Introduction: Renal artery stenosis is the most prevalent disease of renal artery and has an important role in making hypertension and renal atrophy. Since in previous researches, despite high frequency of risk of cardiovascular disease in Iran, there did not exist any general research investigating risk factors of coronary artery disease and incidence of contemporary renal artery stenisis, this study intended to investigate these factors in hypertensive patients in Iran. Methods: This cross-sectional study was performed on 264 patients who were hypertension candidate for coronary artery angiography in Afshar hospital in Yazd. At the time of coronary angiography, patients had renal angiography at the same time. Among those patients, those who had coronary artery disease were selected and thus prevalence and severity of renal artery stenosis and its relationship with cardiovascular risks were investigated. The gathered data were analyzed by Spss-18 software. Results: Prevalence of renal artery stenosis (equal and over 50%) was 38.25 in all patients; in other words, in men and women it was 43.56% and 56.44% (P=0.04) respectively. Prevalence of co-morbidity of coronary artery disease and renal artery stenosis with 1 vessel disease was 34%, 2 vessel disease was 57.14% and 3 vessel disease was 54.17% with significant differences (P>0.01) Conclusion: According to high prevalence of renal artery stenosis in hypertensive patients and high prevalency with simultaneous hypertension and coronary artery disease, renal angiography after coronary angiography may assist for unknown renal artery stenosis and better treatment.