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ANTI-ULCER ACTIVITY OF ADHATODA VASICA LEAVES AGAINST GASTRIC ULCER IN RATS

DOI: 10.1234/jgpt.v3i2.346

Keywords: Adhatoda vasica , anti-ulcer , anti-secretory

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Abstract:

The effect of Methanolic,chloroform and diethel ether extracts of Adhatoda vasica was investigated in rats to evaluate the anti-ulcer activity by using three models, i.e. Aspirin, Alcohol and pyloric ligation models experimentally induced gastric ulcer. The parameters taken to assess anti-ulcer activity were volume of gastric secretion, PH, free acidity, total acidity and ulcer index. The results indicate that the alcoholic extract significantly (P < 0.001) decreases the volume of gastric acid secretion, PH, free acidity, total acidity and ulcer index with respect to control.

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