| [1] | Monacelli AM, Cushman LA, Kavcic V, Duffy CJ (2003) Spatial disorientation in Alzheimer’s disease: the remembrance of things passed. Neurology 61: 1491–1497.
|
| [2] | Mapstone M, Steffenella TM, Duffy CJ (2003) A visuospatial variant of mild cognitive impairment: getting lost between aging and AD. Neurology 60: 802–808.
|
| [3] | O’Keefe J, Dostrovsky J (1971) The hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving rat. Brain Res 34: 171–175.
|
| [4] | Morris RG, Garrud P, Rawlins JN, O’Keefe J (1982) Place navigation impaired in rats with hippocampal lesions. Nature 297: 681–683.
|
| [5] | Laczo J, Andel R, Vlcek K, Macoska V, Vyhnalek M, et al. (2011) Spatial navigation and APOE in amnestic mild cognitive impairment. Neurodegener Dis 8: 169–177.
|
| [6] | Laczo J, Andel R, Vyhnalek M, Vlcek K, Magerova H, et al. (2010) Human analogue of the morris water maze for testing subjects at risk of Alzheimer’s disease. Neurodegener Dis 7: 148–152.
|
| [7] | Hort J, Laczo J, Vyhnalek M, Bojar M, Bures J, et al. (2007) Spatial navigation deficit in amnestic mild cognitive impairment. Proc Natl Acad Sci USA 104: 4042–4047.
|
| [8] | Laczo J, Vlcek K, Vyhnalek M, Vajnerova O, Ort M, et al. (2009) Spatial navigation testing discriminates two types of amnestic mild cognitive impairment. Behav Brain Res 202: 252–259.
|
| [9] | Czeh B, Stuchlik A, Wesierska M, Cimadevilla JM, Pokorny J, et al. (2001) Effect of neonatal dentate gyrus lesion on allothetic and idiothetic navigation in rats. Neurobiol Learn Mem 75: 190–213.
|
| [10] | Feigenbaum JD, Morris RG (2004) Allocentric versus egocentric spatial memory after unilateral temporal lobectomy in humans. Neuropsychology 18: 462–472.
|
| [11] | Grothe M, Heinsen H, Teipel SJ (2012) Atrophy of the cholinergic Basal forebrain over the adult age range and in early stages of Alzheimer’s disease. Biol Psychiatry 71: 805–813.
|
| [12] | Grothe M, Zaborszky L, Atienza M, Gil-Neciga E, Rodriguez-Romero R, et al. (2010) Reduction of basal forebrain cholinergic system parallels cognitive impairment in patients at high risk of developing Alzheimer’s disease. Cereb Cortex 20: 1685–1695.
|
| [13] | Muth K, Schonmeyer R, Matura S, Haenschel C, Schroder J, et al. (2010) Mild cognitive impairment in the elderly is associated with volume loss of the cholinergic basal forebrain region. Biol Psychiatry 67: 588–591.
|
| [14] | Hall JR, Harvey MB (2008) Behavioral regulation: factor analysis and application of the Behavioral Dyscontrol Scale in dementia and mild cognitive impairment. Int J Geriatr Psychiatry 23: 314–318.
|
| [15] | Gorny JH, Gorny B, Wallace DG, Whishaw IQ (2002) Fimbria-fornix lesions disrupt the dead reckoning (homing) component of exploratory behavior in mice. Learn Mem 9: 387–394.
|
| [16] | Martin MM, Horn KL, Kusman KJ, Wallace DG (2007) Medial septum lesions disrupt exploratory trip organization: evidence for septohippocampal involvement in dead reckoning. Physiol Behav 90: 412–424.
|
| [17] | Henny P, Jones BE (2008) Projections from basal forebrain to prefrontal cortex comprise cholinergic, GABAergic and glutamatergic inputs to pyramidal cells or interneurons. Eur J Neurosci 27: 654–670.
|
| [18] | Blokland A (1995) Acetylcholine: a neurotransmitter for learning and memory? Brain Res Brain Res Rev 21: 285–300.
|
| [19] | Hasselmo ME (2006) The role of acetylcholine in learning and memory. Curr Opin Neurobiol 16: 710–715.
|
| [20] | Perry E, Walker M, Grace J, Perry R (1999) Acetylcholine in mind: a neurotransmitter correlate of consciousness? Trends Neurosci 22: 273–280.
|
| [21] | Schliebs R, Arendt T (2006) The significance of the cholinergic system in the brain during aging and in Alzheimer’s disease. J Neural Transm 113: 1625–1644.
|
| [22] | Mesulam M (2004) The cholinergic lesion of Alzheimer’s disease: pivotal factor or side show? Learn Mem 11: 43–49.
|
| [23] | Perry EK, Tomlinson BE, Blessed G, Perry RH, Cross AJ, et al. (1981) Noradrenergic and cholinergic systems in senile dementia of Alzheimer type. Lancet 2: 149.
|
| [24] | Craig LA, Hong NS, McDonald RJ (2011) Revisiting the cholinergic hypothesis in the development of Alzheimer’s disease. Neurosci Biobehav Rev 35: 1397–1409.
|
| [25] | Pinto T, Lanctot KL, Herrmann N (2011) Revisiting the cholinergic hypothesis of behavioral and psychological symptoms in dementia of the Alzheimer’s type. Ageing Res Rev 10: 404–412.
|
| [26] | Franklin KJB, Paxinos G (2007) The Mouse Brain in Stereotaxic Coordinates Third Edition. San Diego: Academic Press.
|
| [27] | Cimadevilla JM, Kaminsky Y, Fenton A, Bures J (2000) Passive and active place avoidance as a tool of spatial memory research in rats. J Neurosci Methods 102: 155–164.
|
| [28] | Berger-Sweeney J, Stearns NA, Murg SL, Floerke-Nashner LR, Lappi DA, et al. (2001) Selective immunolesions of cholinergic neurons in mice: effects on neuroanatomy, neurochemistry, and behavior. J Neurosci 21: 8164–8173.
|
| [29] | Hunter CL, Quintero EM, Gilstrap L, Bhat NR, Granholm AC (2004) Minocycline protects basal forebrain cholinergic neurons from mu p75-saporin immunotoxic lesioning. Eur J Neurosci 19: 3305–3316.
|
| [30] | Moreau PH, Cosquer B, Jeltsch H, Cassel JC, Mathis C (2008) Neuroanatomical and behavioral effects of a novel version of the cholinergic immunotoxin mu p75-saporin in mice. Hippocampus 18: 610–622.
|
| [31] | Nag N, Baxter MG, Berger-Sweeney JE (2009) Efficacy of a murine-p75-saporin immunotoxin for selective lesions of basal forebrain cholinergic neurons in mice. Neurosci Lett 452: 247–251.
|
| [32] | Gallistel CR (1990) The Organisation of Learning. Cambridge MA: MIT Press.
|
| [33] | Whishaw IQ, Hines DJ, Wallace DG (2001) Dead reckoning (path integration) requires the hippocampal formation: evidence from spontaneous exploration and spatial learning tasks in light (allothetic) and dark (idiothetic) tests. Behav Brain Res 127: 49–69.
|
| [34] | Lee MG, Chrobak JJ, Sik A, Wiley RG, Buzsaki G (1994) Hippocampal theta activity following selective lesion of the septal cholinergic system. Neuroscience 62: 1033–1047.
|
| [35] | Vanderwolf CH (1969) Hippocampal electrical activity and voluntary movement in the rat. Electroencephalogr Clin Neurophysiol 26: 407–418.
|
| [36] | Vanderwolf CH, Kramis R, Robinson TE (1977) Hippocampal electrical activity during waking behaviour and sleep: analyses using centrally acting drugs. CIBA Found Symp: 199–226.
|
| [37] | Tai SK, Ma J, Ossenkopp KP, Leung LS (2012) Activation of immobility-related hippocampal theta by cholinergic septohippocampal neurons during vestibular stimulation. Hippocampus. 22: 914–925.
|
| [38] | Foster TC, Castro CA, McNaughton BL (1989) Spatial selectivity of rat hippocampal neurons: dependence on preparedness for movement. Science 244: 1580–1582.
|
| [39] | Taube JS (1998) Head direction cells and the neurophysiological basis for a sense of direction. Prog Neurobiol 55: 225–256.
|
| [40] | Yoder RM, Pang KC (2005) Involvement of GABAergic and cholinergic medial septal neurons in hippocampal theta rhythm. Hippocampus 15: 381–392.
|
| [41] | Nordberg A (2001) Nicotinic receptor abnormalities of Alzheimer’s disease: therapeutic implications. Biol Psychiatry 49: 200–210.
|
| [42] | Levey AI (1996) Muscarinic acetylcholine receptor expression in memory circuits: implications for treatment of Alzheimer disease. Proc Natl Acad Sci USA 93: 13541–13546.
|
