Multifocal visual evoked potentials in amblyopia due to anisometropia

MM Moschos, I Margetis, S Tsapakis, G Panagakis, IK Chatzistephanou, E IliakisDepartment of Ophthalmology, University of Athens, GreecePurpose: To investigate multifocal visual evoked potentials (mfVEP) of the amblyopic and fellow eye in amblyopia due to anisometropia.Methods: We recorded mfVEP in both eyes of 15 anisometropic amblyopic patients and 15 normal control subjects. The responses from the central 7.0° arc of the visual field were measured, and changes in latency and amplitude were compared between the amblyopic, fellow, and normal control eyes.Results: There was a significant difference in the latency and amplitude of mfVEP between the amblyopic and fellow eyes. The responses in the central region of the visual field (rings 1 and 2) had a longer latency and smaller amplitude in the amblyopic eye. In contrast, there was no difference in mfVEP latency or amplitude between the fellow eye and normal control eyes.Conclusion: These results suggest that mfVEP may be used as an alternative objective method for diagnosis and monitoring of anisometropic amblyopia.Keywords: amblyopia, anisometropia, multifocal visual evoked potentials