine, vol. 30, no. 7, pp. 478–480, 2005.
[30]  D. A. Evans and A. T. Moore, “The first case of vesico-vaginal fistula in a patient with primary lymphoma of the bladder—a case report,” Journal of Medical Case Reports, vol. 1, article 105, 2007.
[31]  K. Arda, G. ?zdemir, Z. Güne?, and H. ?zdemir, “Primary malignant lymphoma of the bladder. A case report and review of the literature,” International Urology and Nephrology, vol. 29, no. 3, pp. 319–322, 1997.
[32]  M. J. F. Ace?ero, C. M. Rodilla, J. L. García-Asenjo, S. C. Menchero, and J. S. Esponera, “Primary malignant lymphoma of the bladder report of 3 cases,” Pathology, Research and Practice, vol. 192, 1996.
[33]  A. JACOBS and T. SYMINGTON, “Primary lymphosarcoma of urinary bladder,” British journal of urology, vol. 25, no. 2, pp. 119–126, 1953.
[34]  J. A. Diaz-Peromingo, J. T. Tato-Rodriguez, P. M. Pesqueira, S. Molinos-Castro, M. C. Gayol-Fernández, and J. P. Struzik, “Non-Hodgkin’s lymphoma presenting as a primary bladder tumour: a case report,” Journal of Medical Case Reports, vol. 4, pp. 4–114, 2010.
[35]  E. Rijo, O. Bielsa, J. A. Lorente, A. Francés, J. Lloreta, and O. Arango, “Female paraurethral primary Burkitt’s lymphoma, presenting with symptoms of bladder Outlet obstruction, successfully treated with Chemotherapy,” www.bjui.org/ContentFullltem.aspx.
[36]  K. Hatano, M. Sato, Y. Tsujimoto et al., “Primary mucosa-associated lymphoid tissue (MALT) lymphoma of the urinary bladder associated with left renal pelvic carcinoma: a case report,” Acta Urologica Japonica, vol. 53, no. 1, pp. 57–60, 2007.
[37]  P. Dahm and J. E. Gschwend, “Malignant non-urothelial neoplasms of the urinary bladder: a review,” European Urology, vol. 44, no. 6, pp. 672–681, 2003.
[38]  J. A. Ferry, “Burkitt's lymphoma: clinicopathologic features and differential diagnosis,” Oncologist, vol. 11, no. 4, pp. 375–383, 2006.
[39]  A. Shad and I. T. Magrath, “Non-Hodgkin’s lymphoma in children,” in Principles and Practice of Pediatric Oncology, P. A. Pizzo and D. G. Poplack, Eds., pp. 545–548, Lippincott-Raven, Philadelphia, Pa, USA, 3rd edition, 1997.
[40]  W. W. Choi, R. L. Yap, O. Ozer, M. R. Pins, and A. J. Schaeffer, “Lymphoma of the prostate and bladder presenting as acute urinary obstruction,” Journal of Urology, vol. 169, no. 3, pp. 1082–1083, 2003.
[41]  I. Singh, M. Joshi, S. Agarwal, U. R. Singh, and R. Saran, “Extra-nodal small cell lymphocytic lymphoma of prostate: an unusual cause of lower urinary tract symptoms,” Urology, vol. 71, no. 3, pp. 547.e7–549.e7, 2008.
[42]  S. D. Schniederjan and A. O. Osunkoya, “Lymphoid neoplasms of the urinary tract and male genital organs: a clinicopathological study of 40 cases,” Modern Pathology, vol. 22, no. 8, pp. 1057–1065, 2009.
[43]  D. E. Shield and R. M. Weiss, “Leiomyoma of the female urethra,” Journal of Urology, vol. 109, no. 3, pp. 430–431, 1973.
[44]  I. E. Yusim, E. Z. Neulander, I. Eidelberg, L. J. Lismer, and J. Kaneti, “Leiomyoma of the genitourinary tract,” Scandinavian Journal of Urology and Nephrology, vol. 35, no. 4, pp. 295–299, 2001.
[45]  A. Gómez Gallo, J. P. Valdevenito Sepúlveda, and M. San Martín Montes, “Giant lithiasis in a female urethral diverticulum,” European Urology, vol. 51, no. 2, pp. 556–558, 2007.
[46]  D. A. Thomas, J. Cortes, S. O’Brien, et al., “Hyper-CVAD program in Burkitt’s-type adult acute lymphoblastic leukemia,” Journal of Clinical Oncology, vol. 17, no. 8, pp. 2461–2470, 1999.

Full-Text

comments powered by Disqus

Contact Us

service@oalib.com

QQ:3279437679

微信:OALib Journal