Self-medication appeared to be the initial effort of around 60% of the urban community in three cities on Java Island, in 1993. Drugs were used more frequently than the traditional medicines. Self-medication might potentially be an efficient self-help means for the community before getting the opportunity to reach the Primary health center. To achieve effectiveness of the self-medication effort, providing good information, how ever is strongly needed. The cross sectional study has been carried out among a rural community in two villages of Subdistrict Tanjung Bintang, in the Southern part of Lampung province. The sample population consist of housewives, who had ever taken drug or traditional medicines within the last month prior to the interview. Respondents (320 housewives) were choosen by multistage random sampling based on the number of households, RT and RW. Data were analyzed and presented as means and as the frequency distribution of the variables. The result obtained are : (1) A total of 74,5% prevalence was found taking drugs and traditional medicines for a period of one month, drugs how ever were used more frequently. (2) Drugs were taken as an effort in relieving their perceived headache, fever, or cough, according to their knowledge obtained from advertisement through television and radio programs. They got acces to the remedial products in small shops (warung), within a distance up to 500 meter from their home, without needing any transportation, and with a cost of Rp 194 (SD.± 289). (3) On the other hand, traditional medicines were taken as a remedy against diarrhoea, muscle-aches and health preventive/ fitness, according their knowledge received from their relatives and neighbours. They obtained the remedial product from the Vendors, within a distance up to 500 meter from thier dweeling place, without needing any transportation, and with a cost of Rp 407 (SD.± 500). (4) Effectiveness of the self-medication effort were perceived by around 78,5% and 72,2% of the user, for drug and traditional medicines respectively.