We consider relay channels in which the source-destination and relay-destination signals are assumed to be orthogonal and thus have to be recombined at the destination. Assuming memoryless signals at the destination and relay, we propose a low-complexity quantize-and-forward (QF) relaying scheme, which exploits the knowledge of the SNRs of the source-relay and relay-destination channels. Both in static and quasistatic channels, the quantization noise introduced by the relay is shown to be significant in certain scenarios. We therefore propose a maximum likelihood (ML) combiner at the destination, which is shown to compensate for these degradations and to provide significant performance gains. The proposed association, which comprises the QF protocol and ML detector, can be seen, in particular, as a solution for implementing a simple relaying protocol in a digital relay in contrast with the amplify-and-forward protocol which is an analog solution.